Results 91 to 100 of about 36,394 (277)

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

open access: yesCell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu   +5 more
wiley   +1 more source

Secondary metabolite profiling of the model legume Lotus japonicus during its symbiotic interaction with Mesorhizobium loti [PDF]

open access: yes, 2014
Plant secondary metabolites, particularly flavonoids, are key components in the early stages of nitrogen-fixing symbiosis. Despite their importance, the endogenous secondary metabolites involved in symbiosis have not yet been identified in the model ...
Bartholomew, B.   +5 more
core   +1 more source

Aggregation-Induced Emission Properties of Triphenylamine Chalcone Compounds [PDF]

open access: green, 2021
Yingpeng Zhang   +4 more
openalex   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

open access: yesThe FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova   +5 more
wiley   +1 more source

Synthesis and Characterisation of Multi-Ferrocenyl Compounds Containing Enone Moieties [PDF]

open access: yes, 2015
Ferrocene based organometallic compounds have received intense attention in synthetic chemistry due to their increasing interest in biological, optical, and electrochemical properties.
Pandey, Annu Kumari
core  

Light regulates tomato fruit metabolome via SlDML2‐mediated global DNA demethylation

open access: yesJournal of Integrative Plant Biology, EarlyView.
In tomato growth and development, red and blue light signals are captured by the photoreceptors phyB2 and CRY1a, which kickstart tomato fruit ripening by activating HY5, which activates DNA demethylation via DML2 to trigger a metabolic and ripening transformation cascade within the tomato.
Zixin Zhang   +15 more
wiley   +1 more source

Chalcone-based Selective Inhibitors of a C4 Plant Key Enzyme as Novel Potential Herbicides [PDF]

open access: yes, 2016
Weeds are a challenge for global food production due to their rapidly evolving resistance against herbicides. We have identified chalcones as selective inhibitors of phosphoenolpyruvate carboxylase (PEPC), a key enzyme for carbon fixation and biomass ...
Bott, M.   +7 more
core   +2 more sources

Recent Updates on Synthetic Strategies of Chalcone Scaffold and their Heterocyclic Derivatives [PDF]

open access: diamond, 2023
Mohamed A. Amin   +4 more
openalex   +1 more source

Chalcones in Dermatology

open access: yes, 2021
The human skin is pivotal for protecting the body from various stresses and diseases, regulating several physiological aspects, and sensing any signal changes around the environment. To work and function optimally, the skin should be protected and cared regularly by using some treatments.
Jumina,,   +2 more
openaire   +3 more sources

Metabolo‐Transcriptomics Analyses Reveal Alfalfa Adaptation to Combined Saline‐Alkali and Low‐Temperature Stress in the Field

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Alfalfa (Medicago sativa L.) is known as the ‘King of Forage’ because of its high protein content and excellent palatability. Alfalfa productivity is adversely affected in cold regions with saline‐alkali soils. However, the mechanisms underlying the response of alfalfa to combined saline‐alkali and low‐temperature stress under field conditions
Rui Guo   +8 more
wiley   +1 more source

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