Results 211 to 220 of about 34,100 (243)

Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. [PDF]

J Clin Invest, 2019
Suzuki M, Cao K, Kato S, Komizu Y, Mizutani N, Tanaka K, Arima C, Tai MC, Yanagisawa K, Togawa N, Shiraishi T, Usami N, Taniguchi T, Fukui T, Yokoi K, Wakahara K, Hasegawa Y, Mizutani Y, Igarashi Y, Inokuchi JI, Iwaki S, Fujii S, Satou A, Matsumoto Y, Ueoka R, Tamiya-Koizumi K, Murate T, Nakamura M, Kyogashima M, Takahashi T.   +29 more
europepmc   +2 more sources

Ceramide synthase 4 : a novel metabolic regulator of oncogene-induced senescence

, 2018
Flora Lucy Dix
openalex   +1 more source

Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage

, 2008
Duška Šeparović, Louie Semaan, Adi L. Tarca, Ma'in Y. Maitah, Kentaro Hanada, Jacek Bielawski, Maristella Villani, Chiara Luberto   +7 more
openalex   +2 more sources

A turn in the road: How studies on the pharmacology of glucosylceramide synthase inhibitors led to the identification of a lysosomal phospholipase A2 with ceramide transacylase activity

, 2003
James A. Shayman, Akira Abe, Miki Hiraoka   +2 more
openalex   +2 more sources

Lipidomics Suggests a New Role for Ceramide Synthase in Phagocytosis. [PDF]

ACS Chem Biol, 2018
Pathak D, Mehendale N, Singh S, Mallik R, Kamat SS.   +4 more
europepmc   +1 more source

Grasping the duality of fumonisins versus ceramide synthases: a computational approach to study their role as inhibitors and substrates from a mechanistic standpoint

Florinda Perugino, Lorenzo Pedroni, Gianni Galaverna, Chiara Dall’Asta, Luca Dellafiora   +4 more
openalex   +1 more source

Ping, pong, and freeze: Structural insights into the inhibition of ceramide synthase by Fumonisin B1

Kexin Hu, Yu Cao
openalex   +2 more sources

S4 Fig - Individual lipid alterations at the origin of neuronal Ceramide Synthase defects

Anna B. Ziegler (7691084), Cedrik Wesselmann (22311822), Konstantin Beckschäfer (22311825), Anna-Lena Wulf (22311828), Neena Dhiman (5074757), Peter Soba (10654038), Christoph Thiele (20014), Reinhard Bauer (437078), Gaia Tavosanis (502448)   +8 more
openalex   +1 more source

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Inhibitors of specific ceramide synthases

Biochimie, 2012
Ceramide synthases (CerSs) are key enzymes in the biosynthesis of ceramides and display a group of at least six different isoenzymes (CerS1-6). Ceramides itself are bioactive molecules. Ceramides with different N-acyl side chains (C(14:0)-Cer - C(26:0)-Cer) possess distinct roles in cell signaling.
Susanne, Schiffmann, Daniela, Hartmann, Sina, Fuchs, Kerstin, Birod, Nerea, Ferreiròs, Yannick, Schreiber, Aleksandra, Zivkovic, Gerd, Geisslinger, Sabine, Grösch, Holger, Stark   +9 more
openaire   +2 more sources

Ceramide synthases in biomedical research

Chemistry and Physics of Lipids, 2016
Sphingolipid metabolism consists of multiple metabolic pathways that converge upon ceramide, one of the key molecules among sphingolipids (SLs). In mammals, ceramide synthesis occurs via N-acylation of sphingoid backbones, dihydrosphingosine (dhSo) or sphingosine (So). The reaction is catalyzed by ceramide synthases (CerS), a family of enzymes with six
Francesca, Cingolani, Anthony H, Futerman, Josefina, Casas   +2 more
openaire   +2 more sources