Results 151 to 160 of about 4,480,665 (367)

Gamma‐Glutamyl Cysteine Ligase Activity as a Proxy for Human T Cell Function and Drug‐Induced Immunosuppression

Advanced Science, EarlyView.
GLed, a reversible lanthanide‐based GSH sensor that enables real‐time, single‐cell measurement of Gamma–Glutamyl Cysteine Ligase (GCL) activity ‐whose role in human T cells remains unclear‐ is developed. GLed directly links GCL activity to T cell effector functions and reveals its modulation by immunosuppressive drugs, identifying GCL as a critical ...
Francisco Fueyo‐González, Carmen Salto‐Giron, Mehek Ningoo, Laura Espinar‐Barranco, Rafael Salto, Jose Manuel Paredes, Rosario Herranz, Angel Orte, Miguel Fribourg, Juan A. González‐Vera   +9 more
wiley   +1 more source

An Observational Study of Glomerular Functions in Beta-thalassemia Major Children by Schwartz Formula and Technetium 99m Diethylenetriaminepentaacetic Acid Renogram

Archives of Medicine and Health Sciences
Background and Aim: Kidney dysfunction is reported in significant number of beta thalassemia major children. The aim of this study was to determine the prevalence of glomerular dysfunction in beta-thalassemia major children on regular blood transfusion ...
Sukanta Mandal, Tathagata Bose, Rachna Gulati, Manish Singh Ahuja   +3 more
doaj   +1 more source

Prospective changes of pancreatic iron in patients with thalassemia major and association with chelation therapy. [PDF]

Blood Adv, 2023
Meloni A, Pistoia L, Ricchi P, Allò M, Rosso R, Cuccia L, Casini T, Cecinati V, Serra M, Rossi V, Righi R, Renne S, Vallone A, Positano V, Cademartiri F.   +14 more
europepmc   +1 more source

The Effect of Chelation Therapy with Succimer on Neuropsychological Development in Children Exposed to Lead [PDF]

, 2001
Walter J. Rogan, Kim N. Dietrich, James H. Ware, Douglas W. Dockery, M.P. Salganik, Jerilynn Radcliffe, Robert L. Jones, N. Beth Ragan, J. Julian Chisolm, George G. Rhoads   +9 more
openalex   +1 more source

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

Advanced Science, EarlyView.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li, Ying Qu, Bingyang Chu, Tingkui Wu, Meng Pan, Dong Mo, Lang Li, Yang Ming, Yun Yang, Meng Wang, Xinlong He, Zhiyong Qian   +11 more
wiley   +1 more source

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia. [PDF]

Cochrane Database Syst Rev, 2023
Geneen LJ, Dorée C, Estcourt LJ.
europepmc   +1 more source

Designing Environmental Policy: Lessons from the Regulation of Mercury Emissions [PDF]

In its waning days, the Clinton administration decided that it was appropriate to regulate mercury emissions from power plants. The incoming Bush administration had to decide how best to regulate these emissions.
Gayer, Ted, Hahn, Robert W.
core   +1 more source

Cu(II) and Fe(III) complexes of sulphadoxine mixed with pyramethamine: Synthesis, characterization, antimicrobial and toxicology study [PDF]

, 2012
Two new mixed ligands metal complexes of sulphadoxine and pyramethamine were prepared by using CuCl2.6H2O and FeCl3.6H2O. The complexes were characterized by elemental analysis, melting point determination, molar conductivity, metal content analysis (AAS)
Adekoya, J. A., Ajanaku, K. O., Ajani, O. O., Ehi-Eromosele, C. O., Obaleye, J. A., Ogunniran, K. O.   +5 more
core  

Iron chelation, angiogenesis and tumor therapy [PDF]

, 2003
Tobias Linden, Roland H. Wenger
openalex   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

Advanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang, Wengui Lu, Zhifei Cheng, Luyao Wang, Zhenzhen Jiang, Yike Yue, Pengyu Jiang, Zehua Xia, Lei He, Fengying Wang, Limin Wu, Qi Wang, Hui Han   +12 more
wiley   +1 more source