Results 81 to 90 of about 48,956 (312)
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine [PDF]
, 2004 Background: Calcitonin gene–related peptide (CGRP) may have a causative role in migraine. We therefore hypothesized that a CGRP-receptor antagonist might be effective in the treatment of migraine attacks.
Diener, H.-C. +7 more
core +1 more source
Associations Between Fatty Acid Levels in Human Blood and Trigeminovascular Tissues
Lipids, EarlyView.ABSTRACT Omega‐3 and omega‐6 polyunsaturated fatty acids (PUFAs) are precursors to oxylipins that modulate pain and inflammation. We previously demonstrated that (1) a dietary intervention increasing omega‐3 and reducing omega‐6 PUFAs alters the concentration of these oxylipin precursors in blood, and (2) these changes are associated with reduced ...
Daisy Zamora +8 more
wiley +1 more source
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
Medicine Bulletin, EarlyView.ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
wiley +1 more source
Projection neurons in lamina III of the rat spinal cord are selectively innervated by local dynorphin-containing excitatory neurons [PDF]
, 2012 Large projection neurons in lamina III of the rat spinal cord that express the neurokinin 1 receptor are densely innervated by peptidergic primary afferent nociceptors and more sparsely by low-threshold myelinated afferents. However, we know little about
Baseer, N. +5 more
core +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Introduction and Objectives Targeted radiofrequency (RF) therapy is a promising treatment for overactive bladder (OAB), aiming to modulate autonomic nerve pathways for symptom control. This cadaveric study focuses on identifying areas of high nerve density in the bladder and corresponding vaginal wall (AVW) to support RF use in a minimally ...
Gamal Ghoniem +2 more
wiley +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Despite modern bladder management methods, lower and upper urinary tract complications still contribute significantly to morbidity and diminished quality of life in persons with spinal cord injuries (SCI). Neurogenic overactive bladders often develop after SCI and this can result in loss of compliance, with concomitant urinary tract ...
Noor Al‐Khayat +5 more
wiley +1 more source
Ubrogepant in the Acute Management of Migraine: A Narrative Review
Journal of Pain Research, 2021 Chia-Chun Chiang,1 Juliana H VanderPluym2 1Department of Neurology, Mayo Clinic, Rochester, MN, USA; 2Department of Neurology, Mayo Clinic, Scottsdale, AZ, USACorrespondence: Juliana H VanderPluym Email vanderpluym.juliana@mayo.eduAbstract: Ubrogepant is
Chiang CC, VanderPluym JH
doaj
State of the art in the management of migraine-A response to the American College of Physicians migraine preventive treatment guideline. [PDF]
HeadacheHeadache: The Journal of Head and Face Pain, Volume 65, Issue 9, Page 1653-1656, October 2025.
Charles AC, Tepper SJ, Ailani J.
europepmc +2 more sources
Sensory Neuroscience, EarlyView.ABSTRACT Sensory neuron disorders, such as peripheral neuropathies and trigeminal neuralgia, cause chronic pain and sensory dysfunction; however, regenerative treatments are limited. Human pluripotent stem cells (hPSCs) provide a powerful platform to model these diseases by generating functional sensory neuron subtypes, including nociceptors and ...
Pushpanathan Muthuirulan +3 more
wiley +1 more source
Neurology InternationalCalcitonin gene-related peptide monoclonal antibodies (CGRP mAbs) have shown promising effectiveness in migraine management compared to other preventative treatment options.
Reem Suliman +9 more
doaj +1 more source