Results 141 to 150 of about 23,863 (196)

Dysregulated metabolism of ceramides and glycosphingolipids in Parkinson's disease. [PDF]

J Lipid Res
Peng YF, Chen SJ, Li JL, Lin CH, Kuo CH.
europepmc   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

Ceramide-based machine learning models for the diagnosis of unstable angina: a prospective multicenter study. [PDF]

Eur J Med Res
Xie Z, Xin S, Zhao X, Zeng Y, Chang C, Zhang L, Ma F, Miao M, Wang G, Zhang R, Li Q, An J, Zheng M.   +12 more
europepmc   +1 more source

Adipocytes in Aortic Stenosis: Association With Clinical and Morphological Indices

Clinical Anatomy, Volume 39, Issue 3, Page 325-331, April 2026.
ABSTRACT Recently, great attention has been given to understanding the new pathogenetic mechanisms underlying aortic stenosis (AS). The study aims to understand the role of mature adipocytes in AS and their association with histologic, clinical, and echocardiographic data, an area previously overlooked in AS research.
Elena Zoico, Tanaz Saatchi, Silvia Urbani, Vanni Rizzatti, Gloria Mazzali, Francesco Fantin, Silvia Faccioli, Alessandro Gavras, Mauro Zamboni, Anna Giani   +9 more
wiley   +1 more source

Exploring Ceramide C16:0 as a Novel Biomarker and Therapeutic Target for Atherosclerosis. [PDF]

J Am Heart Assoc
Chen T, Xie L, Zhao Y, Shang Y, Pan Y, Wang W, Mao W.   +6 more
europepmc   +1 more source

Linking physical stimulation to molecular responses: The role and value of exosomes in mediating the systemic effects of Chinese Tuina

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
(1) Tuina's mechanical forces activate cellular mechanosensors; (2) Induce multi‐tissue exosome release to mediate intercellular communication; (3) Exosomes systemically regulate muscle, nerve, immune and vascular functions; (4) Target gene knockout confirms exosomes’ specific mediating role.
Lifen Zhan, Ji Zhang, Yiping Chen, Suyu Chen, Xiantao Tai   +4 more
wiley   +1 more source

Targeting Sphingolipids in Breast Cancer: From Tumor Biology to Therapeutic Strategies. [PDF]

Oncol Res
Kim MH, Huh B, Park JW, Park WJ.
europepmc   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, Volume 183, Issue 7, Page 1404-1426, April 2026.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

Two G protein-coupled receptors bind ceramides in atherosclerosis progression: targets for a new therapeutic strategy. [PDF]

Signal Transduct Target Ther
Han Y, Illes P, Tang Y.
europepmc   +1 more source

Skin Barrier Biomarkers in Patch‐Induced and Clinical Allergic and Irritant Contact Dermatitis

Contact Dermatitis, Volume 94, Issue 4, Page 317-326, April 2026.
Both patch‐induced and clinical ICD and ACD showed consistent alterations in skin barrier‐associated biomarkers, indicative of skin barrier impairment. Among the tested allergens, chromium elicited more pronounced biomarker responses compared to nickel and methylisothiazolinone.
Sanja Kezic, Florentine de Boer, Nariman K. A. Metwally, Karen Ghauharali‐van der Vlugt, Femke S. Beers‐Stet, Wouter Ouwerkerk, Ivone Jakasa, Thomas Rustemeyer, Henk F. van der Molen   +8 more
wiley   +1 more source