Results 1 to 10 of about 51,381 (340)
A Speciation Study on the Perturbing Effects of Iron Chelators on the Homeostasis of Essential Metal Ions. [PDF]
PLoS ONE, 2015 A number of reports have appeared in literature calling attention to the depletion of essential metal ions during chelation therapy on β-thalassaemia patients.
Guido Crisponi +6 more
doaj +11 more sources
Predictors of Non-adherence to iron chelation therapy in pediatric thalassemia patients
Journal of Rawalpindi Medical College, 2022 Objective: This study was conducted to identify predictors of non-adherence to iron chelation therapy among children suffering from β-thalassemia major across different treatment regimens.
Muniba Kanwal +3 more
doaj +3 more sources
Barriers to adherence to iron chelation therapy among adolescent with transfusion dependent thalassemia [PDF]
Frontiers in Pediatrics, 2022 Study backgroundThalassemia is the commonest genetic blood disorder in Malaysia which requires life-long blood transfusions. From a total of 7,984 thalassemia patients in Malaysia, adolescent age group account for the highest number of patients (2,680 ...
Rafaa Mohamed +3 more
doaj +2 more sources
A MULTICENTER ICET-A STUDY ON AGE AT MENARCHE AND MENSTRUAL CYCLES IN PATIENTS WITH TRANSFUSION-DEPENDENT THALASSEMIA (TDT) WHO STARTED EARLY CHELATION THERAPY WITH DIFFERENT CHELATING AGENTS. [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2023 . Objective: To evaluate the age at menarche and menstrual characteristics in patients with transfusion-dependent thalassemia (TDT) who started early chelation therapy (≤ 3 years) with a variety of chelating agents.
SALVATORE DI MAIO +13 more
doaj +2 more sources
The Role of Iron Chelation Therapy in Colorectal Cancer: A Systematic Review on Its Mechanisms and Therapeutic Potential [PDF]
Cancer MedicineBackground Despite significant therapeutic advancements in recent decades, colorectal cancer (CRC) continues to exhibit high rates of mortality and morbidity.
Gihani Vidanapathirana +4 more
doaj +2 more sources
Endocrine Complications and the Effect of Compliance with Chelation Therapy in Patients with Beta Thalassemia Major in Eastern Province of Saudi Arabia [PDF]
Journal of Blood Medicine, 2022 Fatema Habbash,* Wegdan Al-Bati,* Howra Al-Hashim,* Maryam Aldossari,* Ahmed Alali, Khalid Alalyani, Zainab Al-Ebrahim, Nouf Hamed, Samma Eraqe, Ziyad Binayfan, Azzam Al Marri, Thamer Aljaber Department of Family and Community Medicine ...
Habbash F +11 more
doaj +2 more sources
Annals of the New York Academy of Sciences, 2023 Abstract Combination chelation therapies are considered in transfusion‐dependent thalassemia patients for whom monotherapy regimens have failed to achieve iron balance or intensification of iron chelation therapy is required for the rapid reduction of excess iron to avoid permanent organ damage.
openaire +5 more sources
Haematologica, 2023 CALYPSO (clinicaltrials gov. Identifier: NCT02435212), a randomized, open-label, multicenter, phase II study evaluated the compliance, clinical benefits, and safety of deferasirox granules and dispersible tablets (DT) in pediatric patients with iron ...
Ali T. Taher +8 more
doaj +1 more source
Journal of Internal Medicine, 1997 Desferrioxamine (DFX) remains the most effective and safe iron chelator for treatment of patients with transfusional iron overload. It is usually given by intermittent subcutaneous infusions for 8–12 h on 4–6 days weekly using a battery‐driven pump. Disposable balloon infusers provide a suitable method of giving continuous subcutaneous infusions with ...
A V, Hoffbrand, B, Wonke
openaire +2 more sources
Taiwanese Journal of Obstetrics & Gynecology, 2020 Objective: To report cases of use of chelation therapy during pregnancy which resulted in favorable outcomes for the babies. Materials and methods: In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian ...
Maria Grazia Piccioni +8 more
doaj +1 more source