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First described by Carlos Justiniano Ribeiro Chagas (1879-1934) in 1909, Chagas disease (CD) or American trypanosomiasis is caused by the protozoan parasite Trypanosoma cruzi.
Vera Demarchi Aiello +1 more
doaj +4 more sources
Circulating Trypanosoma cruzi load and major cardiovascular outcomes in patients with chronic Chagas cardiomyopathy: a prospective cohort study [PDF]
To analyse the effect of parasite load assessed by quantitative reverse transcription PCR (RT‐qPCR) in serum on the prognosis of patients with chronic Chagas cardiomyopathy (CCM) after a 2‐year follow‐up.
Luis Eduardo Echeverría +7 more
openalex +2 more sources
Clinical Presentations of Chagas Cardiomyopathy
Chronic Chagas cardiomyopathy (CCC) is the most common cause of nonischemic cardiomyopathy in endemic Latin American countries. Immigrants to the United States suffer from this disease, but it is underrecognized.
Malik Shehadeh, Ana Barac, Rachel Marcus
doaj +4 more sources
Background Risk stratification of Chagas disease patients in the limited‐resource setting would be helpful in crafting management strategies. We developed a score to predict 2‐year mortality in patients with Chagas cardiomyopathy from remote endemic ...
Claudia Di Lorenzo Oliveira +13 more
doaj +2 more sources
Echocardiographic predictors of mortality in heart failure from Chagas cardiomyopathy: Refining risk stratification with speckle-tracking echocardiography [PDF]
Background: Chagas cardiomyopathy is a major cause of mortality in endemic regions, predicted primarily by left ventricular (LV) systolic function. Speckle-tracking echocardiography (STE)–derived strain is a sensitive tool for assessing ventricular ...
Marcelo Alves Maia +10 more
doaj +2 more sources
Chagas cardiomyopathy is caused by Trypanosoma cruzi (Tc). We identified two candidate antigens (TcG2 and TcG4) that elicit antibodies and T cell responses in naturally infected diverse hosts.
Nandadeva Lokugamage +4 more
doaj +2 more sources
Background: Cardiac rehabilitation exerts anti-inflammatory effect on several cardiovascular diseases; however, these effects were not described for Chagas cardiomyopathy, which is associated with pro-inflammatory imbalance.
Luiz Fernando Rodrigues Junior +7 more
doaj +2 more sources
Stroke in Chagas disease: from pathophysiology to clinical practice [PDF]
Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern.
Thaís Aparecida Reis Lage +6 more
doaj +1 more source
Association of chronic Chagas cardiomyopathy stages with obstructive sleep apnea and excessive daytime sleepiness: a cross-sectional study. [PDF]
Cruz LF +9 more
europepmc +3 more sources
Cardiac resynchronization therapy in chronic Chagas cardiomyopathy: A systematic review and single-arm meta-analysis. [PDF]
Ferreira Felix I +11 more
europepmc +3 more sources

