Results 41 to 50 of about 4,480,665 (367)

Bistable equilibrium points of mercury body burden [PDF]

, 2007
In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion
Boulos, Areen, Owhadi, Houman
core   +2 more sources

Healthcare resource utilization and direct costs of transfusion-dependent thalassemia patients in Dubai, United Arab Emirates: a retrospective cost-of-illness study

BMC Health Services Research, 2022
Background Patients with transfusion-dependent thalassemia (TDT) require lifelong blood transfusions and iron chelation therapy. Thus, patients afflicted with TDT often have to undergo blood transfusion and iron chelation therapy, which causes a major ...
Shaikha Alshamsi, Samer Hamidi, Hacer Ozgen Narci   +2 more
doaj   +1 more source

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone [PDF]

, 2020
Alterations in the NRF2/KEAP1 pathway result in the constitutive activation of NRF2, leading to the aberrant induction of antioxidant and detoxification enzymes, including NQO1.
Boothman, David A., DeNicola, Gina M., Elkins, Cody M., Falzone, Aimee, Haura, Eric B., Prieto-Farigua, Nicolas, Torrente, Laura   +6 more
core   +1 more source

Knowledge, Attitude, and Practice of Young Paediatricians About Chelation Therapyin Transfusion-Dependent Thalassemia Major Children

Pakistan Armed Forces Medical Journal, 2022
Objective: To determine the knowledge, attitude, and practice of young paediatricians about chelation therapy in transfusiondependent thalassemia major children.
Misbah Fakih, Faisal Basheer, Saad Ateeq, Farooq Ikram, Hafsa Asad, Qamar uz Zaman Khan   +5 more
doaj   +1 more source

New Perspectives in Iron Chelation Therapy for the Treatment of Neurodegenerative Diseases

Pharmaceuticals, 2018
Iron chelation has been introduced as a new therapeutic concept for the treatment of neurodegenerative diseases with features of iron overload. At difference with iron chelators used in systemic diseases, effective chelators for the treatment of ...
M. Núñez, P. Chaná-Cuevas
semanticscholar   +1 more source

Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine

Cancer Science, 2020
Cancer cells have high iron requirements due to their rapid growth and proliferation. Iron depletion using iron chelators has a potential in cancer treatment.
Kana Komoto, Takahiro Nomoto, S. E. Muttaqien, Hiroyasu Takemoto, M. Matsui, Y. Miura, N. Nishiyama   +6 more
semanticscholar   +1 more source

Antioxidant and antihemolytic activities of methanol extract of Hyssopus angustifolius [PDF]

, 2012
This study was designed to evaluate antioxidant and antihemolytic activities of Hyssopus angustifolius flower, stem and leaf methanol extracts by employing various in vitro assays.
Alinezhad, H., Azimi, R., Baharfar, R., Hellio, Claire, Nabavi, S., Nabavi, S., Zare, M.   +6 more
core   +3 more sources

Beliefs about chelation among thalassemia patients

Health and Quality of Life Outcomes, 2012
Background Understanding patients’ views about medication is crucial to maximize adherence. Thalassemia is a congenital blood disorder requiring chronic blood transfusions and daily iron chelation therapy.
Trachtenberg Felicia L, Mednick Lauren, Kwiatkowski Janet L, Neufeld Ellis J, Haines Dru, Pakbaz Zahra, Thompson Alexis A, Quinn Charles T, Grady Robert, Sobota Amy, Olivieri Nancy, Horne Robert, Yamashita Robert   +12 more
doaj   +1 more source

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

Haematologica, 2019
Iron overload due to red blood cell (RBC) transfusions is associated with morbidity and mortality in lower-risk myelodysplastic syndrome (MDS) patients. Many studies have suggested improved survival after iron chelation therapy (ICT), but valid data are ...
Marlijn P A Hoeks, Ge Yu, S. Langemeijer, S. Crouch, L. de Swart, P. Fenaux, A. Symeonidis, J. Čermák, E. Hellström-Lindberg, G. Sanz, R. Stauder, M. Holm, M. Mittelman, K. Mądry, L. Malcovati, A. Tatic, A. Almeida, U. Germing, A. Savic, N. G. Šimec, D. Culligan, R. Itzykson, A. Guerci-Bresler, B. Slama, J. Droste, C. V. van Marrewijk, A. A. van de Loosdrecht, N. Blijlevens, M. van Kraaij, D. Bowen, T. D. de Witte, Alex Smith   +31 more
semanticscholar   +1 more source

Biological activities and chemical composition of methanolic extracts of selected Autochthonous microalgae strains from the Red Sea [PDF]

, 2015
Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules.
Carolina Bruno De Sousa, Florêncio Nogueira, Fouzi Mouffouk, Hugo Pereira, José Manuel, João Varela, Khalid M. Abu-salah, Luísa Barreira, Luísa Custódio, Maria João Rodrigues, Marta Oliveira, Nuno Da Rosa Neng, Radhouan Ben-hamadou, Salman A. Alrokayan, The Red Sea   +14 more
core   +4 more sources