Results 91 to 100 of about 285,190 (188)
Polysaccharide-based self-assembling nanohydrogels: An overview on 25-years research on pullulan [PDF]
, 2015 The aim of this overview is to review the evolution of the studies carried out, during more than 25 years, on nanohydrogels obtained by self-assembling of pullulan (PUL) using several hydrophobization strategies.
ALHAIQUE, Franco +4 more
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Protein Quality Control in the Nucleus
Biomolecules, 2014 In their natural environment, cells are regularly exposed to various stress conditions that may lead to protein misfolding, but also in the absence of stress, misfolded proteins occur as the result of mutations or failures during protein synthesis. Since
Sofie V. Nielsen +3 more
doaj +1 more source
Proteostasis collapse is a driver of cell aging and death. [PDF]
, 2019 What molecular processes drive cell aging and death? Here, we model how proteostasis-i.e., the folding, chaperoning, and maintenance of protein function-collapses with age from slowed translation and cumulative oxidative damage.
de Graff, Adam MR +2 more
core
Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity [PDF]
, 2019 The molecular chaperone Heat shock protein 90 (Hsp90) is essential for the folding, stability, and activity of several drivers of oncogenesis. Hsp90 inhibitors are currently under clinical evaluation for cancer treatment, however their efficacy is ...
Backe, Sarah J +11 more
core +1 more source
Exact steady-state velocity of ratchets driven by random sequential adsorption
, 2008 We solve the problem of discrete translocation of a polymer through a pore, driven by the irreversible, random sequential adsorption of particles on one side of the pore.
Ambjörnsson T +11 more
core +1 more source
, 2023 Eine polymorphe Orbitalskulptur, die aus einer 3D-Kohlenstoff -Betonstruktur besteht, die von einem Polypeptidnetzwerk inspiriert ist, das ein geringeres Gewicht und eine geringere Zähigkeit bewirkt und auf einer überfluteten Stadtstraße steht, die von der anthropozentrischen Wärmeakkzeleration herrührt.
openaire +1 more source
, 2014 Citation: 'chaperon' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C00973 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Editorial: The Role of Heat Shock Proteins in Neuroprotection
Frontiers in Pharmacology, 2020 Miklos Santha +3 more
doaj +1 more source
Changes in zebrafish (Danio rerio) lens crystallin content during development. [PDF]
, 2013 PurposeThe roles that crystallin proteins play during lens development are not well understood. Similarities in the adult crystallin composition of mammalian and zebrafish lenses have made the latter a valuable model for examining lens function.
Corbin, Rebecca W +4 more
core +1 more source