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Guidelines on monogenic cerebral small‐vessel disease (cSVD) diagnosis and management are lacking. Endorsed by the Stroke and Neurogenetics Panels of the European Academy of Neurology, a group of experts has provided recommendations on selected monogenic
M. Mancuso+13 more
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How diet affects Alzheimer's disease and small vessel disease
Introduction The number of people with memory disorders is increasing worldwide. Changing certain lifestyle factors can prevent the development of those disorders. Diet is a central factor that can be changed.
Juha Lempiäinen
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Cerebral small vessel disease (CSVD) and multiple sclerosis (MS) are a group of diseases associated with small vessel lesions, the former often resulting from the vascular lesion itself, while the latter originating from demyelinating which can damage ...
Bijia Wang+12 more
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Progress of deep learning in cerebral small vessel disease imaging markers
With the rapid development of artificial intelligence (AI) technology, especially the application of deep learning (DL), the detection and quantitative evaluation of typical imaging markers of small cerebral vascular disease (CSVD) has been accelerated ...
BAI Xue⁃dong +2 more
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Advanced MRI in cerebral small vessel disease [PDF]
Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review summarizes recent developments in advanced neuroimaging of cSVD with a focus on clinical and research applications. In the first section, we highlight how advanced structural imaging techniques, including diffusion magnetic resonance imaging (MRI), enable ...
Hilde van den Brink+2 more
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Progress on the correlation between circle of Willis and cerebral large and small vessel diseases
The circle of Willis constitutes the primary collateral circulation of the brain, exerting a significant influence on the distribution of intracranial blood flow.
FENG Lu, ZHU Yi⁃cheng
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Lacunar Infarction and Small Vessel Disease: Pathology and Pathophysiology [PDF]
Two major vascular pathologies underlie brain damage in patients with disease of small size penetrating brain arteries and arterioles; 1) thickening of the arterial media and 2) obstruction of the origins of penetrating arteries by parent artery intimal ...
Louis R Caplan
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ESO Guideline on covert cerebral small vessel disease [PDF]
‘Covert’ cerebral small vessel disease (ccSVD) is common on neuroimaging in persons without overt neurological manifestations, and increases the risk of future stroke, cognitive impairment, dependency, and death. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist with clinical decisions about ...
Joanna M Wardlaw+15 more
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Large-vessel correlates of cerebral small-vessel disease [PDF]
Our aim was to investigate the relationship of carotid structure and function with MRI markers of cerebral ischemic small-vessel disease.The study comprised 1,800 participants (aged 72.5 ± 4.1 years, 59.4% women) from the 3C-Dijon Study, a population-based, prospective cohort study, who had undergone quantitative brain MRI and carotid ultrasound.
Pierre Boutouyrie+14 more
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Research progress of cerebral small vessel disease associated with immunoinflammatory mechanisms
Cerebral small vessel disease (CSVD) is a type of intracranial vascular disease characterized by recurrent stroke and neurodegenerative progression. The pathogenesis of CSVD is still unclear, and immunoinflammatory mechanisms such as blood⁃brain barrier ...
ZHANG Hai⁃bo, GUO Yan⁃jun
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