Results 51 to 60 of about 54,606 (348)

Synthesis of Chalcones with Anticancer Activities [PDF]

Molecules, 2012
Several chalcones were synthesized and their in vitro cytotoxicity against various human cell lines, including human breast adenocarcinoma cell line MCF-7, human lung adenocarcinoma cell line A549, human prostate cancer cell line PC3, human adenocarcinoma cell line HT-29 (colorectal cancer) and human normal liver cell line WRL-68 was evaluated. Most of
Suvitha Syam, Siddig Ibrahim Abdelwahab, Mohammed Ali Al-Mamary, Syam Mohan   +3 more
openaire   +4 more sources

Synthesis, spectral correlation and insect antifeedant activities of some 2-benzimidazole chalcones

Journal of Saudi Chemical Society, 2016
Some substituted styryl 2-benzimidazole ketones have been synthesised by fly-ash:H2SO4 catalysed aldol condensation of 2-benzimidazole methyl ketone and various substituted benzaldehydes in microwave oven. The yields of these chalcones are more than 70%.
P. Janaki, K.G. Sekar, G. Thirunarayanan
doaj   +1 more source

Reaction of Chalcones with Cellular Thiols. The Effect of the 4-Substitution of Chalcones and Protonation State of the Thiols on the Addition Process. Diastereoselective Thiol Addition

Molecules, 2021
Several biological effects of chalcones have been reported to be associated with their thiol reactivity. In vivo, the reactions can result in the formation of small-molecule or protein thiol adducts.
Fatemeh Kenari, Szilárd Molnár, Pál Perjési   +2 more
doaj   +1 more source

Reaction of chalcones with phenylhydrazine [PDF]

Pharmaceutical Chemistry Journal, 1976
AbstractChalkone (I) reagieren mit Phenylhydrazin (II) zu Pyrazolinen (III) (Ausbeute 38 ‐ 72%).
Yakovenko V.I., Oganesyan E.T., Zvolinskii V.P., Zakharov V.F.   +3 more
openaire   +4 more sources

Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenone

E-Journal of Chemistry, 2004
Eleven new chalcones have been sysnthesised by condensing 3-bromo-4-(p-tolyl sulphonamido) acetophenone with different aromatic aldehydes using the method or Rohrman et al. The antimicrobial activity of these chalcones has been tested by adopting “paper
Miss Rashmi Jain, O. P. Chourasia, J. Tirumala Rao   +2 more
doaj   +1 more source

Natural Chalcones in Chinese Materia Medica: Licorice

Evidence-Based Complementary and Alternative Medicine, 2020
Licorice is an important Chinese materia medica frequently used in clinical practice, which contains more than 20 triterpenoids and 300 flavonoids. Chalcone, one of the major classes of flavonoid, has a variety of biological activities and is widely ...
Danni Wang, Jing Liang, Jing Zhang, Yuefei Wang, X. Chai   +4 more
semanticscholar   +1 more source

Phthalocyanine-chalcone conjugates

Journal of Porphyrins and Phthalocyanines, 2016
A phthalocyanine-chalcone conjugate was previously reported to retain the full photodynamic activity of the phthalocyanine and a slightly lowered antivascular effect of the chalcone. Assuming that it was due to an insufficient release of the chalcone, we described here several grafting modes applied to the preparation of phthalocyanine-chalcone ...
Khalil Bennis, Khalil Bennis, Derya Topkaya, Derya Topkaya, Serkan Alpugan, Vefa Ahsen, Charlene Vey, Charlene Vey, Jérémie Fournier-dit-Chabert, Jérémie Fournier-dit-Chabert, Mélissa Cucca, Mélissa Cucca, Sinem Tuncel Kostakoğlu, Sebile Işık Büyükekşi, Gökçe Canan Taşkın, Florian Albrieux, Ayşe Gül Gürek, Devrim Atilla, Fallia Aribi, Fallia Aribi, Fabienne Dumoulin, Sylvie Ducki, Sylvie Ducki   +22 more
openaire   +4 more sources

Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles [PDF]

, 2019
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Carradori, Simone, Chimenti, Paola, Cirilli, Roberto, Guglielmi, Paolo, Petzer, Anél, Petzer, Jacobus P., Poli, Giulio, Rotondi, Giulia, Secci, Daniela   +8 more
core   +1 more source

Chalcones Isolated from Arrabidaea brachypoda Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of Staphylococcus aureus

Antibiotics, 2020
Bacterial resistance to antibiotics has become a public health issue around the world. The present study aimed to evaluate the antibacterial activity of chalcones isolated from flowers of Arrabidaea brachypoda, and their potential as efflux pump ...
Luis Mário Rezende-Júnior, Leila Maria de Sousa Andrade, A. Leal, Avilnete B.S. Mesquita, A. Santos, J. B. D. S. Neto, J. P. Siqueira-Júnior, C. Nogueira, G. Kaatz, H. Coutinho, N. Martins, C. D. da Rocha, H. M. Barreto   +12 more
semanticscholar   +1 more source

Green Synthesis of Chalcone Derivatives Using Chalcones as Precursor

, 2022
Recently, the use of green methodologies like sonication, use of ionic liquids, etc. attracted the attention of researchers in the field of organic synthesis as they have advantages such as mild reaction conditions, environmentally benign procedures, etc.
Surbhi, Dhadda,, Giri, Goswami, Prakash, Himanshu, Sharma,   +2 more
openaire   +2 more sources