Results 81 to 90 of about 50,213 (312)

Efficacy of fremanezumab in patients with chronic migraine and concomitant depression

open access: yesКлинический разбор в общей медицине
Background. Migraine is a common chronic disorder that ranks third in the disability-adjusted life years among nervous system disorders. It is well known that migraine is strongly associated with the depression/anxiety disorders; there is overwhelming ...
A.Y. Timokhovich   +2 more
doaj   +1 more source

Deficiency of Calcitonin Gene-Related Peptide Affects Macrophage Polarization in Osseointegration

open access: yesFrontiers in Physiology, 2020
Macrophages have been described as a critical cell population regulating bone regeneration and osseointegration, and their polarization phenotype is of particular importance.
Ying Yuan   +5 more
doaj   +1 more source

CGRP protects bladder smooth muscle cells stimulated by high glucose through inhibiting p38 MAPK pathway in vitro

open access: yesScientific Reports, 2021
This study aimed to explore the effect of calcitonin gene-related peptide (CGRP) on bladder smooth muscle cells (BSMCs) under high glucose (HG) treatment in vitro. BSMCs from Sprague–Dawley rat bladders were cultured and passaged in vitro.
Jun Xue   +6 more
doaj   +1 more source

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray   +8 more
wiley   +1 more source

Nasal Air‐Jet Sensitivity Differentiates Empty Nose Syndrome and Turbinate Reduction Patients: A Pilot Study

open access: yesThe Laryngoscope, EarlyView.
This prospective pilot study aims to compare nasal mucosal sensitivity to air‐jet stimuli between ENS patients and patients who underwent septoplasty/turbinate reduction (septo‐turb) surgery, but without ENS symptoms. The ENS group had a significantly higher (less sensitive) threshold than the septo‐turb group for the septum opposing the center of the ...
Kanghyun Kim   +8 more
wiley   +1 more source

Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]

open access: yes, 2017
The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core   +3 more sources

Ubrogepant in the Acute Management of Migraine: A Narrative Review

open access: yesJournal of Pain Research, 2021
Chia-Chun Chiang,1 Juliana H VanderPluym2 1Department of Neurology, Mayo Clinic, Rochester, MN, USA; 2Department of Neurology, Mayo Clinic, Scottsdale, AZ, USACorrespondence: Juliana H VanderPluym Email vanderpluym.juliana@mayo.eduAbstract: Ubrogepant is
Chiang CC, VanderPluym JH
doaj  

The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares   +2 more
wiley   +1 more source

Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn [PDF]

open access: yes, 2014
Background: Gastrin-releasing peptide (GRP) and its receptor have been shown to play an important role in the sensation of itch. However, although GRP immunoreactivity has been detected in the spinal dorsal horn, there is debate about whether this ...
Gutierrez-Mecinas, Maria   +2 more
core   +1 more source

A Novel Rat Model to Study Postsurgical Pain After Joint Replacement Surgery

open access: yesJournal of Pain Research, 2022
Naoki Aoyama, Masashi Izumi, Toru Morimoto, Hiroyuki Wada, Junpei Dan, Yusuke Kasai, Yoshinori Satake, Koji Aso, Masahiko Ikeuchi Department of Orthopedic Surgery, Kochi Medical School, Kochi University, Nankoku, JapanCorrespondence: Masashi Izumi ...
Aoyama N   +8 more
doaj  

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