Results 11 to 20 of about 137,963 (330)

The epidemiology of cephalosporin allergy labels in pediatric primary care [PDF]

open access: yes, 2023
Background: Recent studies have sought to understand the epidemiology and impact of beta-lactam allergy labels on children; however, most of these studies have focused on penicillin allergy labels.
Torsten Joerger   +7 more
core   +1 more source

Construction of a Quantitative Structure Activity Relationship (QSAR) Model to Predict the Absorption of Cephalosporins in Zebrafish for Toxicity Study

open access: yesFrontiers in Pharmacology, 2019
Cephalosporins are beta-lactam antibiotics that are widely used in China. Five generations of cephalosporins have been introduced in clinical practice to date; moreover, some new candidates are also undergoing clinical evaluations. To improve the success
Ying Liu   +3 more
doaj   +1 more source

Oral Cephalosporins [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 1992
The arrival of new cephalosporins faces the clinician with an evergrowing confusion as to the drug of choice. The older agents (cephalexin, cephradine, cefadroxil and cefaclor) and the newer formulations cefatrizine and cefuroxime axetil are intensively used for treatment of mild and moderate infections.
J, Verhaegen, L, Verbist
openaire   +4 more sources

Multiple Low-Reactivity Class B Penicillin-Binding Proteins Are Required for Cephalosporin Resistance in Enterococci

open access: yesAntimicrobial Agents and Chemotherapy, 2020
Enterococcus faecalis and Enterococcus faecium are commensals of the gastrointestinal tract of most terrestrial organisms, including humans, and are major causes of health care-associated infections.
D. Djorić, Jaime L. Little, C. Kristich
semanticscholar   +1 more source

Synthesis of Nuclearly-Modified Cephalosporin Antibiotics [PDF]

open access: yes, 1980
Approaches are described towards synthesis of 1-hydroxy-1-carba-cephalosporin (1), a chemically interesting nuclearly modified cephalosporin analogue which may possess potent antibiotic activity.
Gallacher, Gerard
core   +6 more sources

Dissemination of Multidrug-Resistant Commensal Escherichia coli in Feedlot Lambs in Southeastern Brazil

open access: yesFrontiers in Microbiology, 2019
Antimicrobial resistance (AR) is a public health issue since it limits the choices to treat infections by Escherichia coli in humans and animals. In Brazil, the ovine meat market has grown in recent years, but studies about AR in sheep are still scarce ...
Katia Suemi Gozi   +10 more
doaj   +1 more source

Cefiderocol: Discovery, Chemistry, and In Vivo Profiles of a Novel Siderophore Cephalosporin

open access: yesClinical Infectious Diseases, 2019
The emergence of antimicrobial resistance is a significant public health issue worldwide, particularly for healthcare-associated infections caused by carbapenem-resistant gram-negative pathogens. Cefiderocol is a novel siderophore cephalosporin targeting
Takafumi Sato, K. Yamawaki
semanticscholar   +1 more source

In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria

open access: yesAntimicrobial Agents and Chemotherapy, 2017
Cefiderocol (CFDC; S-649266), a novel parenteral siderophore cephalosporin conjugated with a catechol moiety, has a characteristic antibacterial spectrum with a potent activity against a broad range of aerobic Gram-negative bacterial species, including ...
Akinobu Ito   +12 more
semanticscholar   +1 more source

Cephalosporin Allergy: Current Understanding and Future Challenges

open access: yesJournal of Allergy and Clinical Immunology: In Practice, 2019
Cephalosporins are commonly used antibiotics both in hospitalized patients as well as outpatients. Hypersensitivity reactions to cephalosporins are becoming increasingly common with a wide range of immunopathologic mechanisms.
D. Khan   +8 more
semanticscholar   +1 more source

Pharmacokinetic and Pharmacodynamic Profiles of Cefiderocol, a Novel Siderophore Cephalosporin

open access: yesClinical Infectious Diseases, 2019
Cefiderocol, a novel parenteral siderophore cephalosporin, exhibits potent in vitro activity and in vivo efficacy against most gram-negative bacteria, including carbapenem-resistant strains of Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter ...
T. Katsube, R. Echols, T. Wajima
semanticscholar   +1 more source

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