Results 171 to 180 of about 50,213 (312)

Stimulation of rat cranial dura mater with potassium chloride causes CGRP release into the cerebrospinal fluid and increases medullary blood flow

, 2017
Mária Dux, Christine Will, Mirjam Eberhardt, Michael J. M. Fischer, Karl Meßlinger   +4 more
openalex   +1 more source

Safety of anti-CGRP monoclonal antibodies in patients with migraine during the COVID-19 pandemic: Present and future implications

, 2021
Edoardo Caronna, Victor J Gallardo, Alicia Alpuente, Marta Torres‐Ferrús, N.M. Sánchez-Mateo, J. Viguera Romero, A.C. López-Veloso, A. López-Bravo, Ana Beatriz Gago‐Veiga, Pablo Irimia, J. Porta‐Etessam, Sonia Santos Lasaosa, Patricia Pozo‐Rosich   +12 more
openalex   +1 more source

Glymphatic System Dysfunction in Central Nervous System Diseases

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Glymphatic Dysfunction in Neurological Disorders: The glymphatic system is a brain‐wide clearance system that removes neurotoxic waste via AQP4‐mediated CSF‐ISF exchange. Dysfunction through AQP4 mislocalization, BBB injury, and inflammation annihilates clearance and causes acute (stroke, TBI) and chronic disease.
Anwar Zahran, Omar Abu‐Khazneh, Mohammad Bdair, Orabi Hajjeh, Mohammed AbuBaha, Waseem Shehadeh, Ameer Awashra, Ibrahim Alazizi, Raya Fuqha, Sakeena Saife, Hasan Fuqha, Fathi Milhem, Husam Hamshary, Dana Abuzahra, Umar Shuaib   +14 more
wiley   +1 more source

Optimization of azepanone calcitonin gene-related peptide (CGRP) receptor antagonists: Development of novel spiropiperidines

, 2009
Christopher S. Burgey, Craig M. Potteiger, James Z. Deng, Scott D. Mosser, Christopher Salvatore, Sean Yu, Shane Roller, Stefanie A. Kane, Joseph P. Vacca, Theresa M. Williams   +9 more
openalex   +1 more source

CGRP and Adrenomedullin Modulate Synaptic Transmission in Purkinje Cells [PDF]

, 2001
Heather Cater, David R. Poyner, Nicholas A. Hartell   +2 more
openalex   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, Volume 15, Issue 3, March 2026.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

Anti-CGRP receptor antibodies do not modulate trigeminal pain processing: indication for distinct mechanisms of CGRP pathway blockade. [PDF]

J Headache Pain
Peng KP, Basedau H, Messlinger K, May A.
europepmc   +1 more source

Ingestion-activated CGRP neurons control learning but not satiety [PDF]

Brooke C. Jarvie, Anagh Ravi, Rhea Nanavati, Longhui Qui, Truong Ly, Jun Yeop Oh, Olivia Barnhill, Zachary A. Knight   +7 more
openalex   +1 more source

Differential Alterations in Offset Analgesia and Conditioned Pain Modulation in Fibromyalgia: Evidence for Distinct Central Dysregulation

European Journal of Pain, Volume 30, Issue 3, March 2026.
ABSTRACT Background Chronic pain often involves abnormalities in central pain processing. Two commonly used experimental methods for central pain modulation are conditioned pain modulation (CPM) and offset analgesia (OA). However, it is uncertain how similar the underlying processes they measure are.
Yara Agbaria, Giris Jacob, Raz Preger, Jacob N. Ablin, Valerie Aloush, Haggai Sharon   +5 more
wiley   +1 more source

Late-Onset Ocular Myasthenia Gravis-Like Symptoms During Erenumab Therapy for Chronic Migraine: A Case Report. [PDF]

Biologics
Qaqish A, Al Anber A, Abdelhafez G.
europepmc   +1 more source