Results 61 to 70 of about 1,235 (206)

Acetylcholinesterase and Butyrylcholinesterase Inhibitory Compounds from (Papaveraceae)

open access: yesNatural Product Communications, 2010
The roots and aerial parts of Chelidonium majus L. were extracted with EtOH and fractionated using CHCl 3 and EtOH. Repeated column chromatography, preparative TLC and crystallization led to the isolation of five isoquinoline alkaloids, stylopine ( 3 ...
Lucie Cahlíková   +5 more
doaj   +1 more source

Hepatotoxicity induced by greater celandine (Chelidonium majus L.): a review of the literature [PDF]

open access: yes, 2017
The available literature assessing Chelidonium majus L. (CM) hepatotoxicity potential, and its risk to benefit assessment has been reviewed in this paper.
Busardò, F. P   +6 more
core  

Systematic Evaluation of Chromatographic Parameters for Isoquinoline Alkaloids on XB‐C18 Core‐Shell Column Using Different Mobile Phase Compositions

open access: yesJournal of Analytical Methods in Chemistry, Volume 2018, Issue 1, 2018., 2018
Chelidonium majus L. is a rich source of isoquinoline alkaloids with confirmed anti‐inflammatory, choleretic, spasmolytic, antitumor, and antimicrobial activities. However, their chromatographic analysis is difficult because they may exist both in charged and uncharged forms and may result in the irregular peak shape and the decrease in chromatographic
Ireneusz Sowa   +9 more
wiley   +1 more source

Ensaios densitométricos para a avaliação, ao longo de um ciclo anual, d e alcalóides solúveis em água de raízes de Chelidonium majus L. (Papaveracea), nos Açores [PDF]

open access: yes, 1995
Prepararam-se extractos de alcalóides solúveis em água de raízes de Chelidonium majus L. (celidónia), colhida em terrenos incultos nos Açores, mensalmente, ao longo de um ano.
Pavão, Maria Leonor   +1 more
core  

Imaging microtubule dynamics: A new frontier in biomarker development for neurodegenerative diseases

open access: yesAlzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract Microtubules (MTs) are essential components of the neuronal cytoskeleton, playing key roles in intracellular transport, synaptic function, and overall neuronal integrity. Although MT dynamics and MT‐binding agents have been studied extensively, their potential as biomarkers in neurodegenerative diseases has received limited attention. Emerging
Naresh Damuka   +2 more
wiley   +1 more source

The Elevation of LC‐ESI‐Q‐TOF‐MS Response in the Analysis of Isoquinoline Alkaloids from Some Papaveraceae and Berberidaceae Representatives

open access: yesJournal of Analytical Methods in Chemistry, Volume 2017, Issue 1, 2017., 2017
Twenty‐five methanol extracts obtained from various representatives of Papaveraceae and Berberidaceae botanical families (genera: Papaver, Argemone, Eschscholzia, Chelidonium, Glaucium, and Berberis) were screened for their alkaloid content in an optimized method suitable for the LC‐ESI‐Q‐TOF‐MS analysis. Twelve pharmacologically important isoquinoline
Wirginia Kukula-Koch   +1 more
wiley   +1 more source

Intracellular Accumulation as an Indicator of Cytotoxicity to Screen Hepatotoxic Components of Chelidonium majus L. by LC–MS/MS

open access: yesMolecules, 2019
A novel strategy was developed to identify hepatotoxic compounds in traditional Chinese medicines (TCMs). It is based on the exposure of HL-7702 cells to a TCM extract, followed by the identification and further determination of potential hepatotoxic ...
Cuiting Wu   +4 more
doaj   +1 more source

HPTLC Fingerprints of Various Secondary Metabolites in the Traditional Medicinal Herb Hypochaeris radicata L.

open access: yesJournal of Botany, Volume 2016, Issue 1, 2016., 2016
The aim of this work was to elucidate the various secondary metabolites such as alkaloids, flavonoids, glycosides, saponins, and terpenoids in the methanolic leaf and root extracts of Hypochaeris radicata, a most important traditional medicinal plant species in Nilgiris, the Western Ghats, India, using high performance thin layer chromatography (HPTLC).
Jamuna Senguttuvan   +2 more
wiley   +1 more source

Effect of chelidonine on growth, invasion, angiogenesis and gene expression in head and neck cancer cell lines

open access: yesOncology Letters, 2018
The greater celandine ‘Chelidonium majus’ and its main alkaloid chelidonine have previously been shown to exert high cytotoxicity against cancer cells. Furthermore, chelidonine is proposed to possess pro-apoptotic and anti-metastatic properties.
R. Herrmann   +3 more
semanticscholar   +1 more source

Alkaloids in the pharmaceutical industry: Structure, isolation and application [PDF]

open access: yesHemijska Industrija, 2003
By the end of the 18th and the beginning of the 19th century a new era began in medicine, pharmaceutics and chemistry that was strongly connected with alkaloids and alkaloid drugs.
Nikolić Milan, Đorđević Siniša M.
doaj   +1 more source

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