Results 41 to 50 of about 1,235 (206)

Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014-2023). [PDF]

open access: yesChem Biodivers
This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Sipoloni VM   +5 more
europepmc   +2 more sources

THE PHARMACOLOGICAL EFFICACY OF THE EXTEMPORANEOUS GEL DIAVENOL [PDF]

open access: yesAnnals of Mechnikov's Institute, 2017
Introduction. Diavenol - new extemporaneous gel for the treatment of venous ulcers. The gel contains a synergistic combination C. majus quinolizidine alkaloids and riboflavin. Activate tissue regeneration shown previously for riboflavin, and сheleretrin /
Martynov AV   +13 more
doaj   +1 more source

Modulatory Effect of Chelidonium majus Extract and Its Alkaloids on LPS-Stimulated Cytokine Secretion in Human Neutrophils

open access: yesMolecules, 2020
Due to certain differences in terms of molecular structure, isoquinoline alkaloids from Chelidonium majus engage in various biological activities.
Sylwia Zielińska   +7 more
doaj   +1 more source

Isolation of Alkaloids from Papaver rhoeas (Papaveraceae) Wildly Grown in Iraq

open access: yesIraqi Journal of Pharmaceutical Sciences, 2021
The plant Papaver rhoeas ,which belongs to family Papaveraceae and known as common poppy is wildly grown in Iraq .It was used in traditional medicine in wide range of diseases including inflammation, diarrhea, sleep disorders, treatment of cough ...
Amenah Ayad Lafta, Maha N. Hamad
doaj   +1 more source

Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids [PDF]

open access: yes, 2003
Copyright © 2003 Elsevier Ireland Ltd. All rights reserved.The alkaloids from Chelidonium majus L. which had a significant inhibitory effect in mitochondrial respiration were those which contain a positive charge due to a quaternary nitrogen atom, i.e ...
Arrabaça, João Daniel   +3 more
core   +1 more source

Targeting NRAS-Mutant Cancers with the Selective STK19 Kinase Inhibitor Chelidonine

open access: yesClinical Cancer Research, 2020
Purpose: Oncogenic mutations in NRAS promote tumorigenesis. Although novel anti-NRAS inhibitors are urgently needed for the treatment of cancer, the protein is generally considered “undruggable” and no effective therapies have yet reached the clinic ...
L. Qian   +5 more
semanticscholar   +1 more source

Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway

open access: yesBMC Cancer, 2006
Background The anticancer drug Ukrain (NSC-631570) which has been specified by the manufacturer as semisynthetic derivative of the Chelidonium majus L.
Plasswilm Ludwig   +10 more
doaj   +1 more source

The β-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype [PDF]

open access: yes, 2013
The end replication problem, which occurs in normal somatic cells inducing replicative senescence, is solved in most cancer cells by activating telomerase.
Albino   +59 more
core   +1 more source

In vitro Cytotoxic Activity of Four Plants Used in Persian Traditional Medicine [PDF]

open access: yes, 2013
Purpose: The aim of this study was to investigate in vitro cytotoxic activity of four methanolic crude plant extracts against panel cell lines. Methods: Methanolic extracts were tested for their possible antitumor activity and cytotoxicity using the 3-(4,
Behzad Baradaran   +3 more
core   +1 more source

The Interference of Selected Cytotoxic Alkaloids with the Cytoskeleton: An Insight into Their Modes of Action

open access: yesMolecules, 2016
Alkaloids, the largest group among the nitrogen-containing secondary metabolites of plants, usually interact with several molecular targets. In this study, we provide evidence that six cytotoxic alkaloids (sanguinarine, chelerythrine, chelidonine ...
Xiaojuan Wang   +4 more
doaj   +1 more source

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