Results 191 to 200 of about 33,232 (287)

Proinflammatory Stress Activates Neutral Sphingomyelinase 2-Based Generation of a Ceramide-Enriched β-Cell EV Subpopulation. [PDF]

Diabetes
Xu J, Amalaraj I, De Oliveira A, Harris-Kawano A, Enriquez JR, Mirmira RG, Eder JG, Burnet MC, Díaz Ludovico I, Flores JE, Nakayasu ES, Sims EK.   +11 more
europepmc   +1 more source

Prevention of Atopic Dermatitis in High‐Risk Infants: A Review of the Role of Lipid‐Based Barrier Repair Therapy

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan, Marty O. Visscher   +1 more
wiley   +1 more source

Ceramides in cardiovascular disease: emerging role as independent risk predictors and novel therapeutic targets. [PDF]

Cardiovasc Res
Klingenberg R, Leiherer A, Dobrev D, Kaski JC, Levkau B, März W, Sossalla S, von Eckardstein A, Drexel H.   +8 more
europepmc   +1 more source

Fas-induced apoptosis of T cells occurs independently of ceramide generation

, 1997
Julian D. Watts, M. F. Gu, Anthony Polverino, Scott D. Patterson, Ruedi Aebersold   +4 more
openalex   +2 more sources

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

Metabolic crossroads in insulin resistance: exploring lipid dysregulation and inflammation. [PDF]

Front Immunol
Saadati S, Godini R, Reddy A, Teede H, Mousa A.   +4 more
europepmc   +1 more source

Ceramide‐induced translocation of protein kinase C ζ in primary cultures of astrocytes [PDF]

, 1997
Ismael Galve‐Roperh, Amador Haro, Inés Dı́az-Laviada   +2 more
openalex   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

Ceramide Generated by Sphingomyelin Hydrolysis and the Salvage Pathway Is Involved in Hypoxia/Reoxygenation-induced Bax Redistribution to Mitochondria in NT-2 Cells [PDF]

, 2008
Junfei Jin, Qi Hou, Thomas D. Mullen, Youssef H. Zeidan, Jacek Bielawski, Jacqueline M. Kraveka, Alicja Bielawska, Lina M. Obeid, Yusuf A. Hannun, Yi Te Hsu   +9 more
openalex   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source