Results 121 to 130 of about 5,502 (160)

Discovery of SMD-6346: A Potent, Selective, and Orally Active SMARCA2 Degrader for Targeting SMARCA4-Deficient Human Cancers. [PDF]

J Med Chem
Leng L, Huang L, Tu W, Jiang W, Rej RK, Allu SR, Wang Y, Wang M, Tošović J, Wang M, Wen B, Sun D, Wang S.   +12 more
europepmc   +1 more source

Direct phospho-proteoform delivery reveals a degradation-prone monomeric state of 14-3-3. [PDF]

Chem Sci
Mathis MH, Stanisheuski S, Mehl RA, Cooley RB.   +3 more
europepmc   +1 more source

Forimtamig: a potent GPRC5D-targeted bispecific antibody in multiple myeloma. [PDF]

Ann Med Surg (Lond)
Ali H, Hilal H, Gul M, Asad M, Jaber Amin MH.   +4 more
europepmc   +1 more source

Chelator Free Radiolabeling and Preclinical Evaluation of η⁶-Arene Sandwich Complexes of Lenalidomide With Rhenium and Technetium-99m. [PDF]

Chembiochem
Nadeem Q, Battistin F, Valdés DH, Genady AR, Mendez LRS, Sadeghi S, Blacque O, Alberto R.   +7 more
europepmc   +1 more source

Selective degradation of platelet BTK by PROTAC NX-5948 provides antithrombotic benefits without affecting hemostasis. [PDF]

Blood Adv
May CJ, Trory JS, Webb CE, Walker HS, Li Y, Furniss JA, Eble JA, Poole AW, Vautrinot J, Tromans J, Hers I.   +10 more
europepmc   +1 more source

Monoterpenoid fluorophthalimide IMiDs that lack human cereblon binding: synthesis and anti-proliferative, anti-angiogenic and anti-inflammatory activities. [PDF]

Biochem Biophys Res Commun
Luo W, Garchitorena KM, Tweedie D, Chau CH, Patel CN, Siegler MA, Vargesson N, Hwang I, Kim S, Kim DS, Figg WD, Greig NH.   +11 more
europepmc   +1 more source

The Role of CELMoD Agents in Multiple Myeloma. [PDF]

Onco Targets Ther
van de Donk NWCJ, van de Donk NWCJ, Bahlis NJ, Pawlyn C, Gay F, Mateos MV, Weisel K, Lonial S, Richardson PG.   +8 more
europepmc   +1 more source

Catalyst-Free Photoinduced Deaminative Functionalization of Amino Acids and Glutarimide Precursors. [PDF]

J Am Chem Soc
Chong TG, Dorsheimer JR, Zhu Z, Sherwood TC, Joe CL, Welin ER, Rovis T.   +6 more
europepmc   +1 more source

Bridging E3 Ligase Binding and Targeted Degradation Through Fluorescence Polarization. [PDF]

Int J Mol Sci
González-Pico L, Camino T, Ortigueira S, Prieto-Díaz R, Sotelo E, Majellaro M.   +5 more
europepmc   +1 more source

Novel Cereblon-Binding Immunomodulators Have Increased Potency Against Gammaherpesvirus- Associated Lymphomas In Vitro. [PDF]

J Med Virol
Shrestha P, Treco EN, Davis DA, Yarchoan R.   +3 more
europepmc   +1 more source