Results 31 to 40 of about 2,358 (114)
Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat ischemic stroke. However, there was no clinical evidence of low‐dose CPCGI. We conducted a clinical study to analyze whether the clinical results of low‐dose and standard‐dose CPCGI in patients with ischemic stroke were different.
Ya Chen +8 more
wiley +1 more source
A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials [PDF]
There is no treatment for the myelin loss in multiple sclerosis, ultimately resulting in the axonal degeneration that leads to the progressive phase of the disease.
Agresti, C. +11 more
core +2 more sources
Recent Advances in Homogeneous Metal-Catalyzed Aerobic C–H Oxidation of Benzylic Compounds [PDF]
Csp(3)-H oxidation of benzylic methylene compounds is an established strategy for the synthesis of aromatic ketones, esters, and amides. The need for more sustainable oxidizers has encouraged researchers to explore the use of molecular oxygen.
Domínguez Pérez, Pilar Esther +3 more
core +3 more sources
Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms
Mushrooms are highly nutritious, packed with vitamins, minerals, antioxidants, essential amino acids, and bioactive compounds. They offer various health benefits, including boosting immunity, reducing inflammation, and supporting gut and cardiovascular health. Rich in carbohydrates, quality protein, essential fatty acids, and both soluble and insoluble
Solomon Fitsum +2 more
wiley +1 more source
Structural Analysis of Fungal Cerebrosides [PDF]
Of the ceramide monohexosides (CMHs), gluco- and galactosyl-ceramides are the main neutral glycosphingolipids expressed in fungal cells. Their structural determination is greatly dependent on the use of mass spectrometric techniques, including fast atom bombardment-mass spectrometry, electrospray ionization, and energy collision-induced dissociation ...
Barreto-Bergter, Eliana +2 more
openaire +3 more sources
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
CPCGI Alleviates Neural Damage by Modulating Microglial Pyroptosis After Traumatic Brain Injury
ABSTRACT Background Traumatic brain injury (TBI) is a major global cause of mortality and long‐term disability, with limited therapeutic options. Microglial pyroptosis, a form of programmed cell death associated with inflammation, has been implicated in exacerbating neuroinflammation and secondary injury following TBI.
Lu‐Lu Yu +6 more
wiley +1 more source
Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics [PDF]
Heat shock protein 90 (Hsp90) is a promising cancer drug target as a molecular chaperone critical for stabilization and activation of several of the oncoproteins that drive cancer progression.
Millson, S. H., Piper, P. W.
core +1 more source
Punica granatum (pomegranate) exhibits significant anti‐cancer properties due to its polyphenol‐rich extracts, which modulate signaling pathways involved in inflammation, angiogenesis, and tumor progression. Review highlights its potential to prevent and treat various cancers, including prostate, breast, lung, and colon cancers, by leveraging its ...
Abdur Rauf +11 more
wiley +1 more source
This review explores the nutritional, nutraceutical, and medicinal potential of Cantharellus cibarius, known as the “Golden chanterelle.” Emphasizing its rich composition of bioactive compounds and wide range of health benefits, the review also covers ecological significance, preservation strategies, and potential applications in dietary supplements ...
Ajay Kumar +9 more
wiley +1 more source

