Results 231 to 240 of about 1,327,189 (298)

Pathogenic residue insertion in neuronal nicotinic receptor alters intra- and inter-subunit interactions that tune channel gating. [PDF]

J Biol Chem
Msekela DJ, Sine SM.
europepmc   +1 more source

Multi‐Stimuli Responsive Angstrom‐Scale Two‐Dimensional Channels of Natural Layered Materials

Advanced Materials, EarlyView.
Å‐scale ion channels naturally formed within the interlayers of vermiculite clay enable ionic current modulation in response to mechanical, chemical, and electrical stimuli. Coupled pressure and electric fields induce reversible streaming current (Istream) polarity inversion, which is explained by a modified surface charge regulation model.
Raj Kumar Gogoi, Arghyadeep Paul, Ankit Bhardwaj, Hiran Jyothilal, Narayana R. Aluru, Boya Radha   +5 more
wiley   +1 more source

A structural analysis of the splice-specific functional impact of the pathogenic familial hemiplegic migraine type 1 S218L mutation on Ca_v2.1 P/Q-type channel gating. [PDF]

Mol Brain
Sack AS, Samera GJ, Hissen A, Wester RJ, Garcia E, Adams PJ, Snutch TP.   +6 more
europepmc   +1 more source

Volatile Memristive Devices With Tunable Temporal Dynamics For Event‐Based Sensing

Advanced Materials, EarlyView.
Tunable volatile memristive devices can serve various neural‐inspired tasks that require different time windows of information retention. The ionic‐based volatility of the presented Pt/a‐STO/TaOx/Ta device stack can be reproducibly and controllably tuned in multiple ways.
Dimitrios Spithouris, Johannes Hellwig, Hugh Greatorex, Clemens Wittberg, Panagiotis Koutsogiannis, César Magén, Elisabetta Chicca, Regina Dittmann   +7 more
wiley   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Cooperative Goniopolar and Anomalous Nernst Transverse Thermoelectricity in Kagome Magnets

Advanced Materials, EarlyView.
A cooperative transverse thermoelectric mechanism is realized in kagome magnets, where axis‐dependent goniopolar effects and Berry curvature‐driven anomalous Nernst coexist within the same energy window. In MgMn6Sn6, this intrinsic synergy yields a record room‐temperature transverse thermopower of 15.6 µV K−1, establishing a general strategy for high ...
Honghui Wang, Xiaolong Feng, Haihua Hu, Xuemin Shi, Ralf Koban, Walter Schnelle, Wenzhi Peng, Dazhi Hou, Jianjun Ying, Bin He, Yu Pan, Xiaoyuan Zhou, Claudia Felser   +12 more
wiley   +1 more source

De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor. [PDF]

Cell Mol Life Sci
Xu Y, Song R, Perszyk RE, Chen W, Kim S, Park KL, Allen JP, Nocilla KA, Zhang J, XiangWei W, Tankovic A, McDaniels ED, Sheikh R, Mizu RK, Karamchandani MM, Hu C, Kusumoto H, Pecha J, Cappuccio G, Gaitanis J, Sullivan J, Shashi V, Petrovski S, Jauss RT, Lee HK, Bozarth X, Lynch DR, Helbig I, Pierson TM, Boerkoel CF, Myers SJ, Lemke JR, Benke TA, Yuan H, Traynelis SF.   +34 more
europepmc   +1 more source

Iterative Selection of DNA Nanostructures for Cellular Uptake

Advanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson   +4 more
wiley   +1 more source

Topological Spin‐Texture Transitions in van der Waals Magnets Revealed by X‐Ray Fourier Transform Holography

Advanced Materials, EarlyView.
Applied here for the first time to a 2D material, high‐resolution synchrotron x‐ray Fourier transform holography directly images topological spin textures in Fe3GeTe2. Combined with atomistic tight‐binding simulations including itinerant electrons and Rashba spin‐orbit coupling, the approach reveals labyrinth, skyrmion, and mixed phases, and uncovers ...
Sourav Chowdhury, Soumyaranjan Dash, Michael Schneider, Christopher Klose, Chithra H. Sharma, Lisa‐Marie Kern, Tim A. Butcher, Josefin Fuchs, Santanu Pakhira, Samik DuttaGupta, Takashi Taniguchi, Kenji Watanabe, Sujit Das, Sanjeev Kumar, Bastian Pfau, Amir‐Abbas Haghighirad, Moritz Hoesch   +16 more
wiley   +1 more source

Descriptors to Dynamics: A Materials and Device Perspective on in‐Materio Physical Reservoir Computing for Neuromorphic Edge Intelligence

Advanced Materials, EarlyView.
Intrinsic material dynamics are harnessed as computational resources for neuromorphic in‐materio physical reservoir computing. Defects, ionic motion, interfaces, percolation, geometry, and biasing shape transient states that provide fading memory, nonlinearity, and high‐dimensional projection for simple readout. A descriptor‐to‐dynamics framework links
Kshitij RB Singh, Alif Syafiq Kamarol Zaman, Muzhen Xu, Yuki Usami, Saptarshi Das, Hirofumi Tanaka   +5 more
wiley   +1 more source