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Importance of iron chelation therapy [PDF]
Thalassemia Reports, 2011 It is necessary to remember that today patients have different options of chelation treatment, as desferrioxamine, deferiprone and deferasirox are available. However, a patient has to be compliant with treatments.
A. Varoğlu
doaj +4 more sources
A systematic review of adherence to iron chelation therapy among children and adolescents with thalassemia. [PDF]
Ann Med, 2022 Introduction Iron chelation therapy (ICT) is essential to prevent complications of iron overload in patients with transfusion-dependent thalassaemia.
Reddy PS, Locke M, Badawy SM.
europepmc +2 more sources
A Speciation Study on the Perturbing Effects of Iron Chelators on the Homeostasis of Essential Metal Ions. [PDF]
PLoS ONE, 2015 A number of reports have appeared in literature calling attention to the depletion of essential metal ions during chelation therapy on β-thalassaemia patients.
Guido Crisponi +6 more
doaj +11 more sources
European Journal of Haematology, 2023 Iron overload is a pathological condition resulting from a congenital impairment of its regulation, increased intestinal iron absorption secondary to bone marrow erythroid hyperplasia, or a chronic transfusional regimen.
A. Bruzzese +11 more
semanticscholar +3 more sources
Annals of the New York Academy of Sciences, 2023 Combination chelation therapies are considered in transfusion‐dependent thalassemia patients for whom monotherapy regimens have failed to achieve iron balance or intensification of iron chelation therapy is required for the rapid reduction of excess iron
Y. Aydinok
semanticscholar +3 more sources
Is Chelation Therapy a Potential Treatment for Parkinson's Disease? [PDF]
Int J Mol Sci, 2021 Iron loading in some brain regions occurs in Parkinson’s Disease (PD), and it has been considered that its removal by iron chelators could be an appropriate therapeutic approach.
Ward RJ +3 more
europepmc +2 more sources
Chelation therapy and autism [PDF]
BMJ, 2006 EDITOR—More children are being diagnosed as having autism, and there are currently no treatments based on aetiology.1 Consequently, a number of controversial, unproved, alternative treatments have arisen. The recent death of an autistic child after a medication error with intravenous chelation therapy has brought one purported aetiology based treatment
Yashwant Sinha +2 more
openalex +4 more sources
EDTA chelation therapy for cardiovascular disease: a systematic review [PDF]
BMC Cardiovascular Disorders, 2005 Background Numerous practitioners of both conventional and complementary and alternative medicine throughout North America and Europe claim that chelation therapy with EDTA is an effective means to both control and treat cardiovascular disease.
Wu Ping, Seely Dugald MR, Mills Edward J
doaj +2 more sources
Adherence to Iron Chelation Therapy and Its Determinants. [PDF]
Int J Hematol Oncol Stem Cell Res, 2021 Background: Thalassemia is a chronic disease requiring lifelong treatment. The adherence to regular iron chelation therapy is important to ensure complication-free survival and good quality of life. The study aim to assess the adherence to iron chelation
Sidhu S +4 more
europepmc +2 more sources
Barriers to adherence to iron chelation therapy among adolescent with transfusion dependent thalassemia [PDF]
Frontiers in Pediatrics, 2022 Study backgroundThalassemia is the commonest genetic blood disorder in Malaysia which requires life-long blood transfusions. From a total of 7,984 thalassemia patients in Malaysia, adolescent age group account for the highest number of patients (2,680 ...
Rafaa Mohamed +3 more
doaj +2 more sources