Results 131 to 140 of about 50,213 (312)

Reasons for patient reluctance to take preventive medications for migraine: Results of the OVERCOME (US) study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to evaluate patient reasons for nonadoption of migraine‐preventive medications. Despite clear recommendations and eligibility criteria for migraine‐preventive treatment by the American Headache Society and the availability of these treatments, many people with migraine are not taking appropriate ...
Jessica Ailani, Rose Okonkwo, Elizabeth Johnston, Helen Hochstetler, Betzaida Martinez, Anthony Zagar, Robert A. Nicholson, Bert B. Vargas, E. Jolanda Muenzel, Richard B. Lipton   +9 more
wiley   +1 more source

Retrospective analysis of the tolerability and effectiveness of rimegepant for the acute treatment of migraine in adolescents

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aims to evaluate the tolerability and effectiveness of the off‐label use of rimegepant as acute migraine treatment in adolescents. Background Calcitonin gene‐related peptide (CGRP) levels are elevated during migraine attacks.
Konstantinos Tourlas, Sruthi Ilangovan, Chelsea White, Samantha L. Irwin, Sara Pavitt   +4 more
wiley   +1 more source

Synaptic and neurochemical features of calcitonin gene-related peptide containing neurons in the rat accessory optic nuclei. [PDF]

, 1999
Within the rodent visual system, calcitonin gene-related peptide (CGRP) is selectively expressed in neurons in the accessory optic nuclei (AON), including the dorsal terminal nucleus (DTN), lateral terminal nucleus (LTN) and medial terminal nucleus (MTN).
Giolli, RA, Ribak, CE, Yan, XX, Zhou, J
core  

Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism [PDF]

, 2010
Ernst ter Haar, Christopher M. Koth, Norzehan Abdul-Manan, Lora Swenson, Joyce T. Coll, Judith A. Lippke, Christopher A. Lepre, Miguel García‐Guzmán, Jonathan M. Moore   +8 more
openalex   +1 more source

Optogenetic stimulation of the motor cortex alleviates neuropathic pain in rats of infraorbital nerve injury with/without CGRP knock-down [PDF]

, 2020
Jaisan Islam, Elina KC, Byeong Ho Oh, Soochong Kim, Sang‐Hwan Hyun, Young Seok Park   +5 more
openalex   +1 more source

Sex differences in the effects of calcitonin gene-related peptide signaling on migraine-like behavior in animal models: a narrative review

Frontiers in Neurology
Migraine is a common neurological disorder with a typical onset in adolescence or early adulthood. Migraine is three times more common in women than men, but the definitive cause underlying the observed disparity is not fully understood.
Lakeisha A. Lewter, Rachel L. Arnold, Nina B. Narosov, Gregory Dussor, Benedict J. Kolber   +4 more
doaj   +1 more source

Efficacy and safety of rimegepant for the acute treatment of migraine in Black or African American adults: A post hoc pooled subgroup analysis from three randomized, placebo‐controlled clinical trials

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This post hoc subgroup analysis was conducted using pooled data from three US‐based clinical trials to compare efficacy and safety of rimegepant 75 mg versus placebo in acute migraine in adults who are Black or African American.
Larry Charleston IV, Cynthia E. Armand, Teshamae S. Monteith, Hope L. O'Brien, Chandra C. Abbott, Glenn C. Pixton, Terence Fullerton   +6 more
wiley   +1 more source

Ion channels in migraine disorders [PDF]

, 2018
Pietrobon, Daniela
core   +1 more source

POSA28 Reductions in Migraine and Headache Days After Initiating Fremanezumab for Patients with Migraine and Prior Use of Another Monoclonal Antibody Targeting the CGRP Pathway in a US Real-World Setting [PDF]

, 2022
Martin Drießen, Oscar Patterson‐Lomba, Fan Mu, Stephen Thompson, Michael J. Seminerio, Karen Carr, R Sun, Todor Totev, Eunsil Yim, Rajeev Ayyagari, Joshua M. Cohen   +10 more
openalex   +1 more source

Integrating gepants into clinical practice for the acute treatment of migraine

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess the role of small‐molecule calcitonin gene–related peptide receptor antagonists (gepants) in the acute treatment of migraine, particularly in relation to triptan treatments. Background Triptans have established efficacy and are widely prescribed for the acute treatment of migraine.
Richard B. Lipton, David W. Dodick, Linda Davis, Stephanie J. Nahas, Peter J. Goadsby   +4 more
wiley   +1 more source