Results 11 to 20 of about 50,898 (285)

The impact of antibiotic selection and interval time among advanced non‐small cell lung cancer patients receiving prior antibacterial treatment and first‐line chemotherapy

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4849-4864, December 2022., 2022
In clinical settings, many NSCLC patients undergo antibiotic treatment prior to the initiation of chemotherapy. Previous studies have reported that antibiotic use can affect the efficacy of immunotherapeutic treatment regimens. Whether antibiotics similarly impact chemotherapy efficacy, however, remains to be established.
Xiaoman Tian   +5 more
wiley   +1 more source

Clinical Relevance of Drug–Drug Interactions With Antibiotics as Listed in a National Medication Formulary: Results From Two Large Population‐Based Case‐Control Studies in Patients Aged 65–100 Years Using Linked English Primary Care and Hospital Data

open access: yesClinical Pharmacology &Therapeutics, Volume 113, Issue 2, Page 423-434, February 2023., 2023
This study evaluated drug–drug interactions (DDIs) between antibiotic and nonantibiotic drugs listed with warnings of severe outcomes in the British National Formulary based on adverse drug reaction (ADR) detectable with routine International Classification of Diseases, Tenth Revision coding.
Tjeerd Pieter van Staa   +4 more
wiley   +1 more source

Use of antibiotics in women undergoing correction of an obstetric anal sphincter injury: Results from a national Israeli survey

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 160, Issue 1, Page 195-201, January 2023., 2023
Abstract Objective Obstetric anal sphincter injures (OASIS) have long‐term implications on women's health. Administration of antibiotic prophylaxis and treatment following OASIS repair is controversial. We conducted a national survey to provide data about practice routines regarding antibiotic prophylaxis and treatment following OASIS repair in Israeli
Moshe Barg   +5 more
wiley   +1 more source

Status and Safety Signals of Cephalosporins in Children: A Spontaneous Reporting Database Study

open access: yesFrontiers in Pharmacology, 2021
Introduction: Cephalosporins are widely used in clinical treatment of children, but it is difficult to carry out clinical trials and there is no strong evidence of their safety.
Yuanxuan Cai   +4 more
doaj   +1 more source

Probability of Target Attainment Analyses to Inform Ceftolozane/Tazobactam Dosing Regimens for Patients With Hospital‐Acquired or Ventilator‐Associated Bacterial Pneumonia and End‐Stage Renal Disease Receiving Intermittent Hemodialysis

open access: yesThe Journal of Clinical Pharmacology, Volume 63, Issue 2, Page 166-171, February 2023., 2023
Abstract ASPECT‐NP, a phase 3 trial of ceftolozane/tazobactam in hospital‐acquired/ventilator‐associated bacterial pneumonia (HABP/VABP), excluded patients with end‐stage renal disease (ESRD). A modeling/simulation approach was undertaken to inform optimal dosing in this population, using previously developed ceftolozane and tazobactam population ...
Hwa‐Ping Feng   +7 more
wiley   +1 more source

In vitro analysis of mediators of contact urticaria caused by cefotiam hydrochloride

open access: yesAllergology International, 1996
Contact urticaria syndrome is a rare but potentially serious problem for hospital staff that handle antibiotics and other agents. While the cause is immunologic, little is known about the mediators involved.
Hiroko Miyahara   +3 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Pyogenic liver abscess in non‐liver cancer patients and liver cancer patients treated with TACE: Etiological characteristics, treatment, and outcome analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 39, Issue 1, Page 87-94, January 2023., 2023
Abstract Clinical, laboratory, and microbiological features, clinical outcomes, and pyogenic liver abscess (PLA) prognosis evaluation in non‐liver cancer (Non‐LC) and liver cancer patients treated with transarterial chemoembolization (TACE, LC‐TACE). Clinical data of 48 consecutive PLA patients from January 2016 to December 2020 were retrospectively ...
Yi‐Ming Liu   +3 more
wiley   +1 more source

Effect of Antimicrobial Exposure in Pregnancy on Adverse Pregnancy Outcomes and Admission Rate to the Neonatal Intensive Care Unit: A Multi-Center Cohort Study

open access: yesInfection and Drug Resistance, 2023
Yueyan Li,1 Chen Zhang,2 Xuan Huang,1 Jing Tang1 1Department of Pharmacy, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of China; 2Institute of Reproduction and Development, Obstetrics and Gynecology Hospital of ...
Li Y, Zhang C, Huang X, Tang J
doaj  

Brand innovator versus multisource cefpodoxime in respiratory tract infections: A comparative study

open access: yesSouth African Family Practice, 2019
Purpose: In everyday practice clinicians are overwhelmed by claims from the pharmaceutical industry and, due to marketing efforts, they often view generic multisource products with scepticism despite proof and registration by regulatory authorities of ...
J. R. Snyman, C. E. Medlen
doaj   +1 more source

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