Results 51 to 60 of about 74,636 (287)

Phthalocyanine-chalcone conjugates

open access: yesJournal of Porphyrins and Phthalocyanines, 2016
A phthalocyanine-chalcone conjugate was previously reported to retain the full photodynamic activity of the phthalocyanine and a slightly lowered antivascular effect of the chalcone. Assuming that it was due to an insufficient release of the chalcone, we described here several grafting modes applied to the preparation of phthalocyanine-chalcone ...
Khalil Bennis   +22 more
openaire   +4 more sources

Anti-cancer effect of naringenin chalcone is mediated via the induction of autophagy, apoptosis and activation of PI3K/Akt signalling pathway

open access: yesBangladesh Journal of Pharmacology, 2016
The aim of the current study was to investigate the in vitro and in vivo anti-tumor effects of naringenin chalcone in U87MG human glioblastoma cells and in xenograft mice model.
Shuai Zhang   +4 more
doaj   +1 more source

Comparative Molecular Mechanisms of Biosynthesis of Naringenin and Related Chalcones in Actinobacteria and Plants: Relevance for the Obtention of Potent Bioactive Metabolites

open access: yesAntibiotics, 2022
Naringenin and its glycosylated derivative naringin are flavonoids that are synthesized by the phenylpropanoid pathway in plants. We found that naringenin is also formed by the actinobacterium Streptomyces clavuligerus, a well-known microorganism used to
Juan F. Martín, Paloma Liras
doaj   +1 more source

Evaluation of the Anti-Inflammatory Effect of Chalcone and Chalcone Analogues in a Zebrafish Model [PDF]

open access: yesMolecules, 2013
The aim of this study was to investigate novel chalcones with potent anti-inflammatory activities in vivo. Chalcone and two chalcone analogues (compound 5 and 9) were evaluated using a caudal fin-wounded transgenic zebrafish line “Tg(mpx:gfp)” to visualize the effect of neutrophil recruitment dynamically.
Yau-Hung Chen   +5 more
openaire   +3 more sources

LAP3, a novel plant protein required for pollen development, is essential for proper exine formation [PDF]

open access: yes, 2009
We isolated lap3-1 and lap3-2 mutants in ascreen for pollen that displays abnormal stigma binding.Unlike wild-type pollen, lap3-1 and lap3-2 pollen exine isthinner, weaker, and is missing some connections betweentheir roof-like tectum structures.
Carlson, Ann L   +7 more
core   +2 more sources

Toxicity Assessments of Chalcone and Some Synthetic Chalcone Analogues in a Zebrafish Model [PDF]

open access: yesMolecules, 2014
The aim of this study was to investigate the in vivo toxicities of some novel synthetic chalcones. Chalcone and four chalcone analogues 1a–d were evaluated using zebrafish embryos following antibody staining to visualize their morphological changes and muscle fiber alignment.
Ching Yuh Chern   +6 more
openaire   +3 more sources

Ethanol triggers grape gene expression leading to anthocyanin accumulation during berry ripening [PDF]

open access: yes, 2002
Recent studies have shown that low doses of ethanol stimulate the maturation of some fruits. The present work showed that spraying Cabernet Sauvignon grapes, with 5% ethanol at veraison enhances the anthocyanin accumulation.
Chervin, Christian   +9 more
core   +2 more sources

Molecular targets and anticancer activity of quinoline–chalcone hybrids: literature review

open access: yesRSC Advances, 2020
α,β-Unsaturated chalcone moieties and quinoline scaffolds play an important role in medicinal chemistry, especially in the identification and development of potential anticancer agents.
M. Mohamed, G. Abuo‐Rahma
semanticscholar   +1 more source

Green Synthesis of Chalcone Derivatives Using Chalcones as Precursor

open access: yes, 2022
Recently, the use of green methodologies like sonication, use of ionic liquids, etc. attracted the attention of researchers in the field of organic synthesis as they have advantages such as mild reaction conditions, environmentally benign procedures, etc.
Surbhi, Dhadda,   +2 more
openaire   +2 more sources

Steroidal chalcones and derivatives: a review

open access: yesArkivoc, 2021
It was observed that the presence of heterocycles to steroids often leads to a change in their physiological activity and the appearance of new interesting biological precursors. Recent developments in the syntheses of steroidal chalcones and their derivatives are described herein. The biological activities of those steroidal derivatives for which data
Ibrahim-Ouali, Malika, Dumur, Frédéric
openaire   +3 more sources

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