Results 51 to 60 of about 235,727 (237)

Stroke correlates in chagasic and non-chagasic cardiomyopathies. [PDF]

PLoS ONE, 2012
BACKGROUND: Aging and migration have brought changes to the epidemiology and stroke has been shown to be independently associated with Chagas disease.
José Alberto Martins da Matta, Roque Aras, Cristiano Ricardo Bastos de Macedo, Cristiano Gonçalves da Cruz, Eduardo Martins Netto   +4 more
doaj   +1 more source

Modulation of Regulatory T Cells Activity by Distinct CD80 and CD86 Interactions With CD28/CTLA-4 in Chagas Cardiomyopathy

Frontiers in Cardiovascular Medicine, 2022
Chagas cardiomyopathy is the symptomatic cardiac clinical form (CARD) of the chronic phase of Chagas disease caused by Trypanosoma cruzi infection. It was described as the most fibrosing cardiomyopathies, affecting approximately 30% of patients during ...
Bruna F. Pinto, N. I. Medeiros, A. Teixeira-Carvalho, J. A. Fiúza, S. Elói-Santos, M. C. Nunes, S. A. Silva, Tereza C. M. Fontes-Cal, Mayara Belchior-Bezerra, W. Dutra, R. Corrêa-Oliveira, J. A. Gomes   +11 more
semanticscholar   +1 more source

Chagas Cardiomyopathy: From Romaña Sign to Heart Failure and Sudden Cardiac Death

Pathogens, 2021
Despite nearly a century of research and accounting for the highest disease burden of any parasitic disease in the Western Hemisphere, Chagas disease (CD) is still a challenging diagnosis, primarily due to its poor recognition outside of Latin America ...
A. Pino-Marín, G. Medina-Rincón, S. Gallo-Bernal, Alejandro Duran-Crane, Álvaro Ignacio Arango Duque, M. J. Rodríguez, R. Medina-Mur, F. Manrique, J. Forero, H. Medina   +9 more
semanticscholar   +1 more source

Mitochondrial DNA Haplogroups and Variants Predispose to Chagas Disease Cardiomyopathy

Hearts, 2023
Cardiomyopathies are major causes of heart failure. Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central and South America.
Frédéric Gallardo, Pauline Brochet, David Goudenège, João Paulo Silva Nunes, Pauline Andrieux, Barbara Maria Ianni, Amanda Farage Frade, Charles Mady, Ronaldo Honorato Barros Santos, Andreia Kuramoto, Samuel Steffen, Antonio Noedir Stolf, Pablo Pomerantzeff, Alfredo Inacio Fiorelli, Edimar Alcides Bocchi, Cristina Wide Pissetti, Bruno Saba, Fabrício C. Dias, Marcelo Ferraz Sampaio, Fabio Antônio Gaiotto, José Antonio Marin-Neto, Abílio Fragata, Ricardo Costa Fernandes Zaniratto, Sergio Siqueira, Giselle De Lima Peixoto, Fernando Bacal, Paula Buck, Rafael Ribeiro Almeida, Hui Tzu Lin-Wang, André Schmidt, Mario Hiroyuki Hirata, Eduardo Antonio Donadi, Alexandre Costa Pereira, Virmondes Rodrigues Junior, Martino Martinelli, Michel Naslavsky, Jorge Kalil, Vincent Procaccio, Edecio Cunha-Neto, Christophe Chevillard   +39 more
doaj   +1 more source

A genome-wide association study identifies novel susceptibility loci in chronic Chagas cardiomyopathy.

Clinical Infectious Diseases, 2021
BACKGROUND Chagas disease is an infectious disease caused by the parasite Trypanosoma cruzi and is endemic from Latin American countries. The goal of our study was to identify novel genetic loci associated with chronic Chagas cardiomyopathy development ...
Desiré Casares-Marfil, M. Strauss, P. Bosch-Nicolau, M. L. Lo Presti, I. Molina, C. Chevillard, E. Cunha-Neto, E. Sabino, A. Ribeiro, C. I. González, Javier Martín, M. Acosta-Herrera   +11 more
semanticscholar   +1 more source

Increased plasma levels of tumor necrosis factor-alpha in asymptomatic/"indeterminate" and Chagas disease cardiomyopathy patients [PDF]

Memorias do Instituto Oswaldo Cruz, 2003
We compared plasma tumor necrosis factor-alpha (TNF-alpha) levels among asymptomatic/"indeterminate" Chagas disease patients (ASY) and patients across the clinical spectrum of chronic Chagas disease cardiomyopathy (CCC). Idiopathic dilated cardiomyopathy
Renata Cristina Ferreira, Barbara M Ianni, Lucia CJ Abel, Paula Buck, Charles Mady, Jorge Kalil, Edecio Cunha-Neto   +6 more
doaj   +1 more source

Cardiovascular biomarkers as predictors of adverse outcomes in chronic Chagas cardiomyopathy

PLoS ONE, 2021
Background Chronic Chagas Cardiomyopathy (CCM) is a unique form of cardiomyopathy compared to other etiologies of heart failure. In CCM, risk prediction based on biomarkers has not been well-studied.
L. E. Echeverría, L. Z. Rojas, S. A. Gómez-Ochoa, O. Rueda-Ochoa, Cristian David Sosa-Vesga, T. Muka, J. Januzzi, R. Marcus, C. Morillo   +8 more
semanticscholar   +1 more source

Evaluation of the six-minute walk test in patients with chronic heart failure associated with Chagas' disease and systemic arterial hypertension Avaliação do teste de caminhada de seis minutos em pacientes com insuficiência cardíaca crônica associada à doença de Chagas e hipertensão arterial sistêmica

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: To evaluate physical capacity as determined by the six-minute walk test (6MWT) in patients with chronic heart failure due to Chagas' disease associated with systemic arterial hypertension (Chagas-SAH).
Kelly Cristina Colaço Dourado, Reinaldo Bulgarelli Bestetti, Augusto Cardinalli-Neto, José Antônio Cordeiro   +3 more
doaj   +1 more source

CD14 genotype and functional dichotomy of CD14+ and CD14- cells are associated with activated immune response and development of Chagas dilated cardiomyopathy [PDF]

Memorias do Instituto Oswaldo Cruz
We aimed to investigate the association of CD14 -260C/T (rs2569190) polymorphism and Chagas cardiomyopathy and the functional characteristics of CD14+ and CD14- monocytes upon infection with Trypanosoma cruzi.
Germano Carneiro Costa, Manoel Otávio da Costa Rocha, Paulo Eduardo Alencar de Souza, Diego Felipe SA Melo, Paula Rocha Moreira, Kenneth John Gollob, Maria do Carmo Pereira Nunes, Walderez Ornelas Dutra   +7 more
doaj   +2 more sources

Comprehensive analysis of three TYK2 gene variants in the susceptibility to Chagas disease infection and cardiomyopathy.

PLoS ONE, 2018
Tyrosine kinase 2 (TYK2) is a member of the Janus kinases family implicated in the signal transduction of type I interferons and several interleukins. It has been described that genetic mutations within TYK2 lead to multiple deleterious effects in the ...
Daniel A Leon Rodriguez, Marialbert Acosta-Herrera, F David Carmona, Nuria Dolade, Sofia Vargas, Luis Eduardo Echeverría, Clara Isabel González, Javier Martin   +7 more
doaj   +1 more source