Biomolecules, 2022 Brain aquaporins facilitate the movement of water between the four water compartments: blood, cerebrospinal fluid, interstitial fluid, and intracellular fluid.
José Luis Trillo-Contreras +3 more
doaj +1 more source
Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals. [PDF]
, 2015 BackgroundClinically significant dysregulation of the insulin-like growth factor (IGF) family proteins occurs in HIV-infected individuals, but the details including whether the deficiencies in IGFs contribute to CNS dysfunction are unknown.MethodsWe ...
Choi, Namjong +4 more
core +2 more sources
Cerebrospinal Fluid Protein Changes in Preeclampsia [PDF]
Hypertension, 2018 The molecular mechanisms underlying seizure susceptibility in preeclampsia are unknown. We hypothesized that altered expression of distinct proteins in the cerebrospinal fluid (CSF) may reflect pathophysiological changes in the central nervous system that contribute to the neurological manifestations of severe preeclampsia. We obtained CSF
Towia A. Libermann +7 more
openaire +3 more sources
Mixture of regressions with multivariate responses for discovering subtypes in Alzheimer's biomarkers with detection limits [PDF]
arXiv, 2023 There is no gold standard for the diagnosis of Alzheimer's disease (AD), except from autopsies. Unsupervised learning can provide insight into the pathophysiology of AD. A mixture of regressions can simultaneously identify clusters from multiple biomarkers while accounting for within-cluster demographic effects. Cerebrospinal fluid (CSF) biomarkers for
arxiv
Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children [PDF]
, 2014 Extracellular heat shock protein 72 (Hsp72) is an endogenous danger signal and potential biomarker for critical illness in children. We hypothesized that elevated levels of extracellular Hsp72 in the cerebrospinal fluid (CSF) of children with suspected ...
Kernie, Steven G. +5 more
core +1 more source
International Journal of Hypertension, 2013 The aim of the present work is to analyze the cerebrospinal fluid proteomic profile, trying to find possible biomarkers of the effects of hypertension of the blood to CSF barrier disruption in the brain and their participation in the cholesterol and β ...
Ibrahim González-Marrero +8 more
doaj +1 more source
Directional flow in perivascular networks: Mixed finite elements for reduced-dimensional models on graphs [PDF]
arXiv, 2023 The flow of cerebrospinal fluid through the perivascular spaces of the brain is believed to play a crucial role in eliminating toxic waste proteins. While the driving forces of this flow have been enigmatic, experiments have shown that arterial wall motion is central.
arxiv
Kinetics-like equation for cerebrospinal fluid-blood diffusion models
Revista Cubana de Investigaciones Biomédicas, 2020 Introduction: The diffusion of proteins from the blood to the cerebrospinal fluid is influenced by its molecular weight and by the intrinsic properties and biological properties of the protein. Objective: Determinate the diffusion of new proteins as they
José Alejandro Rodríguez-Pérez +6 more
doaj
Cerebrospinal fluid endo-lysosomal proteins as potential biomarkers for Huntington's disease.
PLoS ONE, 2020 Molecular markers derived from cerebrospinal fluid (CSF) represent an accessible means of exploring the pathobiology of Huntington's disease (HD) in vivo.
Alexander J Lowe +7 more
doaj +1 more source
Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease [PDF]
, 2005 Background: S-100B and tau protein have a high differential diagnostic potential for the diagnosis of Creutzfeldt-Jakob disease (CJD). So far there has been only limited information available about the dynamics of these parameters in the cerebrospinal ...
Barbara Ciesielczyk +18 more
core +1 more source