Results 181 to 190 of about 226,086 (342)

The dihydropyridine LA1011 modulates multiple Hsp90-co-chaperone interactions relevant to Alzheimer's disease. [PDF]

Cell Stress Chaperones
Jeanne X, Oberoi J, Roe MS, Baud M, Spencer J, Torok Z, Vigh L, Prodromou C.   +7 more
europepmc   +1 more source

3P053 Interaction of the N-terminal domain of Escherichia coli heat shock protein ClpB and protein aggregates during chaperone activity

, 2004
N. Tanaka, Y. Tani, Hirotomo Hattori, Tomoko Tada, Shigeru Kunugi   +4 more
openalex   +2 more sources

Targeting Hsp90 with cemdomespib reduces seizure burden and alters disease course in preclinical epilepsy models

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a chronic neurological disorder characterized by recurrent seizures and frequent cognitive and psychiatric comorbidities. Although current antiseizure medications provide symptomatic relief, they fail to prevent or modify epileptogenesis.
Yara Sheeni, Prince Kumar Singh, Sereen Sandouka, Taige Zhang, Alina Nemirovski, Aseel Saadi, Rhoda Olowe Taiwo, Matthew C. Walker, Tawfeeq Shekh‐Ahmad   +8 more
wiley   +1 more source

39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein. [PDF]

, 1995
Guojun Bu, Hans J. Geuze, Ger J. Strous, Alan L. Schwartz   +3 more
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Editorial: Targeting Cardiac Proteotoxicity

Frontiers in Physiology, 2021
Mark J. Ranek, Mark J. Ranek, Md. Shenuarin Bhuiyan, Md. Shenuarin Bhuiyan, Xuejun Wang   +4 more
doaj   +1 more source

Chaperone-assisted expression and purification of the AML-associated Src-family kinase Fgr in Escherichia coli. [PDF]

J Biol Chem
Gonzalez-Areizaga G, Smithgall TE.
europepmc   +1 more source

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

, 2003
Ann–Hwee Lee, Neal N. Iwakoshi, Laurie H. Glimcher   +2 more
openalex   +1 more source

Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security

Food Bioengineering, EarlyView.
ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob, Gebremedhin Gebreslassie, Etsay Mesele, Tesfakiros Semere   +3 more
wiley   +1 more source

Regulatory role of serine 59 in the oligomeric dynamics and chaperone function of αB-crystallin. [PDF]

Sci Rep
Tender T, Santhoshkumar P, Suleiman L, Hoq MR, Sharma KK.   +4 more
europepmc   +1 more source