Results 51 to 60 of about 33,379 (241)

Electron Donor–Acceptor Complexes Without Preinstalled Sacrificial Leaving Groups: Applications in Synthesis

open access: yesHelvetica Chimica Acta, EarlyView.
Leaving‐group–free electron donor–acceptor (EDA) complexes have emerged as a practical platform for photocatalyst‐free radical generation under visible light. This review highlights recent advances in coupling and cyclization reactions driven by such EDA complexes, emphasizing their atom‐economical and sustainable feature.
Wenheng Liu, Line Næsborg
wiley   +1 more source

Bioaccessibility of anthocyanins and bioactive compounds from Brazilian berries and their food matrix interaction: an in vitro gastrointestinal digestion study coupled to UHPLC‐ESI‐TQD‐MS/MS analysis

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Several commercial berries have been examined for anthocyanin composition, bioaccessibility, and bioactive effects, while Brazilian berries remain underexplored. This study aimed to access the effect of in vitro gastrointestinal digestion on anthocyanin bioaccessibility, stability, and antioxidant potential in black pitanga (Eugenia
Paulo Berni   +6 more
wiley   +1 more source

Microwave‐Assisted Organic Syntheses in Deep Eutectic Solvents: A Win‐Win Association for Sustainable Chemistry

open access: yesChemistryOpen, EarlyView.
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye   +2 more
wiley   +1 more source

Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin

open access: yesFrontiers in Microbiology, 2017
Staphylococcus aureus (S.aureus) resistance, considered a dilemma for the clinical treatment of this bacterial infection, is becoming increasingly intractable.
Bing Zhang   +9 more
doaj   +1 more source

Synthesis of Pyrido[2,3‐d]Azolopyrimidinones: Design and Epidermal Growth Factor Receptor‐Targeted Molecular Docking Toward Novel Anticancer Leads

open access: yesChemistryOpen, EarlyView.
New pyrido[2,3‐d]azolopyrimidinones were synthesized and evaluated as potent EGFR‐targeted anticancer leads. Molecular docking and cytotoxicity studies revealed strong receptor binding and submicromolar activity, highlighting this scaffold as a promising framework for future targeted drug development.
Sobhi M. Gomha   +6 more
wiley   +1 more source

University teaching of mass spectrometry as a key practical technique within the context of a fully integrated, spiral curriculum

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
Rationale Mass spectrometry (MS) is introduced to high school students in the UK in many pre‐university course syllabi. As such, we have identified the use of MS as a key technique that should be taught practically to undergraduates from the outset of their studies.
Andrew F. Worrall   +3 more
wiley   +1 more source

4-({4-[(2E)-3-(2,5-Dimethoxyphenyl)prop-2-enoyl]phenyl}amino)-4-oxobutanoic Acid

open access: yesMolbank, 2017
A dimethoxy amide chalcone has been synthesized in a two-step reaction. First, an amine chalcone was synthesized by the reaction of 4′-aminoacetophenone and 2,5-dimethoxybenzaldehyde using 40% NaOH solution as a catalyst in ethanol, and then followed by ...
Hery Suwito   +4 more
doaj   +1 more source

Rapid Structural Analysis of Natural Products Using MicroED

open access: yesSmall, EarlyView.
The cryoEM method, MicroED used for rapid analysis and structure determination of natural products that remained unattainable by other structural biology methods ABSTRACT Structural analysis of natural products remains challenging due to their inherent complexity and limited availability.
Jieye Lin   +3 more
wiley   +1 more source

Evaluation of direct pulp capping with a synthetic chalcone: a preliminary histological study.

open access: yesJournal of Oral Research, 2015
The aim of this study is to evaluate the action of the synthetic chalcone 1-phenyl-3-(4-chlorophenyl)-2-propen-1-one to induce pulp healing in rats.
David Tames   +6 more
doaj   +1 more source

Synthesis and Identification of Phenyl Azochalcone & bis- azo – Chalcone Derivatives Derived from P-amino Acetophenone [PDF]

open access: yesKirkuk Journal of Science, 2018
This work involves the synthesis of different substituted amino-chalcones via claisen- schmidt condensation reaction between p-amino acetophenone and different aromatic substituted benzaldehydes. The second step involves the conversion of amino-chalcones
Zahraa Talib Ghlib   +2 more
doaj   +1 more source

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