Results 51 to 60 of about 10,225 (206)
ChemistryOpen, EarlyView.In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye +2 more
wiley +1 more source
ChemistryOpen, EarlyView.New pyrido[2,3‐d]azolopyrimidinones were synthesized and evaluated as potent EGFR‐targeted anticancer leads. Molecular docking and cytotoxicity studies revealed strong receptor binding and submicromolar activity, highlighting this scaffold as a promising framework for future targeted drug development.
Sobhi M. Gomha +6 more
wiley +1 more source
Synthesis and Characterization of Novel Heterocyclic Chalcones from 1-Phenyl-1H-pyrazol-3-ol
Molecules, 2022 An efficient synthetic route to construct diverse pyrazole-based chalcones from 1-phenyl-1H-pyrazol-3-ols bearing a formyl or acetyl group on the C4 position of pyrazole ring, employing a base-catalysed Claisen–Schmidt condensation reaction, is described.
Arminas Urbonavičius +9 more
doaj +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte +3 more
wiley +1 more source
Chalcones and Dihydrochalcones Augment TRAIL-Mediated Apoptosis in Prostate Cancer Cells
Molecules, 2010 Chalcones and dihydrochalcones exhibit chemopreventive and antitumor activity. TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) is a natural endogenous anticancer agent.
Wojciech Krol +4 more
doaj +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.Rationale Mass spectrometry (MS) is introduced to high school students in the UK in many pre‐university course syllabi. As such, we have identified the use of MS as a key technique that should be taught practically to undergraduates from the outset of their studies.
Andrew F. Worrall +3 more
wiley +1 more source
From 0D to 3D liquid crystal elastomers architectures: Fabrications and applications
Responsive Materials, EarlyView.This review presents a dimension‐oriented overview of liquid crystal elastomers (LCEs), highlighting their molecular alignment, fabrication strategies, and programmable deformations from 0D particles to 3D architectures. Emphasis is placed on how dimensionality guides design principles, enables diverse actuation modes, and bridges fundamental ...
Mingxuan Liu +8 more
wiley +1 more source
Synthesis and Biological Evaluation of Some New Chalcones Containing 2,5-Dimethylfuran Moiety
E-Journal of Chemistry, 2011 A series of new chalcones (3a-g) were prepared by Claisen-Schmidt condensation of 3-acetyl-2,5-dimethylfuran with various substituted aromatic aldehydes in presence of aqueous solution of potassium hydroxide and ethanol at room temperature.
S. Sridhar +2 more
doaj +1 more source
Molecules, 2020 Our previous work identified isoxazole-based chalcones and their dihydropyrazole derivatives as two important five-membered heterocycles having antitubercular activity.
Afzal Shaik +5 more
doaj +1 more source
Smart Molecules, EarlyView.This study develops a series of unimolecular photoinitiators, BP‐S1‐5, by incorporating hydrogen‐donating groups into a benzophenone framework. This method reduces the reliance on co‐initiators, and enables BP‐S1‐5 with efficient photoinitiation and excellent molding capability.
Yu Li +11 more
wiley +1 more source