Results 131 to 140 of about 15,473 (263)

A Review of Natural and Synthetic Chalcones as Anticancer Agents Targeting Topoisomerase Enzymes

open access: yesMolecules
Cancer remains one of the leading causes of morbidity and mortality worldwide, driving the search for innovative and selective therapeutic agents. Topoisomerases I and II are essential enzymes involved in key cellular processes such as DNA replication ...
François-Xavier Toublet   +2 more
doaj   +1 more source

Chalcones Enhance TRAIL-Induced Apoptosis in Prostate Cancer Cells

open access: yes, 2009
Chalcones exhibit chemopreventive and antitumor effects. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a naturally occurring anticancer agent that induces apoptosis in cancer cells and is not toxic to normal cells.
Lukasz Sedek   +6 more
core   +1 more source

Identification of Exhaled Volatile Organic Compounds Biomarkers for Lung Cancer Under Data‐Limited Conditions Using Data Augmentation and Multi‐View Feature Selection

open access: yesAdvanced Intelligent Discovery, Volume 2, Issue 3, June 2026.
This work introduces a novel framework for identifying non‐small cell lung cancer biomarkers from hundreds of volatile organic compounds in breath, analyzed via gas chromatography‐mass spectrometry. This method integrates generative data augmentation and multi‐view feature selection, providing a stable and accurate solution for biomarker discovery in ...
Guancheng Ren   +10 more
wiley   +1 more source

Water solubility structure activity relationship of chalcones for aqueous applications

open access: yes, 2023
Chalcones are a group of synthetic and naturally occurring small molecules containing two aromatic rings separated by an α,β-unsaturated carbonyl moiety.
Yocum, Grace
core  

An Overview of Anticancer Chalcones with Apoptosis Inducing Activity

open access: yesJournal of Mazandaran University of Medical Sciences, 2017
Cancer is a complex and life-threatening disease involving uncontrollable cell proliferation, evading apoptosis, and metastasis. Despite recent developments in cancer chemotherapy, there are no effective broad spectrum anticancer agents that could ...
Hassan Mirzaei   +2 more
doaj  

Chalcones and their analogues as potential drugs.

open access: yes, 2006
1 SUMMARY This dissertation thesis deals with searching for potential drugs, particularly with preparation and biological activity study of natural compounds derivatives - chalcones.
Chlupáčová, Marta
core  

Formation and Characterization of Insoluble Anthocyanins‐λ‐carrageenan Biopolyelectrolyte Complexes: Structural Morphology, Thermal Stability, and Release Dynamics

open access: yesChemFoodChem, Volume 2, Issue 2, June 2026.
Insoluble biopolyelectrolyte complexes formed between blackberry anthocyanins and λ‐carrageenan are investigated. Optimal complexation occurs at low carrageenan ratios and acidic pH, producing porous hydrogel‐like structures with enhanced thermal stability.
Tomás Garrido   +5 more
wiley   +1 more source

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

open access: yesFuture Postharvest and Food, Volume 3, Issue 2, Page 142-162, June 2026.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq   +2 more
wiley   +1 more source

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

open access: yesFuture Postharvest and Food, Volume 3, Issue 2, Page 163-184, June 2026.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja   +3 more
wiley   +1 more source

Water Solubility of Chalcones for Safer Aqueous Applications

open access: yes, 2022
Chalcones are a group of synthetic and naturally occurring small molecules containing two aromatic rings separated by an α,β-unsaturated carbonyl moiety.
Yocum, Grace
core  

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