Results 11 to 20 of about 1,244,067 (429)

Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022
Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao   +8 more
wiley   +1 more source

Altered expression of the immunoregulatory ligand-receptor pair CD200-CD200R1 in the brain of Parkinson’s disease patients

open access: yesnpj Parkinson's Disease, 2022
Neuroinflammation, in which activated microglia are involved, appears to contribute to the development of Parkinson’s disease (PD). However, the role of microglial activation and the mechanisms governing this process remain uncertain.
Neus Rabaneda-Lombarte   +8 more
doaj   +1 more source

MicroRNAs in Cerebral Ischemia [PDF]

open access: yesStroke Research and Treatment, 2013
The risk of ischemic stroke increases substantially with age, making it the third leading cause of death and the leading cause of long-term disability in the world. Numerous studies demonstrated that genes, RNAs, and proteins are involved in the occurrence and development of stroke. Current studies found that microRNAs (miRNAs or miRs) are also closely
Yang Wang, Yongting Wang, Guo-Yuan Yang
openaire   +4 more sources

Effects and Mechanisms of Exosomes from Different Sources in Cerebral Ischemia

open access: yesCells, 2022
Cerebral ischemia refers to the symptom of insufficient blood supply to the brain. Cells of many different origins participate in the process of repairing damage after cerebral ischemia occurs, in which exosomes secreted by the cells play important roles.
Ruoxi Xie   +4 more
doaj   +1 more source

The Alterations in Mitochondrial Dynamics Following Cerebral Ischemia/Reperfusion Injury

open access: yesAntioxidants, 2021
Cerebral ischemia results in a poor oxygen supply and cerebral infarction. Reperfusion to the ischemic area is the best therapeutic approach. Although reperfusion after ischemia has beneficial effects, it also causes ischemia/reperfusion (I/R) injury ...
Jirapong Vongsfak   +5 more
doaj   +1 more source

Establishment and Evaluation of a Monkey Acute Cerebral Ischemia Model [PDF]

open access: yesClinics, 2020
OBJECTIVES: Cerebral ischemia seriously threatens human health and is characterized by high rates of incidence, disability and death. Developing an ideal animal model of cerebral ischemia that reflects the human clinical features is critical for ...
Li Yan   +11 more
doaj   +1 more source

Histological disorders of neurons of phylogenetically different parts of the cerebral cortex in partial, subtotal, stepwise subtotal, and total cerebral ischemia

open access: yesJournal of Medical Science, 2021
Aim. Measure of the histological changes in neurons in the parietal cortex and hippocampus of rats with partial, subtotal, stepwise subtotal, and total cerebral ischemia. Material and Methods. Studies were performed on 84 rats. Partial cerebral ischemia
Lizaveta I. Bon, Nataliya Y. Maksimovich
doaj   +1 more source

Insights into the neuropathology of cerebral ischemia and its mechanisms

open access: yesReviews in the Neurosciences, 2020
Cerebral ischemia is a result of insufficient blood flow to the brain. It leads to limited supply of oxygen and other nutrients to meet metabolic demands. These phenomena lead to brain damage.
M. Ahad   +11 more
semanticscholar   +1 more source

The transcriptome of cerebral ischemia [PDF]

open access: yesBrain Research Bulletin, 2012
The molecular causality and response to stroke is complex. Yet, much of the literature examining the molecular response to stroke has focused on targeted pathways that have been well-characterized. Consequently, our understanding of stroke pathophysiology has made little progress by way of clinical therapeutics since tissue plasminogen activator was ...
Charles L. Rosen   +3 more
openaire   +2 more sources

AG490 protects cerebral ischemia/reperfusion injury via inhibiting the JAK2/3 signaling pathway

open access: yesBrain and Behavior, 2021
Background Cerebral ischemia/reperfusion injury is a severe problem in patients with brain ischemia. Brain injury caused by the immune response is important in the pathogenesis of cerebral ischemia/reperfusion injury and immune pathways.
Lichao Fan, Lichun Zhou
doaj   +1 more source

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