High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang +6 more
wiley +1 more source
Hsp70 and Hsp90 post-translational modifications and translating the chaperone code. [PDF]
Backe SJ, Heritz JA, Mollapour M.
europepmc +1 more source
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre +5 more
wiley +1 more source
ER-resident proteins are key players in cartilage and bone homeostasis. [PDF]
Stücker S +3 more
europepmc +1 more source
The role of iron in normal and impaired testicular function
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
<i>In situ</i> analysis of type III secretion chaperone proteins indicates a cytosolic handover of virulence effectors. [PDF]
Pintor K +7 more
europepmc +1 more source
Corrigendum to "Melatonin ameliorates heat stress-induced oxidative apoptosis in mouse spermatocytes via autophagy and ferroptosis pathways" [Cell Stress Chaperones. 2025;30:100078]. [PDF]
Lei YP, Wang J, Yin PL, Jia H, Ma WZ.
europepmc +1 more source
Beyond Folding: Expanding the Functional Landscape of Hsp90 Chaperone Machinery in Health and Disease. [PDF]
Singh MK +8 more
europepmc +1 more source
Molecular chaperones at the host-virus interface: heat shock protein roles in HIV-1 and emerging insights for HIV-2 and dual infection. [PDF]
Arthur SE +8 more
europepmc +1 more source
Origin of class B J-domain proteins involved in amyloid transactions. [PDF]
Domanski P +13 more
europepmc +1 more source

