Results 251 to 260 of about 45,269 (354)

Survival outcomes and prognostic factors of gastric carcinoma with neuroendocrine differentiation

International Journal of Cancer, EarlyView.
What's New? Although gastric carcinoma with neuroendocrine differentiation (GCNED) is associated with more aggressive features than conventional GC, its prognosis and survival remain poorly defined. To better understand survival patterns, the authors of the present study examined clinicopathological and prognostic features of GCNED patients following ...
Jinjin Li, Chenglong Wang, Yifan Shen, Zhen Huang, Jun Zhang, Siqi Rao, Youde Cao, Jiang Min   +7 more
wiley   +1 more source

Hypertension Increases Susceptibility to Lead-Induced Microglial Polarization via ANT1-Mediated Mitochondrial DNA/cGAS/STING Signaling. [PDF]

Research (Wash D C)
Zhao Y, Shi F, Hao H, Wang Z, Li J, Liu B, Niu Y, Wang W, Zhang Y.   +8 more
europepmc   +1 more source

Extracellular vesicle‐based vaccines and immunotherapeutics for treatment of cancer

Interdisciplinary Medicine, EarlyView.
This review highlights the innovative value of extracellular vesicles (EVs) as cancer vaccines and immunotherapy carriers. EVs have natural advantages such as low immunogenicity, high biocompatibility, stability, and precise targeting, enabling efficient delivery of tumor antigens (e.g., HER2, AFP) and immune stimulants (e.g., TLR ligands, cytokines ...
Lejia Tan, Haonan Xing, Fang Fang, Yuanyu Huang, Mei Lu   +4 more
wiley   +1 more source

Activation of cGAS-STING signaling in senescent cells promotes the aging process by remodeling the functions of the immune system. [PDF]

Biogerontology
Salminen A, Kaarniranta K, Kauppinen A.
europepmc   +1 more source

CGA General Half [PDF]

IEEE Annals of the History of Computing, 2019
openaire   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

cGAS-STING: From immunology and oncology view. [PDF]

Chin Med J (Engl)
Liu X, Ding C, Lu J, Zhang N.
europepmc   +1 more source

Advances of cGAS

Advances in Marine Sciences, 2017
openaire   +1 more source

STING activation by teniposide: a potential direct mechanism beyond cGAS stimulation. [PDF]

Front Immunol
Arranz-Herrero J, Marquez-Cantudo L, Rius-Rocabert S, Buey RM, Velazquez-Campoy A, Tur-Planells V, Garcia-Sastre A, Miorin L, de Pascual-Teresa B, Coderch C, Nistal-Villan E.   +10 more
europepmc   +1 more source

Impact of Baseline Nutritional Status, Psychological Health, Fatigue, and Insomnia on Outcomes of Immune Checkpoint Inhibitors in Advanced Non‐Small Cell Lung Cancer: A Retrospective Cohort Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the impact of pretreatment nutritional status, psychological health, fatigue, and insomnia on outcomes of immune checkpoint inhibitors (ICIs) monotherapy in patients with advanced non‐small cell lung cancer (NSCLC). A total of 80 patients with stage IV NSCLC were enrolled.
Yu‐Xuan Zhu, Yuan‐Yuan Zhang, Xiu‐Juan Jiang   +2 more
wiley   +1 more source