Results 81 to 90 of about 28,637 (186)

Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma

Nature Communications
Anti-disialoganglioside (GD2) antibody therapy has provided clinical benefit to patients with neuroblastoma however efficacy is likely impaired by the immunosuppressive tumor microenvironment. We have previously defined a link between intratumoral copper
Jourdin R. C. Rouaen, Antonietta Salerno, Tyler Shai-Hee, Jayne E. Murray, Giulia Castrogiovanni, Charlotte McHenry, Toni Rose Jue, Vu Pham, Jessica Lilian Bell, Ensieh Poursani, Emanuele Valli, Riccardo Cazzoli, Naomi Damstra, Delia J. Nelson, Kofi L. P. Stevens, Jonathan Chee, Iveta Slapetova, Maria Kasherman, Renee Whan, Francis Lin, Blake J. Cochran, Nicodemus Tedla, Feyza Colakoglu Veli, Aysen Yuksel, Chelsea Mayoh, Federica Saletta, Daniele Mercatelli, Tatyana Chtanova, Arutha Kulasinghe, Daniel Catchpoole, Giuseppe Cirillo, Maté Biro, Holger N. Lode, Fabio Luciani, Michelle Haber, Juliet C. Gray, Toby N. Trahair, Orazio Vittorio   +37 more
doaj   +1 more source

An AN OBSERVATIONAL STUDY OF LIVER FUNCTIONS IN MULTIPLE TRANSFUSED THALASSEMIA PATIENTS ON REGULAR CHELATION THERAPY VERSUS IRREGULAR CHELATION THERAPY IN A TERTIARY CARE CENTER OF JAIPUR, RAJASTHAN [PDF]

Objectives: The aim of our study was to determine liver functions in thalassemia patients on regular versus irregular chelation therapy. Methods: This was an observational study conducted in the department of pediatrics in a tertiary care hospital ...
YADAV, SHWETA, SHARMA, ABHISHEK KUMAR, YADAV, RAJVEER SINGH, GOYAL, TRAPTA, PAL, NIKITA, RAY, SANDIP   +5 more
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EDTA chelation therapy, without added vitamin C, decreases oxidative DNA damage and lipid peroxidation. [PDF]

, 2009
International audienceChelation therapy is thought to not only remove contaminating metals but also to decrease free radical production. However, in standard ethylene diamine tetracetic acid (EDTA) chelation therapy, high doses of vitamin C with ...
Osman, Mireille, Waters, Robert, S., Anderson, Richard, A., Fernholz, Karen, Hininger-Favier, Isabelle, Roussel, Anne Marie   +5 more
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Unveiling Extramedullary Hematopoiesis: A Case Report Highlighting the Causes, Symptoms, and Management Strategies

Thalassemia Reports
Extramedullary hematopoiesis (EMH) serves as a compensatory mechanism in chronic hemolytic anemias, such as thalassemia, and can result in spinal cord compression.
Konstantinos Manganas, Aikaterini Xydaki, Angeliki Kotsiafti, Olympia Papakonstantinou, Sophia Delicou   +4 more
doaj   +1 more source

Case Series: EDTA chelation for band keratopathy

Kerala Journal of Ophthalmology
The purpose of this study was to report a case series of visually significant calcific band keratopathy (CBK) associated with chronic uveitis and systemic hypercalcemia, which markedly decreased in severity after dipotassium ethylenediaminetetraacetic ...
Pallavi Dhawan, Ruchika Agarwal, Archana Yadav, Shivangi Singh, Harnoor Jot   +4 more
doaj   +1 more source

Durable Red Blood Cell Transfusion Independence in a Patient with an MDS/MPN Overlap Syndrome Following Discontinuation of Iron Chelation Therapy

Case Reports in Hematology, 2015
Background. Hematologic improvement (HI) occurs in some patients with acquired anemias and transfusional iron overload receiving iron chelation therapy (ICT) but there is little information on transfusion status after stopping chelation. Case Report.
Harpreet Kochhar, Chantal S. Leger, Heather A. Leitch   +2 more
doaj   +1 more source

Compliance and Barriers of Beta-Thalassaemia Patients towards Iron Chelation Therapy in Hospital Keningau, Sabah [PDF]

, 2019
Long-term survival in beta-thalassaemia major is strongly influenced by adherence to iron chelation therapy.
Jawatankuasa Kerja PSM UMS
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New Perspectives on the Impact of Iron Chelation Therapy on the Gut Microbiome in Thalassemia Patients

Thalassemia Reports
Thalassemia, a genetic condition characterized by defective hemoglobin synthesis, is often managed with transfusion therapy, which can lead to iron overload—a significant contributor to morbidity and mortality due to organ damage and pathogenic ...
Sara Deumić, Neira Crnčević, Mirsada Hukić, Muamer Dizdar, Monia Avdić   +4 more
doaj   +1 more source

Evaluation of intakes of transuranics influenced by chelation therapy [PDF]

, 1994
Once an intake of transuranics occurs, there are only three therapeutic procedures available to the physician for reducing the intake and mitigating the dose: excision of material from wounds, removal of material from the lungs with lavage, and chelation
LaBone, T. R.
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An Observational Study of Glomerular Functions in Beta-thalassemia Major Children by Schwartz Formula and Technetium 99m Diethylenetriaminepentaacetic Acid Renogram

Archives of Medicine and Health Sciences
Background and Aim: Kidney dysfunction is reported in significant number of beta thalassemia major children. The aim of this study was to determine the prevalence of glomerular dysfunction in beta-thalassemia major children on regular blood transfusion ...
Sukanta Mandal, Tathagata Bose, Rachna Gulati, Manish Singh Ahuja   +3 more
doaj   +1 more source