The role of microglia and myeloid immune cells in acute cerebral ischemia
Frontiers in Cellular Neuroscience, 2015 The immune response to acute cerebral ischemia is a major contributor to stroke pathobiology. The inflammatory response is characterized by the participation of brain resident cells and peripheral leukocytes.
Corinne Benakis +3 more
semanticscholar +1 more source
Assessing the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemia [PDF]
, 2017 Numerous analyses have explored the role of statins in reducing stroke incidence, reducing cerebral ischemia in hypercholesterolemic patients, and preventing ischemic stroke.
AlSulaiman, Wafa
core
Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock. [PDF]
, 2009 The 5-lipoxygenase (5-LO) pathway is responsible for the production of leukotrienes (LTs), inflammatory lipid mediators which play a role in innate immunity. More recently, a pivotal role of LTs in ischemia-reperfusion and shock injury has been suggested.
CUZZOCREA S +2 more
core +1 more source
Neural Regeneration ResearchThe cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart, liver, brain, and kidney, but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically reviewed.
Hang Yang +6 more
doaj +1 more source
Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils [PDF]
, 2001 The time course of oxidative damage in different brain regions was investigated in the gerbil model of transient cerebral ischemia. Animals were subjected to both common carotid arteries occlusion for 5 min.
Al-Dalain, Saied M. +4 more
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Selenium-Binding Protein 1 Indicates Myocardial Stress and Risk for Adverse Outcome in Cardiac Surgery [PDF]
, 2019 Selenium-binding protein 1 (SELENBP1) is an intracellular protein that has been detected in the circulation in response to myocardial infarction. Hypoxia and cardiac surgery affect selenoprotein expression and selenium (Se) status.
Kühn, Eike C. +8 more
core +1 more source
Journal of Cerebral Blood Flow and Metabolism, 2015 Toll-like receptor 4 (TLR4) contributes to cerebral ischemia/reperfusion (I/R) injury and is a potential target for the treatment of ischemic stroke.
F. Hua +6 more
semanticscholar +1 more source
A review of medicinal herbs with antioxidant properties in the treatment of cerebral ischemia and reperfusion [PDF]
, 2015 BACKGROUND AND OBJECTIVE: Stroke is the second most common cause of death and a major cause of disability in individuals aged over 65 years, worldwide.
Bigdeli, M.R. +2 more
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Animal models of ischaemic stroke and characterisation of the ischaemic penumbra [PDF]
, 2018 Over the past forty years, animal models of focal cerebral ischaemia have allowed us to identify the critical cerebral blood flow thresholds responsible for irreversible cell death, electrical failure, inhibition of protein synthesis, energy depletion ...
Arroja, Mariana M. +3 more
core +1 more source
MicroRNAs Regulate Mitochondrial Function in Cerebral Ischemia-Reperfusion Injury
International Journal of Molecular Sciences, 2015 Cerebral ischemia-reperfusion injury involves multiple independently fatal terminal pathways in the mitochondria. These pathways include the reactive oxygen species (ROS) generation caused by changes in mitochondrial membrane potential and calcium ...
Yue Hu +3 more
semanticscholar +1 more source