Results 131 to 140 of about 43,468 (306)

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

Effectiveness and tolerability of galcanezumab for migraine prevention in patients ≥65 years: A real‐life multicenter study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary This study shows that galcanezumab is equally effective and well‐tolerated in patients aged 65 and older as in younger patients, with a higher proportion of excellent responders in older patients. Despite having more baseline headache days, older patients responded well to the treatment, with age being linked to better outcomes ...
Julia Peris‐Subiza   +27 more
wiley   +1 more source

Sex differences in the effects of calcitonin gene-related peptide signaling on migraine-like behavior in animal models: a narrative review

open access: yesFrontiers in Neurology
Migraine is a common neurological disorder with a typical onset in adolescence or early adulthood. Migraine is three times more common in women than men, but the definitive cause underlying the observed disparity is not fully understood.
Lakeisha A. Lewter   +4 more
doaj   +1 more source

Impact of anti-CGRP monoclonal antibodies on migraine attack accompanying symptoms: A real-world evidence study [PDF]

open access: hybrid, 2023
Alicia Alpuente   +5 more
openalex   +1 more source

Comprehensive assessment of erenumab efficacy in participants with high‐frequency episodic migraine with at least one previously failed preventive treatment: The EMBRACE study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To evaluate the effect of erenumab treatment beyond monthly migraine days in patients with high‐frequency episodic migraine who did not respond to at least one previous migraine preventive treatment. Background Reduction in monthly migraine days has been the efficacy standard for migraine preventive treatments; however, it does not ...
Gabriel Paiva da Silva Lima   +11 more
wiley   +1 more source

TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Background The transient receptor potential melastatin 3 (TRPM3) ion channel has been implicated in sensory modulation and pain transmission and may contribute to migraine pathophysiology through calcitonin gene‐related peptide (CGRP) release in the trigeminovascular system. This study aimed to investigate TRPM3 activation and its role in CGRP
Philip V. Reducha   +9 more
wiley   +1 more source

CGRP Plasma Levels Correlate with the Clinical Evolution and Prognosis of Hospitalized Acute COVID-19 Patients [PDF]

open access: gold, 2022
Manuela Rizzi   +22 more
openalex   +1 more source

First successful protocol for desensitization to eptinezumab

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Eptinezumab is an anti‐calcitonin gene‐related peptide monoclonal antibody used for migraine prevention. During clinical trials, hypersensitivity to eptinezumab was described without a clear underlying mechanism. To determine if the reaction was immunoglobulin E–mediated, the team of Nice University Hospital (Nice, France) performed
Benoit Gerard   +8 more
wiley   +1 more source

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