Results 211 to 220 of about 9,197 (244)
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Sanguinarine and Chelerythrine as Inhibitors of Aromatic Amino Acid Decarboxylase
Journal of Enzyme Inhibition, 1996Quaternary benzo[c]phenanthridine alkaloids sanguinarine, chelerythrine and their dihydroderivatives were tested as inhibitors of aromatic amino acid decarboxylase (EC 4.1, 1.28, AAD) from rat liver. Sanguinarine and chelerythrine exhibited strong inhibition of AAD with Ki 1.2 x 10(-4) M and 5.8 x 10(-4) M, respectively, while no inhibitory effect was ...
J, Drsata, J, Ulrichová, D, Walterová
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Staurosporine but not chelerythrine inhibits regeneration in hippocampal organotypic cultures
Synapse, 1997A mechanical lesion in hippocampal organotypic cultures is followed by a recovery process involving scar formation, sprouting of fibres and formation of new functional synapses. Here we tested the effect of staurosporine and chelerythrine, two protein kinase C (PKC) inhibitors, on this lesion-induced neurite outgrowth of Shaffer collaterals.
Toni, Nicolas +2 more
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, 2019
Chelerythrine (CHE) is an alkaloid with significant anticancer activity. However, CHE is required repeat administration to achieve the treatment effect due to its short half-life. To address this issue, a novel CHE controlled release drug delivery system
Yan-Hong Wang +5 more
semanticscholar +1 more source
Chelerythrine (CHE) is an alkaloid with significant anticancer activity. However, CHE is required repeat administration to achieve the treatment effect due to its short half-life. To address this issue, a novel CHE controlled release drug delivery system
Yan-Hong Wang +5 more
semanticscholar +1 more source
Chelerythrine chloride binding of guanosine in aqueous solution
Chinese Chemical Letters, 2009Abstract In this work, the interaction between chelerythrine (CHE) and guanosine is studied using UV–vis and fluorescence measurements at various temperatures. The UV–vis spectra show that the increasing guanosine concentrations result in the decreasing absorption intensity and red shift of CHE E absorption band (267 nm). The fluorescence spectra are
Fan Liu +5 more
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Life Science, 2019
The present study aimed to evaluate the renoprotective effects of chelerythrine (CHE), a protein kinase C inhibitor, on neonatal rats after partial unilateral ureteral obstruction (UUO) surgery.
Bo Shi +5 more
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The present study aimed to evaluate the renoprotective effects of chelerythrine (CHE), a protein kinase C inhibitor, on neonatal rats after partial unilateral ureteral obstruction (UUO) surgery.
Bo Shi +5 more
semanticscholar +1 more source
Hydrochromism behaviors of solid forms of chelerythrine hydrochloride
CrystEngComm, 2019Salt formation has the potential to produce smart stimulus–response fluorescent materials without modifying the main chemical structures, especially for unstable stem-nucleus structures, and this is investigated in this work.
Meiqi Li +3 more
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Journal of Veterinary Pharmacology and Therapeutics, 2018
Sanguinarine (SA) and chelerythrine (CHE) are the main active components of the phytogenic livestock feed additive, Sangrovit®. However, little information is available on the pharmacokinetics of Sangrovit® in poultry.
Nan-Xi Hu +9 more
semanticscholar +1 more source
Sanguinarine (SA) and chelerythrine (CHE) are the main active components of the phytogenic livestock feed additive, Sangrovit®. However, little information is available on the pharmacokinetics of Sangrovit® in poultry.
Nan-Xi Hu +9 more
semanticscholar +1 more source
Neurochemistry International, 2011
Glycine transporter inhibitors modulate the transmission of pain signals. Since it is well known that extracts from medicinal plants such as Chelidonium majus exhibit analgesic properties, we investigated the effects of alkaloids typically present in this plant on glycine transporters.
Frantisek, Jursky, Martina, Baliova
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Glycine transporter inhibitors modulate the transmission of pain signals. Since it is well known that extracts from medicinal plants such as Chelidonium majus exhibit analgesic properties, we investigated the effects of alkaloids typically present in this plant on glycine transporters.
Frantisek, Jursky, Martina, Baliova
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Journal of Separation Science, 2018
A novel type of magnetic molecularly imprinted polymer was prepared for the selective enrichment and isolation of chelerythrine from Macleaya cordata (Willd) R. Br.
M. Zhong +4 more
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A novel type of magnetic molecularly imprinted polymer was prepared for the selective enrichment and isolation of chelerythrine from Macleaya cordata (Willd) R. Br.
M. Zhong +4 more
semanticscholar +1 more source
[Advance in studies on pharmacological activities of chelerythrine].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014Chelerythrine is a kind of benzo[c] phenanthridine alkaloids, with such pharmacological activities as antitumor, antibiosis and anti-inflammation, which is widely found in plant of Fumariaceae, Papaveraceae, Ranunculaceae and Rutaceae families.
Pei-Qing, Wang +2 more
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