Results 111 to 120 of about 2,639,548 (308)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Recherches en ÉducationThis article focuses on the reasons for teachers commitment in two pedagogical devices prescribing forms co-teaching (the “More teachers than classes” and a co-teaching device in eleven one-class rural Ardèche in mountain schools).
Quentin Magogeat
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Quand un coenseignement interroge la forme scolaire au profit de l’éducation inclusive
Recherches en ÉducationThe objective of this study was to better understand in what and how the evolution of co-teaching over a school year between a primary school teacher and a physical education teacher transforms the traditional school form for the benefit of the inclusive
Maxime Tant
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Extending and Deepening the Analysis of Innovation Systems - with Empirical Illustrations from the DISCO-project [PDF]
Traditionally innovation system have been analysed either as rooted in the R&Dsystem or the production system. This paper suggests a broader approach to national innovation systems and analyse these as rooted in constellation of a national production ...
Bengt-Åke Lundvall +1 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Induced Innovations and Foreign Workers in U.S. Agriculture [PDF]
A cost function approach of induced innovation is used to measure the biases in U.S. agricultural technology between 1948-1994. The results show significant labor-saving, capital-using technical change. Focusing on the impact of migration policy on labor-
Emerson, Robert D. +1 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Future Agribusiness Challenges: Strategic Uncertainty, Innovation and Structural Change [PDF]
The IFAMR is published by the International Food and Agribusiness Management Association.(IFAMA) www.ifama.orgStrategic uncertainty, innovation, structural change, Agribusiness, Research and Development/Tech Change/Emerging Technologies, Risk and ...
Boehlje, Michael +2 more
core +1 more source