Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium [PDF]
Cytochrome P450 epoxygenases (CYP) metabolize arachidonic acid to epoxyeicosatrienoic acids (EETs), which exhibit vasodilatory, anti-inflammatory and neuroprotective actions in experimental cerebral ischemia.
Alkayed, Nabil J.+14 more
core +2 more sources
Oligodendrogenesis after cerebral ischemia [PDF]
Neural stem cells in the subventricular zone (SVZ) of the lateral ventricle of adult rodent brain generate oligodendrocyte progenitor cells (OPCs) that disperse throughout the corpus callosum and striatum where some of OPCs differentiate into mature oligodendrocytes.
Ruilan Zhang+3 more
openaire +4 more sources
Relationship between Hypotension and Cerebral Ischemia during Hemodialysis.
The relationship between BP and downstream ischemia during hemodialysis has not been characterized. We studied the dynamic relationship between BP, real-time symptoms, and cerebral oxygenation during hemodialysis, using continuous BP and cerebral ...
C. MacEwen+4 more
semanticscholar +1 more source
Trusting Machine Learning Results from Medical Procedures in the Operating Room [PDF]
Machine learning can be used to analyse physiological data for several purposes. Detection of cerebral ischemia is an achievement that would have high impact on patient care. We attempted to study if collection of continous physiological data from non-invasive monitors, and analysis with machine learning could detect cerebral ischemia in tho different ...
arxiv
Tonic activation of extrasynaptic NMDA receptors decreases intrinsic excitability and promotes bistability in a model of neuronal activity [PDF]
NMDA receptors (NMDA-R) typically contribute to excitatory synaptic transmission in the central nervous system. While calcium influx through NMDA-R plays a critical role in synaptic plasticity, experimental evidence indicates that NMDAR-mediated calcium influx also modifies neuronal excitability through the activation of calcium-activated potassium ...
arxiv +1 more source
Anticoagulation in cerebral ischemia. [PDF]
Anticoagulation clearly benefits patients at risk of stroke from cerebral embolism. Conversely, patients with completed ischemic stroke are not benefited, and may show a higher mortality and morbidity because of hemorrhagic complications. Technical advances in the early, accurate diagnosis of cerebral hemorrhage, the constant infusion of heparin, and ...
Babette B. Weksler, Margaret Lewin
openaire +3 more sources
RatLesNetv2: A Fully Convolutional Network for Rodent Brain Lesion Segmentation [PDF]
We present a fully convolutional neural network (ConvNet), named RatLesNetv2, for segmenting lesions in rodent magnetic resonance (MR) brain images. RatLesNetv2 architecture resembles an autoencoder and it incorporates residual blocks that facilitate its optimization.
arxiv +1 more source
Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 [PDF]
FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have shown that intraventricularly or systemically administered FGF-2 reduces the size of cerebral ...
Bohlen und Halbach, Oliver von+6 more
core
Hemodilution for cerebral ischemia. [PDF]
Evaluation du role de l'hemodilution hypervolemique ou normovolemique dans le traitement de l'accident ...
Roberto C. Heros, Kazuyoshi Korosue
openaire +3 more sources
The purpose of this study was to discuss the effect of voluntary wheel running on striatal dopamine levels and anxiety-like behavior in rats with global cerebral ischemia.
Yongzhao Fan+3 more
doaj +1 more source