Results 11 to 20 of about 137,963 (330)
The epidemiology of cephalosporin allergy labels in pediatric primary care [PDF]
Background: Recent studies have sought to understand the epidemiology and impact of beta-lactam allergy labels on children; however, most of these studies have focused on penicillin allergy labels.
Torsten Joerger +7 more
core +1 more source
Cephalosporins are beta-lactam antibiotics that are widely used in China. Five generations of cephalosporins have been introduced in clinical practice to date; moreover, some new candidates are also undergoing clinical evaluations. To improve the success
Ying Liu +3 more
doaj +1 more source
The arrival of new cephalosporins faces the clinician with an evergrowing confusion as to the drug of choice. The older agents (cephalexin, cephradine, cefadroxil and cefaclor) and the newer formulations cefatrizine and cefuroxime axetil are intensively used for treatment of mild and moderate infections.
J, Verhaegen, L, Verbist
openaire +4 more sources
Enterococcus faecalis and Enterococcus faecium are commensals of the gastrointestinal tract of most terrestrial organisms, including humans, and are major causes of health care-associated infections.
D. Djorić, Jaime L. Little, C. Kristich
semanticscholar +1 more source
Synthesis of Nuclearly-Modified Cephalosporin Antibiotics [PDF]
Approaches are described towards synthesis of 1-hydroxy-1-carba-cephalosporin (1), a chemically interesting nuclearly modified cephalosporin analogue which may possess potent antibiotic activity.
Gallacher, Gerard
core +6 more sources
Antimicrobial resistance (AR) is a public health issue since it limits the choices to treat infections by Escherichia coli in humans and animals. In Brazil, the ovine meat market has grown in recent years, but studies about AR in sheep are still scarce ...
Katia Suemi Gozi +10 more
doaj +1 more source
Cefiderocol: Discovery, Chemistry, and In Vivo Profiles of a Novel Siderophore Cephalosporin
The emergence of antimicrobial resistance is a significant public health issue worldwide, particularly for healthcare-associated infections caused by carbapenem-resistant gram-negative pathogens. Cefiderocol is a novel siderophore cephalosporin targeting
Takafumi Sato, K. Yamawaki
semanticscholar +1 more source
Cefiderocol (CFDC; S-649266), a novel parenteral siderophore cephalosporin conjugated with a catechol moiety, has a characteristic antibacterial spectrum with a potent activity against a broad range of aerobic Gram-negative bacterial species, including ...
Akinobu Ito +12 more
semanticscholar +1 more source
Cephalosporin Allergy: Current Understanding and Future Challenges
Cephalosporins are commonly used antibiotics both in hospitalized patients as well as outpatients. Hypersensitivity reactions to cephalosporins are becoming increasingly common with a wide range of immunopathologic mechanisms.
D. Khan +8 more
semanticscholar +1 more source
Pharmacokinetic and Pharmacodynamic Profiles of Cefiderocol, a Novel Siderophore Cephalosporin
Cefiderocol, a novel parenteral siderophore cephalosporin, exhibits potent in vitro activity and in vivo efficacy against most gram-negative bacteria, including carbapenem-resistant strains of Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter ...
T. Katsube, R. Echols, T. Wajima
semanticscholar +1 more source

