Results 181 to 190 of about 138,758 (293)

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

open access: yesNeuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher   +8 more
wiley   +1 more source

Post‐recanalization administration of rapamycin improves functional outcome and reduces infarct size in a rat model of ischemic stroke

open access: yesNeuroprotection, EarlyView.
Experimental design and main findings of the study. Transient middle cerebral artery occlusion was induced for 90 min in rats, followed by intravenous administration of rapamycin or vehicle at the time of recanalization. Functional outcome (Garcia scale and adhesive removal test), magnetic resonance imaging‐based infarct volume assessment, and cerebral
Anna M. Schneider   +4 more
wiley   +1 more source

Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease

open access: yesNeuroprotection, EarlyView.
In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong   +3 more
wiley   +1 more source

Infarto cerebral embólico y edema cerebral

open access: yesMedisur, 2016
Jorge Julián Sánchez Fernández   +1 more
doaj   +2 more sources

Efficacy of Docetaxel Plus Ramucirumab for Malignant Pleural Effusion and Cerebral Edema in Patients With Advanced Non-Small Cell Lung Cancer: A Single-Institution Retrospective Study. [PDF]

open access: yesThorac Cancer
Morita M   +14 more
europepmc   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij   +11 more
wiley   +1 more source

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