Familial Multiple Cavernous Malformation Syndrome: MR Features in This Uncommon but Silent Threat [PDF]
Journal of the Belgian Society of Radiology, 2016 Cerebral cavernous malformations (CCM) are vascular malformations in the brain and spinal cord. The familial form of cerebral cavernous malformation (FCCM) is uncommon.
Marc Mespreuve +2 more
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Cranial ultrasonography in diagnosis of infantile cerebral cavernous malformation [PDF]
Clinical Case Reports, 2023 The case of an infantile cerebral cavernous malformation detected by transfontanelle cranial ultrasonography. Infantile cerebral cavernous malformations tend to cause more major bleeding compared to those in older groups, so early detection and treatment
Shuya Kaneko, Iku Ikeno, Hideo Wada
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Cerebral Cavernous Malformation: From Genetics to Pharmacotherapy [PDF]
Brain and BehaviorIntroduction Cerebral cavernous malformation (CCM) is a type of cerebrovascular abnormality in the central nervous system linked to both germline and somatic genetic mutations.
Zhuangzhuang Zhang +3 more
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Cerebral Cavernous Malformation: Immune and Inflammatory Perspectives [PDF]
Frontiers in Immunology, 2022 Cerebral cavernous malformation (CCM) is a type of vascular anomaly that arises due to the dyshomeostasis of brain capillary networks. In the past two decades, many advances have been made in this research field.
Tianqi Tu +6 more
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Inflammatory Mechanisms in a Neurovascular Disease: Cerebral Cavernous Malformation [PDF]
Brain Sciences, 2023 Cerebral cavernous malformation (CCM) is a common cerebrovascular malformation causing intracranial hemorrhage, seizures, and focal neurologic deficits.
Ying Li +9 more
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A Spinal Cavernous Malformation in Multiple Cerebral Cavernous Venous Malformations Syndrome
Journal of the Belgian Society of Radiology, 2023 Teaching Point: In patients with familial multiple cavernous malformation syndrome with acute focal neurological deficit, a symptomatic spinal cavernous malformation must be included in the differential diagnosis.
Guillaume Vangrinsven +2 more
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Functional outcome after pediatric cerebral cavernous malformation surgery [PDF]
Scientific Reports, 2023 The purpose of this study was to investigate the functional outcome following surgical resection of cerebral cavernous malformations (CCM) in pediatric patients.
Laurèl Rauschenbach +11 more
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The Role of Immune Infiltration and Oxidative Stress in the Progression of Cerebral Cavernous Malformation [PDF]
Brain and BehaviorPurpose of Review To review how the immune microenvironment and oxidative stress modulate the initiation, maturation, and hemorrhagic conversion of cerebral cavernous malformations (CCM) and to appraise the therapeutic potential of immune‐directed ...
Xuesai Zhu +3 more
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Case Report: A novel heterozygous nonsense mutation in KRIT1 cause hereditary cerebral cavernous malformation [PDF]
Frontiers in Oncology, 2023 Cerebral cavernous malformation (CCM) is a vascular malformation of the central nervous system and mainly characterized by enlarged capillary cavities without intervening brain parenchyma. Genetic studies have identified three disease-causing genes (CCM1/
Zhenxing Liu +3 more
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Progress on clinical characteristics and pathogenesis of cerebral cavernous malformation in children
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Cerebral cavernous malformation is the second most common vascular malformation of the central nervous system. The main clinical manifestations in children include epileptic seizure, spontaneous cerebral hemorrhage, and focal neurological deficits.
HAN Guo⁃qing, PU Ke, LI Qing⁃guo
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