Results 71 to 80 of about 12,753 (211)
Enhancing patient care: a multimodality strategy for dilated cardiomyopathy in Chagas disease [PDF]
Exploration of CardiologyChagas disease is a systemic illness characterized by acute and chronic phases. If untreated, it can lead to dysfunction of vital organs, notably the heart, ultimately resulting in heart failure.
Luigy Vasquez-Yeng +8 more
doaj +1 more source
Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy. [PDF]
, 2016 Host and parasite diversity are suspected to be key factors in Chagas disease pathogenesis. Experimental investigation of underlying mechanisms is hampered by a lack of tools to detect scarce, pleiotropic infection foci.
Francisco, Amanda Fortes +4 more
core +1 more source
Pregnancy, Volume 1, Issue 4, July 2025.Abstract Introduction Over 300,000 people living in the United States are estimated to have Chagas disease, a condition for which mother to child transmission may occur and early diagnosis is essential to reduce Chagas‐related morbidity and mortality. This study evaluated positive Trypanosoma cruzi (T. cruzi) screening serology among maternal donors of
Naseem Alavian +6 more
wiley +1 more source
Putting Infection Dynamics at the Heart of Chagas Disease. [PDF]
, 2016 In chronic Trypanosoma cruzi infections, parasite burden is controlled by effective, but nonsterilising immune responses. Infected cells are difficult to detect because they are scarce and focally distributed in multiple sites.
Kelly, John M, Lewis, Michael D
core +1 more source
G protein‐coupled receptor‐mediated autophagy in health and disease
British Journal of Pharmacology, Volume 182, Issue 14, Page 3151-3162, July 2025.G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan +2 more
wiley +1 more source
The effect of beta-blockade on myocardial remodelling in Chagas' cardiomyopathy
Clinics, 2012 OBJECTIVE: Chagas' disease has spread throughout Latin America because of the high rate of migration among these countries. Approximately 30% of Chagas' patients will develop cardiomyopathy, and 10% of these will develop severe cardiac damage leading to ...
Walace de Souza Pimentel +8 more
doaj +1 more source
Clinical Presentations of Chagas Cardiomyopathy
Case Reports in Cardiology, 2020 Chronic Chagas cardiomyopathy (CCC) is the most common cause of nonischemic cardiomyopathy in endemic Latin American countries. Immigrants to the United States suffer from this disease, but it is underrecognized.
Malik Shehadeh, Ana Barac, Rachel Marcus
doaj +1 more source
Tropical Medicine &International Health, Volume 30, Issue 7, Page 673-684, July 2025.Abstract Objectives To determine, in a randomised placebo‐controlled trial, if cutaneous adverse reactions during treatment (CARDT) with Benznidazole occur as often as with Nifurtimox, and whether the dose and duration of treatment change that frequency.
Juan Carlos Villar +7 more
wiley +1 more source
Venous endothelial dysfunction in Chagas' disease patients without heart failure [PDF]
, 2006 OBJECTIVE: To analyze the venous endothelial function in Chagas' disease patients without heart failure. METHODS: The Chagas' disease Group (G1) was composed by 14 women and 2 men aged 46 ± 2,7 and the Control Group (G0) by 7 women and 1 man matched by ...
Casarini, Dulce Elena +9 more
core +4 more sources
ESC Heart Failure, Volume 12, Issue 3, Page 2190-2199, June 2025.In this retrospective, observational study of a real‐life cohort of patients with heart failure with reduced ejection fraction, long‐term survival was improved in patients who achieved sustained reverse remodeling. Greater increases in ejection fraction (EF) and reductions in left ventricular end‐systolic diameter at the time of EF recovery, greater ...
Silas Ramos Furquim +13 more
wiley +1 more source