Results 41 to 50 of about 235,727 (237)

Sustained monomorphic ventricular tachycardia as the presenting sign of Chagas’ cardiomyopathy in a low prevalence setting, diagnosis and management challenges. A case report

Therapeutic Advances in Infectious Disease, 2022
Approximately 300,000 people in the United States are estimated to have Chagas’ disease, with cardiac manifestations including arrhythmias occurring in 20%–30% of patients.
Devang R. Amin, Sean Behan, Michelle Pengshung, Amber Khanna, Wendy S. Tzou, Nicholas Mantini, Andrés F. Henao-Martinez, Alexis Tumolo, Daniel W. Groves   +8 more
doaj   +1 more source

Trypanosoma cruzi-specific CD8+ T cells and other immunological hallmarks in chronic Chagas cardiomyopathy: Two decades of research

Frontiers in Cellular and Infection Microbiology, 2023
Trypanosoma cruzi, the causal agent of Chagas disease, has coexisted with humans for thousands of years. Therefore, the parasite has developed several mechanisms of antigenic variability that has allowed it to live inside the cells and evade the host ...
C. Puerta, A. Cuéllar, Paola Lasso, J. Mateus, John M. González   +4 more
semanticscholar   +1 more source

Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: Myocardium damage during Chagas' disease results from the immunological imbalance between pro- and production of anti-inflammatory cytokines and has been explained based on the Th1-Th2 dichotomy and regulatory T cell activity.
Paulo Marcos Matta Guedes, Fredy Roberto Salazar Gutierrez, Grace Kelly Silva, Renata Dellalibera-Joviliano, Gerson Jhonatan Rodrigues, Lusiane Maria Bendhack, Anis Rassi, Anis Rassi, André Schmidt, Benedito Carlos Maciel, José Antonio Marin Neto, João Santana Silva   +11 more
doaj   +1 more source

Heart rate variability as a biomarker in patients with Chronic Chagas Cardiomyopathy with or without concomitant digestive involvement and its relationship with the Rassi score

BioMedical Engineering OnLine, 2022
Dysautonomia plays an ancillary role in the pathogenesis of Chronic Chagas Cardiomyopathy (CCC), but is the key factor causing digestive organic involvement. We investigated the ability of heart rate variability (HRV) for death risk stratification in CCC
L. E. Silva, H. Moreira, Marina Madureira de Oliveira, L. S. S. Cintra, H. Salgado, R. Fazan, R. Tinós, A. Rassi, A. Schmidt, J. Marin-Neto   +9 more
semanticscholar   +1 more source

Two-dimensional strain derived parameters provide independent predictors of progression to Chagas cardiomyopathy and mortality in patients with Chagas disease

International Journal of Cardiology: Heart & Vasculature, 2022
Background Patients with chronic Chagas disease (CD) cardiomyopathy have a high mortality. We evaluated if two-dimensional (2D) strain (ε) parameters provide independent predictors of progression to CD cardiomyopathy and all-cause mortality.
R. Saraiva, M. Mediano, M. Quintana, G. M. Sperandio da Silva, A. R. Costa, A. Sousa, L. H. Sangenis, F. Mendes, H. H. Veloso, S. Xavier, M. T. Holanda, A. Hasslocher-Moreno   +11 more
semanticscholar   +1 more source

Treatment of Chagas Cardiomyopathy [PDF]

BioMed Research International, 2013
Chagas' disease (ChD), caused by the protozoaTrypanosoma cruzi(T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still brings much misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in ...
Botoni, Fernando A., Ribeiro, Antonio Luiz P., Marinho, Carolina Coimbra, Lima, Marcia Maria Oliveira, Nunes, Maria do Carmo Pereira, Rocha, Manoel Otávio C.   +5 more
openaire   +3 more sources

Multi-therapeutic strategy targeting parasite and inflammation-related alterations to improve prognosis of chronic Chagas cardiomyopathy: a hypothesis-based approach*

Memórias do Instituto Oswaldo Cruz, 2022
Chagas disease (CD), caused by infection by the protozoan parasite Trypanosoma cruzi, presents as main clinical manifestation the chronic chagasic cardiomyopathy (CCC).
J. Lannes-Vieira
semanticscholar   +1 more source

Mortality risk score for patients with Chagas cardiomyopathy and pacemaker. [PDF]

PLoS Negl Trop Dis
de Lima Peixoto G, de Siqueira SF, Nishioka SAD, Pedrosa AAA, Teixeira RA, Costa R, Martinelli Filho M.   +6 more
europepmc   +3 more sources

Metabolomic Profiling of End-Stage Heart Failure Secondary to Chronic Chagas Cardiomyopathy

International Journal of Molecular Sciences, 2022
Chronic Chagas cardiomyopathy (CCC) is the most frequent and severe clinical form of chronic Chagas disease, representing one of the leading causes of morbidity and mortality in Latin America, and a growing global public health problem.
M. Díaz, K. Burgess, R. Burchmore, M. Gómez, S. Gómez-Ochoa, L. E. Echeverría, Carlos Morillo, C. I. González   +7 more
semanticscholar   +1 more source

Rapidly Progressing Chagas Cardiomyopathy [PDF]

The American Society of Tropical Medicine and Hygiene, 2016
Chagas disease, caused by the parasite Trypanosoma cruzi, can cause a potentially life-threatening cardiomyopathy in approximately 10–40% of afflicted individuals. The decline in cardiac function characteristically progresses over the course of many years.
Hollowed, John, McCullough, Matthew, Sanchez, Daniel, Traina, Mahmoud, Hernandez, Salvador, Murillo, Efrain   +5 more
openaire   +5 more sources