Results 31 to 40 of about 50,898 (285)

Predicting Beta-Lactam Target Non-Attainment in ICU Patients at Treatment Initiation: Development and External Validation of Three Novel (Machine Learning) Models

open access: yesAntibiotics, 2023
In the intensive care unit (ICU), infection-related mortality is high. Although adequate antibiotic treatment is essential in infections, beta-lactam target non-attainment occurs in up to 45% of ICU patients, which is associated with a lower likelihood ...
André Wieringa   +11 more
doaj   +1 more source

Oral flora of domestic cats in Hong Kong: Identification of antibiotic‐resistant strains

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 25-36, January 2023., 2023
Abstract Background As the clinical outcome of bite‐associated infection is related to the oral commensals, evaluating their composition and antibiotic susceptibility pattern can provide more information for the antibiotic treatment of wound infections and increase the awareness of the multidrug‐resistant bacteria in cat oral flora. Aims This study was
Ka Tik Cheung, Hau Yan Chan
wiley   +1 more source

Oral Cephalosporins [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 1992
The arrival of new cephalosporins faces the clinician with an evergrowing confusion as to the drug of choice. The older agents (cephalexin, cephradine, cefadroxil and cefaclor) and the newer formulations cefatrizine and cefuroxime axetil are intensively used for treatment of mild and moderate infections.
J, Verhaegen, L, Verbist
openaire   +4 more sources

Novel Cephalosporins in Septic Subjects and Severe Infections: Present Findings and Future Perspective

open access: yesFrontiers in Medicine, 2021
In past decade, cephalosporins have developed significantly, and data regarding novel cephalosporins (i.e., ceftobiprole, ceftaroline, ceftolozane/tazobactam, ceftazidime/avibactam, and cefiderocol) within septic and bacteremic subjects are rising. These
Silvia Corcione   +3 more
doaj   +1 more source

Infections caused by Clostridium difficile in cancer patients

open access: yesСибирский онкологический журнал, 2019
The purpose of the study was to determine the role of antibiotics as a risk factor of Clostridium difficile-associated diarrhea in hospitalized cancer patients.Material and Methods. The study included 844 hospitalized cancer patients with diarrhea.
I. A. Klyuchnikova   +5 more
doaj   +1 more source

Hydrolysis of Cephalexin and Meropenem by New Delhi Metallo $β$-Lactamase: Substrate Protonation Mechanism is Drug Dependent [PDF]

open access: yes, 2017
Emergence of antibiotic resistance due to New Delhi Metallo $\beta$-lactamase (NDM-1) bacterial enzymes is of great concern due to their ability to hydrolyze wide range of antibiotics. Efforts are ongoing to obtain the atomistic details of the hydrolysis mechanism in order to develop novel drugs and inhibitors against NDM-1.
arxiv   +1 more source

Comparison of Epidemiological Characteristics Between ESBL and Non-ESBL Isolates of Clinically Isolated Escherichia coli from 2014 to 2022: A Single-Center Study

open access: yesInfection and Drug Resistance, 2023
Wei Zhang,1,2,* Qing Wang,3,* Liru Zhang,4,* Jiangxiong Wu,5 Jinlu Liu,2 Cheng Lu,2 Xinsheng Wang,1 Zhihua Zhang6 1Central Laboratory, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, People’s Republic of China ...
Zhang W   +7 more
doaj  

Construction of a Quantitative Structure Activity Relationship (QSAR) Model to Predict the Absorption of Cephalosporins in Zebrafish for Toxicity Study

open access: yesFrontiers in Pharmacology, 2019
Cephalosporins are beta-lactam antibiotics that are widely used in China. Five generations of cephalosporins have been introduced in clinical practice to date; moreover, some new candidates are also undergoing clinical evaluations. To improve the success
Ying Liu   +3 more
doaj   +1 more source

Alergia a beta-lactâmicos na clínica pediátrica: uma abordagem prática Allergy to beta-lactams in pediatrics: a practical approach

open access: yesJornal de Pediatria, 2006
OBJETIVO: Apresentar uma abordagem prática ao diagnóstico e conduta na alergia a antibióticos beta-lactâmicos. FONTES DOS DADOS: Periódicos da área de alergia indexados nas bases MEDLINE e LILACS, além de estudos e textos clássicos que tratam do tema ...
Nelson A. Rosário   +1 more
doaj   +1 more source

Factors influencing dairy cattle farmer use of antimicrobials on farms in New South Wales, Australia

open access: yesAustralian Veterinary Journal, Volume 100, Issue 12, Page 587-595, December 2022., 2022
Antimicrobial use (AMU) in the food chain is a potential driver of antimicrobial resistance. Despite Australia's strong regulation of AMU limited to veterinary prescriptions, a proportion of empirical antimicrobial treatments are administered by dairy farmers to manage common cattle health problems. This cross‐sectional survey identified key influences
E Doyle, J Heller, JM Norris
wiley   +1 more source

Home - About - Disclaimer - Privacy