Hsp70 in mitochondrial biogenesis [PDF]
, 1994 The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
A. Tzagoloff +53 more
core +1 more source
Ubiquitination‐Driven Reprogramming of Proteostasis in Metastasis
Advanced Science, Volume 13, Issue 12, 27 February 2026.The DCAF12–TRiC/CCT axis is a key regulator of metastasis in cancer. By reprogramming proteostasis to ensure efficient protein folding, it drives progression through a dual mechanism: enhancing cancer cell motility and invasiveness while concurrently activating pro‐growth and survival pathways.
Dongping Wei, Jiayan Chen, Yaping Xu
wiley +1 more source
Versatile platform for nanotechnology based on circular permutations of chaperonin protein [PDF]
, 2010 The present invention provides chaperonin polypeptides which are modified to include N-terminal and C-terminal ends that are relocated from the central pore region to various different positions in the polypeptide which are located on the exterior of the
Chan, Suzanne L. +5 more
core +1 more source
Molecular characterization of the Corynebacterium pseudotuberculosis hsp60-hsp10 operon, and evaluation of the immune response and protective efficacy induced by hsp60 DNA vaccination in mice [PDF]
, 2011 Background Heat shock proteins (HSPs) are important candidates for the development of vaccines because they are usually able to promote both humoral and cellular immune responses in mammals.
Marcilia P Costa +13 more
core +1 more source
The Prospect of Heat Shock Protein (Hsp) as Biomarker of Oral Disease [PDF]
, 2012 The prevalence of oral diseases is increasing and caused by many factors. It can be caused by environmental, genetic, Malignancy or side effects of dental treatment.
Amin, M. N. (Muhammad)
core
100 years of Einstein's theory of Brownian motion: from pollen grains to protein trains [PDF]
, 2005 Experimental verification of the theoretical predictions made by Albert Einstein in his paper, published in 1905, on the molecular mechanisms of Brownian motion established the existence of atoms.
A Einstein +7 more
core +3 more sources
Growth of Rhodococcus sp. strain BCP1 on gaseous n-alkanes: New metabolic insights and transcriptional analysis of two soluble di-iron monooxygenase genes [PDF]
, 2015 Rhodococcus sp. strain BCP1 was initially isolated for its ability to grow on gaseous n-alkanes, which act as inducers for the co-metabolic degradation of low-chlorinated compounds.
Cappelletti M. +6 more
core +2 more sources
Analysis of the proteome and the secretome of animal trypanosomes : a standardized analytical method to look for new molecular targets [PDF]
, 2007 The causative agents of animal trypanosomosis are various species of protozoan parasites belonging to the genus Trypanosoma, among which T. congolense and T. evansi are the major pathogenic species. The extra cellular position of the trypanosomes implies
Bengaly, Zakaria +10 more
core
Directed transport as a mechanism for protein folding in vivo
, 2009 We propose a model for protein folding in vivo based on a Brownian-ratchet mechanism in the multidimensional energy landscape space. The device is able to produce directed transport taking advantage of the assumed intrinsic asymmetric properties of the ...
Alberts B. +9 more
core +1 more source