Results 81 to 90 of about 460,913 (180)

Cerebral ischemia studied with positron emission tomography and microdialysis [Elektronisk resurs]

, 2002
Stroke is the third leading cause of morbidity and mortality in the industrialized world. Subarachnoid hemorrhage (SAH), the least common form of stroke, is one of the most demanding diseases treated in neurointensive care units.
Frykholm, Peter,, Kirkpatrick, Peter,
core   +6 more sources

Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome-c-Oxidase in Traumatic Brain Injury Patients during Hypercapnoea A Broadband NIRS Study [PDF]

, 2011
Using broadband near-infrared spectroscopy (NIRS) and cerebral micro-dialysis (MD), we investigated cerebral cellular metabolism and mitochondrial redox states, following hypercapnoea in 6 patients with traumatic brain injury (TBI).
Tachtsidis, I, Ghosh, A, Tisdall, MM, Elwell, CE, Pritchard, C, Leung, TS, Smith, M   +6 more
core  

Use of long-term microdialysis subcutaneous glucose monitoring in the management of neonatal diabetes - A first case report [PDF]

, 2006
In neonatal diabetes mellitus (NDM), a rare genetic disorder, insulin therapy is required but the management is difficult. Frequent blood glucose determinations are necessary in most cases. Microdialysis subcutaneous glucose monitoring (MSGM) is feasible
Holzinger, Andreas, Bonfig, Walter, Eggermann, Thomas, Münch, Hans-Georg, Kusser, Beate, Müller, Herbert   +5 more
core   +1 more source

Spatial Memory Impairment Without Apoptosis Induced by the Combination of Beta-Amyloid Oligomers and Cerebral Ischemia Is Related to Decreased Acetylcholine Release in Rats

Journal of Pharmacological Sciences, 2008
The purpose of the present study was to examine the effect of beta-amyloid (Aβ ) oligomers, not the fibrils that make up Aβ plaques, on spatial memory and the cholinergic system in rats.
Takuya Watanabe, Katsunori Iwasaki, Shin Ishikane, Tetsuya Naitou, Yoshitaka Yoshimitsu, Norito Yamagata, Mehmeto Bülent Ozdemir, Kotaro Takasaki, Nobuaki Egashira, Kenichi Mishima, Michihiro Fujiwara   +10 more
doaj   +1 more source

Microdialysis in CNS PKPD Research: Unraveling Unbound Concentrations

, 2012
The pharmacokinetic (PK) processes of drug movements between blood and tissues and the drug concentration profiles within a tissue over time can be described with the help of microdialysis sampling.
Hammarlund-Udenaes, Margareta,, Margareta Hammarlund-Udenaes   +1 more
core   +1 more source

A 4 day-clinical microdialysis monitoring in a patient with traumatic brain injury (tbi) suggests a possible link between brain serotonin and cerebral energy metabolism

, 2015
International audienceWhile the continuous microdialysis monitoring of cerebral biomarkers of energy metabolism is frequently used in neurocritical care, very few data on monoamine neurotransmitters, such as serotonin (5-HT), have been reported using ...
Denoroy, L., Gallet, Marlène, Renaud, B., Algoud, M., Parrot, S., Dailler, F., Goncalves, D.   +6 more
core   +1 more source

Is continuous insulin treatment safe in aneurysmal subarachnoid hemorrhage?

Vascular Health and Risk Management, 2008
Florian Schlenk, Asita S SarrafzadehClinic of Neurosurgery, Charité Campus Virchow Medical Center, Berlin, GermanyObjectives: To investigate the long-term effect of continuous insulin infusion for glucose control on cerebral metabolism in ...
Florian Schlenk, Asita S Sarrafzadeh
doaj  

Microdialysis in CNS PKPD research: Unraveling unbound concentrations

, 2013
With the help of microdialysis sampling, we can describe pharmacokinetic processes of drug movement between blood and tissues, and can describe concentration profiles within a tissue over time.
Hammarlund-Udenaes, Margareta,
core   +1 more source

Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting

Frontiers in Neurology, 2014
Cerebral microdialysis (MD) was introduced as a neurochemical monitoring tool in the early 1990s and is currently well established for the sampling of low molecular weight biomarkers of energy metabolic perturbation and cellular distress in the ...
Lars Tomas Hillered, Andreas P Dahlin, Fredrik eClausen, Jiangtao eChu, Jonas eBerquist, Klas eHjort, Per eEnblad, Anders eLewén   +7 more
doaj   +1 more source

Adenosine and glutamate extracellular concentrations and mitogen-activated protein kinases in the striatum of Huntington transgenic mice. Selective antagonism of adenosine A2A receptors reduces transmitter outflow

Neurobiology of Disease, 2004
The basal ganglia and deep layers of cerebral cortex neurodegeneration typically characterize the postmortem brain of Huntington disease (HD) patients.
M. Gianfriddo, A. Melani, D. Turchi, M.G. Giovannini, F. Pedata   +4 more
doaj   +1 more source