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Chagas’ disease is a protozoan infection caused by Trypanosoma cruzi and is mainly acquired by vectorial transmission in endemic areas, when infected excreta of Triatominae bugs are inoculated into the sting site or neighbouring mucous membranes of the victim.
Marin-Neto, José Antonio +2 more
openaire +5 more sources
Protective immunity against Trypanosoma cruzi [PDF]
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel +2 more
core +1 more source
AbstractChagas' disease is caused by a protozoan parasite, Trypanosoma cruzi, that is transmitted to humans through the feces of infected bloodsucking insects in endemic areas of Latin America, or occasionally by nonvectorial mechanisms, such as blood transfusion.
A, Rassi, A, Rassi, W C, Little
openaire +2 more sources
Risk of Zika virus-associated birth defects in congenital confirmed cases in the Brazilian Amazon
Objective. To establish the risk of microcephaly in neonates born to women infected with ZIKV during pregnancy. Methods. A cohort of laboratory-confirmed ZIKV cases of congenital infections (109 mothers infected during pregnancy and 101 newborns) among ...
Consuelo S de Oliveira +15 more
doaj +1 more source
Histopathological lesions of congenital Zika syndrome in newborn squirrel monkeys
The absence of an adequate animal model for studies has limited the understanding of congenital Zika syndrome (CZS) in humans during the outbreak in America.
Bianca Nascimento de Alcantara +17 more
doaj +1 more source
Clinical features of Chagas disease progression and severity
Summary Chagas disease, the most common form of nonischaemic cardiomyopathy globally, is one of the leading causes of morbidity and mortality in Latin America.
M. C. P. Nunes +4 more
semanticscholar +1 more source
Key Points Question What is the risk of developing cardiomyopathy among patients with the acute phase of Chagas infection or the indeterminate chronic form of Chagas disease?
S. Chadalawada +15 more
semanticscholar +1 more source
The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America [PDF]
It is estimated that between 8000 and 15 000 Trypanosoma cruzi infected babies are born every year to infected mothers in Chagas disease endemic countries. Currently, poor access to and performance of the current diagnostic algorithm, based on microscopy
Cruz, Israel +7 more
core +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Introdução/Objetivos: As infecções respiratórias agudas (IRA) constituem um importante problema em saúde pública, especialmente aquelas desencadeadas pelo Vírus Sincicial Respiratório (VSR), um dos principais agentes virais associados à doença grave na ...
Luana Soares Barbagelata +12 more
doaj +1 more source

