Results 21 to 30 of about 624 (180)
Preparation of chelidonine highly loaded poly(lactide-co-glycolide)-based nanoparticles using a single emulsion method: Cytotoxic effect on MDA-MB-231 cell line [PDF]
Journal of HerbMed Pharmacology, 2022 Introduction: Chelidonine, a bio-active component of Chelidonium majus, has been investigated for its anti-proliferative effects on various cancer cell lines with multidrug resistance (MDR).
Zahra Hamidia +3 more
doaj +1 more source
Chelidonine Induces Concurrent Elevation of pSer-STAT3 and Bcl-2 Levels in a Mitotic Subpopulation of Human T-Leukemia/Lymphoma Cells. [PDF]
Int J Mol SciSignal transducer and activator of transcription 3 (STAT3) is a transcription factor that regulates a broad spectrum of genes with oncogenic potential, thereby serving as a critical driver of tumorigenesis.
Baddour S +5 more
europepmc +2 more sources
Opposing Effects of Chelidonine on Tyrosine and Serine Phosphorylation of STAT3 in Human Uveal Melanoma Cells [PDF]
International Journal of Molecular Sciences, 2021 Tamás Kovacs +2 more
exaly +2 more sources
The Herbal Pair <i>Polygonum hydropiper</i> <i>L-Coptis chinensis Franch</i> Attenuate DSS-Induced Ulcerative Colitis by Modulating Metabolism and Intestinal Flora. [PDF]
Food Sci NutrPH‐CC regulates dysbiosis in intestinal flora and metabolic disorders in UC mice by reducing the abundance of specific bacterial groups, thereby alleviating inflammatory damage to the colonic mucosa and improving the overall condition of UC. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which dysbiosis of the intestinal ...
Zhu F +6 more
europepmc +2 more sources
Inhibitory Activity of Conferone on FAK Activity and Glutamine Metabolism in Human Colorectal Cancer. [PDF]
J Cell Mol MedABSTRACT Colorectal cancer (CRC) is a major global cause of death, with metastases and chemotherapy resistance contributing to poor outcomes. To identify natural compounds with anticancer potential against CRC and elucidate their action mechanisms, the cytotoxicity of 37 natural compounds was evaluated against the HCT116, leading to the identification ...
Ong HTM +5 more
europepmc +2 more sources
Molecules, 2022 The Chelidonium majus plant is rich in biologically active isoquinoline alkaloids. These alkaline polar compounds are isolated from raw materials with the use of acidified water or methanol; next, after alkalisation of the extract, they are extracted ...
Maciej Strzemski +9 more
doaj +1 more source
ELECTROPHORESIS, Volume 44, Issue 13-14, Page 1114-1142, July 2023., 2023 Abstract The process of choosing the most proper technique for studying the molecular interactions is based on critical factors such as instrumentation complexity, automation, experimental procedures, analysis time, consumables, and cost‐value. This review has tracked the use of affinity capillary electrophoresis (ACE) and microscale thermophoresis ...
Mufarreh Asmari +5 more
wiley +1 more source
EFSA Journal, Volume 21, Issue 6, June 2023., 2023 Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Macleaya cordata (Willd.) R. Br. extract and leaves (Sangrovit® Extra) when used as a zootechnical feed additive (functional group: other zootechnical additives) for all poultry species (excluding laying and breeding ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
wiley +1 more source