Results 111 to 120 of about 48,956 (312)

The Calcitonin/Calcitonin Gene-Related Peptide Family in Invertebrate Deuterostomes

open access: yesFrontiers in Endocrinology, 2018
Calcitonin (CT)/CT gene-related peptide (CGRP) family peptides (CT/CGRP family peptides) including CT, CGRP, adrenomedullin, amylin, and CT receptor-stimulating peptide have been identified from various vertebrates and perform a variety of important ...
Toshio Sekiguchi
doaj   +1 more source

Probabilistic Monads, Domains and Classical Information

open access: yes, 2012
Shannon's classical information theory uses probability theory to analyze channels as mechanisms for information flow. In this paper, we generalize results of Martin, Allwein and Moskowitz for binary channels to show how some more modern tools ...
Mislove, Michael
core   +2 more sources

Osteochondrosis in horses: An overview of genetic and other factors

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez   +2 more
wiley   +1 more source

The Role of Calcitonin Gene Related Peptide (CGRP) in Neurogenic Vasodilation and Its Cardioprotective Effects

open access: yesFrontiers in Physiology, 2018
Calcitonin gene-related peptide (CGRP) is a highly potent vasoactive peptide released from sensory nerves, which is now proposed to have protective effects in several cardiovascular diseases.
Zizheng Kee, Xenia Kodji, Susan D. Brain
doaj   +1 more source

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

open access: yesThe FEBS Journal, EarlyView.
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson   +5 more
wiley   +1 more source

Can serum neuropeptide levels help diagnose pediatric migraine? A prospective case–control study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The objective of this study was to examine the serum levels of vasoactive neuropeptides (calcitonin gene‐related peptide [CGRP], pituitary adenylate cyclase‐activating peptide‐38 [PACAP‐38], substance P [SP], and vasoactive intestinal peptide [VIP], which have been linked to the pathophysiology of migraine in adults) in pediatric ...
Sibğatullah Ali Orak   +8 more
wiley   +1 more source

Efficacy and Safety of Rimegepant 75 mg Oral Tablet, a CGRP Receptor Antagonist, for the Acute Treatment of Migraine: A Randomized, Double-Blind, Placebo-Controlled Trial

open access: yesJournal of Pain Research
Richard B Lipton,1 Alexandra Thiry,2 Beth A Morris,3 Robert Croop3 1Department of Neurology and the Montefiore Headache Center, Albert Einstein College of Medicine, Bronx, NY, USA; 2Biostatistics, Pfizer, Inc., New York, NY, USA; 3Clinical Operations (BM)
Lipton RB, Thiry A, Morris BA, Croop R
doaj  

Capsaicin-Induced Ca2+ Influx and Constriction of the Middle Meningeal Artery [PDF]

open access: yes, 2014
Research in the past on transient receptor potential cation channel subfamily V member 1 (TRPV1) has been limited to mainly nervous tissue TRPV1 because of the channel’s role in pain perception.
Koide, Masayo   +5 more
core   +1 more source

Effectiveness and tolerability of liraglutide as add‐on treatment in patients with obesity and high‐frequency or chronic migraine: A prospective pilot study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess whether glucagon‐like‐peptide‐1 receptor (GLP‐1R) agonists could serve as a novel prophylactic treatment for migraine in patients with obesity. Background Increased intracranial pressure (ICP) is speculated to play a role in migraine mechanisms, as chronic migraine and idiopathic intracranial hypertension without ...
Simone Braca   +6 more
wiley   +1 more source

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