Results 61 to 70 of about 13,067 (212)

Emerging and under-recognized Chagas cardiomyopathy in non-endemic countries [PDF]

open access: yes, 2012
Due to recent population emigration movements, an epidemic of Chagas disease is currently menacing most developed countries. The authors report the case of a 53-year-old Brazilian woman living in Europe for the last 10 years who developed heart failure ...
Cortez, J   +7 more
core   +1 more source

Bufalin‐Induced Epithelial‐to‐Mesenchymal Transition in Kidney Epithelial Cells

open access: yesCell Biology International, Volume 49, Issue 12, Page 1764-1786, December 2025.
ABSTRACT The kidney plays a central role in fluid, electrolyte, and blood pressure regulation, processes tightly coupled to Na⁺/K⁺‐ATPase activity. Beyond its canonical transport function, Na⁺/K⁺‐ATPase also acts as a signaling receptor for cardiotonic steroids (CTSs) such as bufalin, which have been implicated in fibrosis and epithelial‐to‐mesenchymal
Gabriela Morais de Oliveira Barros   +3 more
wiley   +1 more source

Deriving a parsimonious cardiac endpoint for use in epidemiological studies of Chagas disease: results from the Retrovirus Epidemiology Donor Study-II (REDS-II) cohort

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2021
Chagas cardiomyopathy (ChCM) is a severe consequence of Trypanosoma cruzi infection and has a range of electrocardiographic (ECG) and echocardiographic (ECHO) manifestations. There is a need for a standard and parsimonious research cardiac end point that
Lewis F. Buss   +6 more
doaj   +1 more source

Evaluation of VDR gene polymorphisms in Trypanosoma cruzi infection and chronic Chagasic cardiomyopathy [PDF]

open access: yes, 2016
Vitamin D is an important modulator of the immune response. It acts over several immune cell types where the Vitamin D receptor (VDR) is expressed.
Carmona, F.D.   +3 more
core   +2 more sources

Minimally Invasive Repair of Left Ventricular Aneurysm After Esophagectomy With Retrosternal Gastric Conduit: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
Preoperative CT and 3D reconstruction demonstrating an inferior left ventricular aneurysm in a patient with a retrosternal gastric conduit, highlighting the rationale for choosing a left mini‐thoracotomy approach. ABSTRACT In patients with prior esophagectomy and retrosternal gastric conduit, conventional sternotomy may be hazardous.
Junya Kitaura   +2 more
wiley   +1 more source

Ex vivo T-lymphocyte chemokine receptor phenotypes in patients with chronic Chagas disease

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Elucidating the molecules involved in the inflammatory process of chronic Chagas disease may allow identification of treatment targets.
Matheus Barbosa de Miranda   +5 more
doaj   +1 more source

Chagas disease cardiomyopathy: current concepts of an old disease Cardiomiopatia chagásica: conceitos atuais de doença antiga

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2008
Chagas disease continues to be a significant public health problem, as ca. 10 million people are still infected with T. cruzi in Latin America. Decades after primary infection, 30% of individuals can develop a form of chronic inflammatory cardiomyopathy ...
Angelina M.B. Bilate, Edecio Cunha-Neto
doaj   +1 more source

The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America [PDF]

open access: yes, 2018
It is estimated that between 8000 and 15 000 Trypanosoma cruzi infected babies are born every year to infected mothers in Chagas disease endemic countries. Currently, poor access to and performance of the current diagnostic algorithm, based on microscopy
Cruz, Israel   +7 more
core   +1 more source

A Novel Predictive Score to Identify the Necessity for Epicardial Ventricular Tachycardia Ablation: EPI‐VT‐Score

open access: yesJournal of Cardiovascular Electrophysiology, Volume 36, Issue 11, Page 2870-2877, November 2025.
The novel EPI‐VT‐Score accurately predicts the need for epicardial VT ablation using simple clinical, echocardiographic and ECG variables, optimizing patient selection and procedural outcomes. ABSTRACT Background Epicardial ventricular tachycardia (VT) ablation is a therapeutic option for drug‐refractory VT, particularly when endocardial ablation fails
Moneeb Khalaph   +17 more
wiley   +1 more source

Enhancing patient care: a multimodality strategy for dilated cardiomyopathy in Chagas disease [PDF]

open access: yesExploration of Cardiology
Chagas disease is a systemic illness characterized by acute and chronic phases. If untreated, it can lead to dysfunction of vital organs, notably the heart, ultimately resulting in heart failure.
Luigy Vasquez-Yeng   +8 more
doaj   +1 more source

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