Results 141 to 150 of about 2,402,251 (269)

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

EDTA chelation therapy, without added vitamin C, decreases oxidative DNA damage and lipid peroxidation.

, 2009
International audienceChelation therapy is thought to not only remove contaminating metals but also to decrease free radical production. However, in standard ethylene diamine tetracetic acid (EDTA) chelation therapy, high doses of vitamin C with ...
Osman, Mireille, Waters, Robert, S., Anderson, Richard, A., Fernholz, Karen, Hininger-Favier, Isabelle, Roussel, Anne Marie   +5 more
core   +1 more source

Endocrine complications in patients with β-thalassemia major receiving iron-chelation therapy. [PDF]

Ther Adv Endocrinol Metab
Al-Sanabra OM, Abbas MA, Hazàa AA, Hazà WJ.   +3 more
europepmc   +1 more source

Characterisation of individual ferritin response in patients receiving chelation therapy. [PDF]

Br J Clin Pharmacol, 2022
Borella E, Oosterholt S, Magni P, Della Pasqua O.   +3 more
europepmc   +1 more source

Assessment of Adherence to Iron Chelation Therapy Among Thalassemia Patients in Palestine. [PDF]

Anemia
Zabadi HA, Ieran Z, Taha I.
europepmc   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Chelation Therapy for Rare Earth Element Toxicity: Current Evidence, Challenges and Future Directions. [PDF]

Basic Clin Pharmacol Toxicol
Domingo JL.
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Beliefs of Jordanian Children with Thalassemia toward Using Iron Chelation Therapy

, 2016
Adherence to thalassemia treatment including chelation drugs is influenced by numerous factors. This study aims to explore beliefs about iron chelation therapy and adherence to this medication in Jordanian children with thalassemia major.
Ghada Mohammad, Abu Shosha
core  

Medication Adherence, Clinical Outcomes, and Health-Related Quality of Life Among Pediatric Patients with β-Thalassemia Major Receiving Iron Chelation Therapy: A Multicenter Study from Punjab, Pakistan. [PDF]

Patient Prefer Adherence
Muneeb A, Inam S, Ali I, Alshehri AA, Siddiq M, Ali S.   +5 more
europepmc   +1 more source