Results 111 to 120 of about 50,213 (312)

Receptors mediating CGRP‐induced relaxation in the rat isolated thoracic aorta and porcine isolated coronary artery differentiated by hα CGRP_8–37 [PDF]

, 1999
F M Wisskirchen, David W. Gray, Ian Marshall   +2 more
openalex   +1 more source

PLGA Containing Human Adipose‐Derived Stem Cell‐Derived Extracellular Vesicles Accelerates the Repair of Alveolar Bone Defects via Transfer of CGRP [PDF]

, 2022
Yang� Yang, Bo Zhang, Yufan Yang, Bibo Peng, Rui Ye   +4 more
openalex   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

Health Technology Assessment: Evaluation of 8 CGRP-Targeted Therapy Drugs for the Treatment of Migraine

Drug Design, Development and Therapy
Mengyi Li, Siyong Huang, Jiabao Li, Xiao Hu, Jisheng Chen Key Specialty of Clinical Pharmacy, the First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, People’s Republic of ChinaCorrespondence: Jisheng Chen, Key Specialty of ...
Li M, Huang S, Li J, Hu X, Chen J
doaj  

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Probabilistic Monads, Domains and Classical Information

, 2012
Shannon's classical information theory uses probability theory to analyze channels as mechanisms for information flow. In this paper, we generalize results of Martin, Allwein and Moskowitz for binary channels to show how some more modern tools ...
Mislove, Michael
core   +2 more sources

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

CGRP Plasma Levels Correlate with the Clinical Evolution and Prognosis of Hospitalized Acute COVID-19 Patients [PDF]

, 2022
Manuela Rizzi, Stelvio Tonello, Francesca Morani, Eleonora Rizzi, Giuseppe Francesco Casciaro, Erica Matino, Martina Costanzo, Erika Zecca, Alessandro Croce, Anita Rebecca Pedrinelli, Veronica Vassia, Raffaella Landi, Venkata Ramana Mallela, Davide D’Onghia, Rosalba Minisini, Mattia Bellan, Luigi Mario Castello, Francesco Gavelli, Gian Carlo Avanzi, Filippo Patrucco, Mario Pirisi, Donato Colangelo, Pier Paolo Sainaghi   +22 more
openalex   +1 more source

The Responses to CGRP in the Territory of the Posterior Cerebral Artery in Migraine [PDF]

, 2022
Darja Visočnik, Marjan Zaletel, Matija Zupan, Bojana Žvan   +3 more
openalex   +1 more source

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

The FEBS Journal, EarlyView.
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson, Isabel Fernandes Parreira, Ruth H. Thompson, Mark O. Collins, Jonathan G. Shaw, Luke R. Green   +5 more
wiley   +1 more source