Results 21 to 30 of about 137,963 (330)

Metal complexes of penicillin and cephalosporin antibiotics [PDF]

, 1975
Includes bibliographical references.The interaction between metal-ions and the penicillin and cephalosporin antibiotics have been studied in an attempt to determine both the site and mechanism of this interaction.
Jackson, Graham Ellis
core   +1 more source

Signal Detection of Adverse Drug Reactions of Cephalosporins Using Data from a National Pharmacovigilance Database

Pharmaceuticals, 2021
This case-non-case study aims to detect signals not currently listed on cephalosporin drug labels. From 2009 to 2018, adverse event (AE) reports concerning antibacterial drugs (anatomical therapeutic chemical (ATC) code J01) in the Korea Adverse Events ...
Jung-Yoon Choi, Jae-Hee Choi, Myeong-Gyu Kim, Sandy-Jeong Rhie   +3 more
doaj   +1 more source

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

Angewandte Chemie, EarlyView.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika, Matthew Murray, Guillermo Palop, Lee‐Ann J. Keane, Patrick McArdle, Nicholas D. J. Yates, Christopher D. Spicer, Alison Parkin, Martin A. Fascione, Eddie L. Myers   +9 more
wiley   +2 more sources

Optimierung und Evaluierung von Enzymimmuntests zum Nachweis von Cephalosporin-Antibiotika in Milch [PDF]

, 2012
Die vorliegende Arbeit befasst sich mit der Entwicklung von monoklonalen Antikörpern (mAk) zum Nachweis verschiedener relevanter Cephalosporin-Rückstände.
Bremus, Anna Caroline
core   +1 more source

Structural and Functional Siderophore Remodeling by Enzymatic Delipidation

Angewandte Chemie, EarlyView.
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog, Keishi Ishida, Evelyn M. Molloy, Ron Hermenau, Kirstin Scherlach, Christian Hertweck   +5 more
wiley   +2 more sources

Alergia a beta-lactâmicos na clínica pediátrica: uma abordagem prática Allergy to beta-lactams in pediatrics: a practical approach

Jornal de Pediatria, 2006
OBJETIVO: Apresentar uma abordagem prática ao diagnóstico e conduta na alergia a antibióticos beta-lactâmicos. FONTES DOS DADOS: Periódicos da área de alergia indexados nas bases MEDLINE e LILACS, além de estudos e textos clássicos que tratam do tema ...
Nelson A. Rosário, Anete Sevciovic Grumach   +1 more
doaj   +1 more source

Prevalence of Extended-Spectrum β-Lactamase-Resistant Genes in Escherichia coli Isolates from Central China during 2016–2019

Animals, 2022
The emergence and dissemination of Escherichia coli (E. coli) strains that produce extended-spectrum beta-lactamases (ESBLs) represents a major public health threat.
Zui Wang, Qin Lu, Xiaohui Mao, Li Li, Junfeng Dou, Qigai He, Huabin Shao, Qingping Luo   +7 more
doaj   +1 more source

Rational Design of a Synthetic Galliphore for the Diagnostic Nuclear Imaging and Treatment of Bacterial Infections

Angewandte Chemie, EarlyView.
KO‐NH2 is a synthetic metallophore that preferentially binds Ga3+ over Fe3+ and is recognized by bacterial transporters. Photocrosslinking identifies CirA and Fiu as key uptake proteins in E. coli. KO‐NH2 enables targeted imaging and treatment of E. coli soft tissue infections.
Phuong Nguyen Tran, Axia Marlin, Edith K. Amason, Marie Huynh, Hannah Carlisle, Eszter Boros   +5 more
wiley   +2 more sources

Cefiderocol - a promising new antibiotic for the antibiotic-resistant pathogens of the highest epidemiological priority

Journal of Education, Health and Sport, 2019
Increase in the incidence of multidrug-resistant Gram-negative bacterial strains pose a significant threat to healthcare system worldwide. New antibiotics are necessary to combat particularly resitant pathogens.
Karol Lorenc Lorenc, Magdalena Kozioł, Alicja Sobek, Mateusz Pawlicki, Anna Łopuszyńska, Zofia Misztal, Marcin Lewicki, Agata Smoleń   +7 more
doaj   +3 more sources

Estudi experimental del tractament de la meningitis pneumocòcica produïda per soques resistents a cefalosporines de tercera generació. Virulència, eficàcia i resposta inflamatòria [PDF]

, 2006
[cat] La meningitis pneumocòcica és una malaltia associada a una elevada mortalitat (20-40) i a l'aparició de seqüeles neurològiques en un 30% dels pacients, nens i adults, que sobreviuen.
Ribes Miravet, Sandra
core   +4 more sources