Results 51 to 60 of about 22,058 (147)
Simple chalcones and bis-chalcones ethers as possible pleiotropic agents
Journal of Enzyme Inhibition and Medicinal Chemistry, 2015 The synthesis, the antioxidative properties and the lipoxygenase (LOX) and acetylcholinesterase (AChE) inhibition of a number of 4-hydroxy-chalcones diversely substituted as well as of a series of bis-chalcones ether derivatives are reported. The chalcones derivatives were readily produced using a Claisen-Schmidt condensation in a ultra sound bath in ...
Liargkova, T. +4 more
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MethodsXIn this study, a straightforward spectrophotometric method was developed for quantifying the total content of chalcones in a sample. The method exhibits linearity, accuracy, precision, repeatability, and enables the estimation of total chalcone content ...
J.R.S. Botelho +4 more
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Antiproliferative Effect of Acridine Chalcone Is Mediated by Induction of Oxidative Stress
Biomolecules, 2020 Chalcones are naturally occurring phytochemicals with diverse biological activities including antioxidant, antiproliferative, and anticancer effects. Some studies indicate that the antiproliferative effect of chalcones may be associated with their pro ...
Peter Takac +6 more
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Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin
Frontiers in Microbiology, 2017 Staphylococcus aureus (S.aureus) resistance, considered a dilemma for the clinical treatment of this bacterial infection, is becoming increasingly intractable.
Bing Zhang +9 more
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4-({4-[(2E)-3-(2,5-Dimethoxyphenyl)prop-2-enoyl]phenyl}amino)-4-oxobutanoic Acid
Molbank, 2017 A dimethoxy amide chalcone has been synthesized in a two-step reaction. First, an amine chalcone was synthesized by the reaction of 4′-aminoacetophenone and 2,5-dimethoxybenzaldehyde using 40% NaOH solution as a catalyst in ethanol, and then followed by ...
Hery Suwito +4 more
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Evaluation of direct pulp capping with a synthetic chalcone: a preliminary histological study.
Journal of Oral Research, 2015 The aim of this study is to evaluate the action of the synthetic chalcone 1-phenyl-3-(4-chlorophenyl)-2-propen-1-one to induce pulp healing in rats.
David Tames +6 more
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Synthesis and Identification of Phenyl Azochalcone & bis- azo – Chalcone Derivatives Derived from P-amino Acetophenone [PDF]
Kirkuk Journal of Science, 2018 This work involves the synthesis of different substituted amino-chalcones via claisen- schmidt condensation reaction between p-amino acetophenone and different aromatic substituted benzaldehydes. The second step involves the conversion of amino-chalcones
Zahraa Talib Ghlib +2 more
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Pharmacology & Pharmacy, 2011 A new series of chalcones (4a-c) and allylicchalcones (11a-b) have been prepared by the Claisen-Schmidt condensation. A novel series of pyrazolicchalcones (5a-c) have been synthesized by the reaction of respective chalcones (4a-c) and hydrazine hydrate.
Tan Nhut Doan, Dao Thanh Tran
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, 2021 The human skin is pivotal for protecting the body from various stresses and diseases, regulating several physiological aspects, and sensing any signal changes around the environment. To work and function optimally, the skin should be protected and cared regularly by using some treatments.
Jumina,, +2 more
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PharmaceuticalsBackground: In this study, two chalcone analogs were synthesized through in silico and experimental methods, and their potential to inhibit the lipoxygenase enzyme, which plays a role in the inflammation pathway, was assessed. Specifically, this study is
Nikitas Georgiou +9 more
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