Results 71 to 80 of about 2,639,548 (308)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Classifications of innovations: Survey and future directions [PDF]
The purpose of this paper is to focus on similarity and/or heterogeneity of taxonomies of innovation present in the economic fields to show as the economic literature uses different names to indicate the same type of technical change and innovation, and ...
Mario Coccia
core
Why Reinvent the Wheel? The Efficacy of the Systematic Problem Solving Method 'TRIZ' and it Value for Innovation in Engineering and Implications for Engineering Management [PDF]
, 2005 The engineering industry needs to be more innovative. A case study of a recent breakthrough innovative development by Michelin is discussed. The influence of prior training with systematic problem solving method TRIZ, on the innovation team, is assessed ...
Filmore, Paul R., Thomond, Peter N.
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Les défis posés par l’unité pédagogique pour élèves allophones arrivants (UPE2A) à la forme scolaire
Recherches en ÉducationPupils categorized by the educational institution as newly arrived allophone pupils have, under the consideration of special educational needs, compensatory rights materialized by linguistic and pedagogical support in a pedagogical unit for incoming ...
Isabelle Rigoni
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Reframing technical change: Livestock Fodder Scarcity Revisited as Innovation Capacity Scarcity: Part 2. A Framework for Analysis [PDF]
This is the second in a series of three papers that develop a conceptual framework for a project on livestock fodder innovation. The paper begins by reviewing the evolving paradigms of agricultural research and innovation over the last 30 years or so and
Bezkorowajnyj, Peter +2 more
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Climate change adaptation innovation in the water sector in Africa: Dataset. [PDF]
Data Brief, 2023 Nyiwul L.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Structural Change, Growth and Bazaar Effects in the Single EU Market [PDF]
This paper analyzes the link between structural change, growth and bazaar effects in the context of open economies. At first we consider the theoretical basis of structural change and discuss the interdependencies between trade, foreign direct investment
Dora Borbély, Paul J.J. Welfens
core