Results 91 to 100 of about 2,639,548 (308)

Triple-loop learning as foundation for profound change, individual cultivation, and radical innovation: Construction processes beyond scientific and rational knowledge. [PDF]

open access: yes
Purpose: How does new knowledge or profound change come about and which processes of construction are involved? This article aims at developing an epistemological as well as methodological framework which is capable of explaining how profound and radical
Peschl, Markus F.
core   +1 more source

Complementary Resources and the Exploitation of Technological Innovations [PDF]

open access: yes, 2003
Technological innovation often results when the resources of a small firm are combined with those of a large one. This is because small and large firms characteristically possess complementary resources whose combination can facilitate innovation success.
Covin, Jeffrey G.   +2 more
core   +1 more source

Service change and innovation in community end-of-life care during the COVID-19 pandemic: Qualitative analysis of a nationwide primary care survey. [PDF]

open access: yesPalliat Med, 2022
Mitchell S   +9 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Édito – Diversité des processus de traduction dans des champs de pratiques professionnelles et sociales

open access: yesRecherches en Éducation, 2020
Muriel Deltand   +3 more
doaj   +1 more source

Reframing technical change: Livestock Fodder Scarcity Revisited as Innovation Capacity Scarcity: Part 3. Tools for Diagnosis and Institutional Change in Innovation Systems [PDF]

open access: yes
The exploration of fodder innovation capacity requires tools to undertake the following tasks: (i) Diagnosis of fodder innovation capacity to identify project starting points, including micro and macro elements (ii) Socio-economic benchmarking, and ...
Bezkorowajnyj, Peter   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Merger Policy and Innovation: Must Enforcement Change to Account for Technological Change? [PDF]

open access: yes
Merger policy is the most active area of U.S. antitrust policy. It is now widely believed that merger policy must move beyond its traditional focus on static efficiency to account for innovation and address dynamic efficiency.
Howard A. Shelanski, Michael L. Katz
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Understanding the potential role of membership organisations in the sustainable spread of innovation [PDF]

open access: yes
Innovation must be defined as "change for the better" rather than as mere 'novelty' or "change for change's sake". Membership organisations have a key role to play in the cost effective spread of innovation.
Donovan, Kevin, Schmoller, Seb
core  

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