Results 41 to 50 of about 12,753 (211)

Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]

, 2018
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro, Cancrini, Gabriella, Gabrielli, Simona, Gamboa, Herlan, Macchioni, Fabio, Rojas, Patricia, Rojo, David, Roselli, Mimmo, Spinicci, Michele, Totino, Valentina   +9 more
core   +2 more sources

Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]

, 2018
Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo, Hejchman, Elżbieta, Hernández Rodríguez, Vanessa, Pinto Martinez, Andrea, Rodríguez Durán, Jessica Jenireth   +4 more
core   +1 more source

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model [PDF]

, 2016
Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been ...
Andrada, Marta Cecilia, Aoki, Maria del Pilar, Cabalén, María Eugenia, Cabral, Maria Fernanda, Cano, Roxana Carolina, Gea, Susana, Onofrio, Luisina Inés, Ponce, Nicolás Eric, Sanmarco, Liliana Maria   +8 more
core   +4 more sources

Elevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension. [PDF]

, 2015
Pulmonary arterial hypertension (PAH) can be idiopathic or secondary to autoimmune diseases, and it represents one of the most threatening complications of systemic sclerosis (SSc).
Alessandri, Cristiano, Badagliacca, Roberto, Pendolino, Monica, Poscia, Roberto, Riccieri, Valeria, Sciarra, Iliana, Stefanantoni, Katia, Valesini, Guido, Vasile, M, Vizza, Carmine Dario   +9 more
core   +2 more sources

A Novel Predictive Score to Identify the Necessity for Epicardial Ventricular Tachycardia Ablation: EPI‐VT‐Score

Journal of Cardiovascular Electrophysiology, Volume 36, Issue 11, Page 2870-2877, November 2025.
The novel EPI‐VT‐Score accurately predicts the need for epicardial VT ablation using simple clinical, echocardiographic and ECG variables, optimizing patient selection and procedural outcomes. ABSTRACT Background Epicardial ventricular tachycardia (VT) ablation is a therapeutic option for drug‐refractory VT, particularly when endocardial ablation fails
Moneeb Khalaph, Denise Guckel, Nadica Trajkovska, Maxim Didenko, Mustapha El Hamriti, Martin Braun, Guram Imnadze, Philip Lucas, Thomas Fink, Vanessa Sciacca, Sebastian Beyer, Yuri Bocchini, Alessandro Guareschi, Arseniy Goncharov, Kawa Mohemed, Volker Rudolph, Christian Sohns, Philipp Sommer   +17 more
wiley   +1 more source

Chagas Disease Cardiomyopathy: Immunopathology and Genetics

Mediators of Inflammation, 2014
Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), a particularly lethal ...
Edecio Cunha-Neto, Christophe Chevillard
doaj   +1 more source

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. [PDF]

PLoS ONE, 2013
BACKGROUND:Familial aggregation of Chagas cardiac disease in T. cruzi-infected persons suggests that human genetic variation may be an important determinant of disease progression.
Xutao Deng, Ester C Sabino, Edecio Cunha-Neto, Antonio L Ribeiro, Barbara Ianni, Charles Mady, Michael P Busch, Mark Seielstad, REDSII Chagas Study Group from the NHLBI Retrovirus Epidemiology Donor Study-II Component International   +8 more
doaj   +1 more source

A cardiac rehabilitation exercise program potentially inhibits progressive inflammation in patients with severe Chagas cardiomyopathy: A pilot single-arm clinical trial

Journal of Research in Medical Sciences, 2020
Background: Cardiac rehabilitation exerts anti-inflammatory effect on several cardiovascular diseases; however, these effects were not described for Chagas cardiomyopathy, which is associated with pro-inflammatory imbalance.
Luiz Fernando Rodrigues Junior, Fernanda de Souza Nogueira Sardinha Mendes, Vivian Liane Mattos Pinto, Paula Simplicio da Silva, Gilberto Marcelo Sperandio da Silva, Roberta Olmo Pinheiro, Andréa Silvestre de Sousa, Mauro Felippe Felix Mediano   +7 more
doaj   +1 more source

Complicações neurológicas em transplantes cardíacos [PDF]

, 2002
OBJECTIVE: Neurologic complications are known as important cause of morbidity and mortality in orthotopic heart transplantation. Our aim was to identify the frequency and outcome of neurologic complications after heart transplantation in a prospective ...
Almeida, Dirceu Rodrigues de, Branco, João Nelson Rodrigues, Carvalho, Antonio Carlos, Castelo Filho, Adauto, Diniz, Rosiane Viana Zuza, Gabbai, Alberto Alain, Malheiros, Suzana Maria Fleury, Massaro, Ayrton R.   +7 more
core   +3 more sources

Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]

, 2019
The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core   +1 more source