Results 61 to 70 of about 31,976 (243)
Securing route optimisation in NEMO [PDF]
, 2005 Third International Symposium on Modeling and Optimization in Mobile, Ad Hoc,and Wireless Networks. 4-6 April 2005. Riva del Garda, Trentino, ItalyThe network mobility (NEMO) basic support protocol enables mobile networks to change their point of ...
Bagnulo Braun, Marcelo Gabriel +3 more
core +3 more sources
Advanced Science, EarlyView.Small cell lung cancer (SCLC) harbors high molecular heterogeneity. Using a new liquid biopsy assay, SCLC subtypes can be identified by measuring mRNA of subtype transcription factors (ASCL1, POU2F3, and NEUROD1) in exosome‐rich extracellular vesicles. Combining with Delta‐like ligand 3 (DLL3) mRNA in exosomes and its membrane protein in extracellular ...
Hong Li +27 more
wiley +1 more source
Natural Compounds as Beneficial Antioxidant Agents in Neurodegenerative Disorders: A Focus on Alzheimer’s Disease [PDF]
, 2019 The positive role of nutrition in chronic neurodegenerative diseases (NDs) suggests that dietary interventions represent helpful tools for preventing NDs.
Antonella Amato +2 more
core +1 more source
Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range
Advanced Science, EarlyView.ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen +8 more
wiley +1 more source
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes [PDF]
, 2017 Many human cells can sense the presence of exogenous DNA during infection though the cytosolic DNA receptor cyclic GMP-AMP synthase (cGAS), which produces the second messenger cyclic GMP-AMP (cGAMP).
A Ablasser +52 more
core +5 more sources
EMBO reports, 2017 Recognition of foreign nucleic acids by the immune system is essential to host protection against many viral and bacterial infections. It relies on the capacity of innate immune sensors to selectively distinguish self‐ and non‐self‐nucleic acids, on the basis of a variety of parameters including base modifications, sequence composition, length or ...
Michael P. Gantier, Michael P. Gantier
openaire +3 more sources
Advanced Science, EarlyView.PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu +22 more
wiley +1 more source
Paediatric obsessive-compulsive disorder and depressive symptoms: clinical correlates and CBT treatment outcomes. [PDF]
, 2014 Depression frequently co-occurs with paediatric obsessive-compulsive disorder (OCD), yet the clinical correlates and impact of depression on CBT outcomes remain unclear.
AM Garcia +49 more
core +1 more source
Advanced Science, EarlyView.The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang +9 more
wiley +1 more source
The polyphenolic and hydroxycinnamate contents of whole coffee fruits from China, India and Mexico [PDF]
, 2013 Air dried whole coffee fruits, beans and husks from China, India and Mexico were analysed for their chlorogenic acids (CGA), caffeine, and polyphenolic content. Analysis was by HPLC and Orbitrap exact mass spectrometry.
Combet, E. +4 more
core +1 more source